Journal Articles

Open Access

Cancer drug delivery in the nano era: An overview and perspectives (Review)

Zhen Li, Shirui Tan, Shuan Li, Qiang Shen, Kunhua Wang

Pages: 611-624 Published online on: 14 June 2017
Open Access

Anti-angiogenesis target therapy for advanced osteosarcoma (Review)

Lu Xie, Tao Ji, Wei Guo

Pages: 625-636 Published online on: 21 June 2017

Anticancer potential of bioactive peptides from animal sources (Review)

Linghong Wang, Chao Dong, Xian Li, Wenyan Han, Xiulan Su

Pages: 637-651 Published online on: 03 July 2017

The function of miRNAs in hepatocarcinogenesis induced by hepatitis B virus X protein (Review)

Ziyao Wang, Zhongjun Wu, Ping Huang

Pages: 652-664 Published online on: 13 June 2017
Open Access

Exosomes: New players in cancer (Review)

Wei Guo, Yibo Gao, Ning Li, Fei Shao, Chunni Wang, Pan Wang, Zhenlin Yang, Renda Li, Jie He

Pages: 665-675 Published online on: 13 June 2017

Progress in mass spectrometry-based proteomic research of tumor hypoxia (Review)

Zhiqi Gao, Gang Luo, Bing Ni

Pages: 676-684 Published online on: 23 June 2017
Open Access

Concomitant Mycobacterium tuberculosis infection promotes lung tumor growth through enhancing Treg development

Yan Zhou, Zhangguo Hu, Shuhui Cao, Bo Yan, Jialin Qian, Hua Zhong

Pages: 685-692 Published online on: 19 June 2017
Open Access

Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells

Nakako Izumi Nakajima, Atsuko Niimi, Mayu Isono, Takahiro Oike, Hiro Sato, Takashi Nakano, Atsushi Shibata

Pages: 693-702 Published online on: 30 June 2017
Open Access

Galangin suppresses human laryngeal carcinoma via modulation of caspase-3 and AKT signaling pathways

Hai-Xu Wang, Chen Tang

Pages: 703-714 Published online on: 29 June 2017
Open Access

Apigenin overcomes drug resistance by blocking the signal transducer and activator of transcription 3 signaling in breast cancer cells

Hye‑Sook Seo, Jin Mo Ku, Hyeong Sim Choi, Jong‑Kyu Woo, Byung Hoon Lee, Doh Sun Kim, Hyun Jong Song, Bo‑Hyoung Jang, Yong Cheol Shin, Seong‑Gyu Ko

Pages: 715-724 Published online on: 26 June 2017
Open Access

miR-543 functions as a tumor suppressor in glioma in vitro and in vivo

Liang Xu, Ju Yu, Zhongyong Wang, Qing Zhu, Wenjie Wang, Qing Lan

Pages: 725-734 Published online on: 12 June 2017
Open Access

Centromere protein U is a potential target for gene therapy of human bladder cancer

Sheng Wang, Beibei Liu, Jiajun Zhang, Wei Sun, Changyuan Dai, Wenyan Sun, Qingwen Li

Pages: 735-744 Published online on: 30 June 2017
Open Access

P18 peptide, a functional fragment of pigment epithelial-derived factor, inhibits angiogenesis in hepatocellular carcinoma via modulating VEGF/VEGFR2 signalling pathway

Xin Wang, Peng Xiu, Fuhai Wang, Jingtao Zhong, Honglong Wei, Zongzhen Xu, Feng Liu, Jie Li

Pages: 755-766 Published online on: 14 June 2017
Open Access

The homologous recombination protein RAD51 is a promising therapeutic target for cervical carcinoma

Qian Chen, Dongge Cai, Mu Li, Xiaoling Wu

Pages: 767-774 Published online on: 15 June 2017
Open Access

Distinctive crypt shape in a sessile serrated adenoma/polyp: Distribution of Ki67-, p16INK4a-, WNT5A-positive cells and intraepithelial lymphocytes

Kenji Hisamatsu, Kei Noguchi, Hiroyuki Tomita, Aoi Muto, Natsumi Yamada, Kazuhiro Kobayashi, Akihiro Hirata, Tomohiro Kanayama, Ayumi Niwa, Kazuhisa Ishida, Takayuki Nakashima, Yuichiro Hatano, Natsuko Suzui, Tatsuhiko Miyazaki, Akira Hara

Pages: 775-784 Published online on: 15 June 2017
Open Access

Glioma cells enhance angiogenesis and inhibit endothelial cell apoptosis through the release of exosomes that contain long non-coding RNA CCAT2

Hai-Li Lang, Guo-Wen Hu, Bo Zhang, Wei Kuang, Yong Chen, Lei Wu, Guo-Hai Xu

Pages: 785-798 Published online on: 22 June 2017
Open Access

Microarray analysis reveals differentially expressed lncRNAs in benign epithelial ovarian cysts and normal ovaries

Xiaoguang Liu, Chencheng Dai, Genmei Jia, Sujuan Xu, Ziyi Fu, Juan Xu, Qing Li, Hongjie Ruan, Pengfei Xu

Pages: 799-808 Published online on: 22 June 2017
Open Access

Anticancer and apoptosis‑inducing effects of quercetin in vitro and in vivo

Mahmoud Hashemzaei, Amin Delarami Far, Arezoo Yari, Reza Entezari Heravi, Kaveh Tabrizian, Seyed Mohammad Taghdisi, Sarvenaz Ekhtiari Sadegh, Konstantinos Tsarouhas, Dimitrios Kouretas, George Tzanakakis, Dragana Nikitovic, Nikita Yurevich Anisimov, Demetrios   A. Spandidos, Aristides M. Tsatsakis, Ramin Rezaee

Pages: 819-828 Published online on: 28 June 2017
Open Access

Nicotinic acid impairs assembly of leading edge in glioma cells

Xiangcai Yang, Shuting Mei, Hua Niu, Jiejing Li

Pages: 829-836 Published online on: 27 June 2017
Open Access

Tetramethylpyrazine inhibits prostate cancer progression by downregulation of forkhead box M1

Yi Zhou, Zhigang Ji, Weigang Yan, Zhien Zhou, Hanzhong Li, Yu Xiao

Pages: 837-842 Published online on: 29 June 2017
Open Access

MicroRNA-345 inhibits hepatocellular carcinoma metastasis by inhibiting YAP1

Hui Zhang, Hui Liu, Huaqiang Bi

Pages: 843-849 Published online on: 30 June 2017
Open Access

Utilization of E-cadherin by monocytes from tumour cells plays key roles in the progression of bone invasion by oral squamous cell carcinoma

Jingjing Quan, Qian Du, Yuluan Hou, Zhiyuan Wang, Jingyuan Zhang

Pages: 850-858 Published online on: 23 June 2017
Open Access

BMH-21 inhibits viability and induces apoptosis by p53-dependent nucleolar stress responses in SKOV3 ovarian cancer cells

Xinxu Fu, Lu Xu, Ling Qi, Hongyan Tian, Dan Yi, Yang Yu, Shibing Liu, Songyan Li, Ye Xu, Chunyan Wang

Pages: 859-865 Published online on: 23 June 2017
Open Access

Overexpression of A disintegrin and metalloprotease 10 promotes tumor proliferation, migration and poor prognosis in hypopharyngeal squamous cell carcinoma

Chuanjin Ding, Qicheng Zhang, Yan Chen, Xiaobo Zhang, Pei Wu, Zhenxin Zhang

Pages: 866-874 Published online on: 27 June 2017
Open Access

Bioinformatic analysis reveals potential properties of human Claudin-6 regulation and functions

Dongjing Lin, Yaxiong Guo, Yanru Li, Yang Ruan, Mingzi Zhang, Xiangshu Jin, Minlan Yang, Yan Lu, Peiye Song, Shuai Zhao, Bing Dong, Yinping Xie, Qihua Dang, Chengshi Quan

Pages: 875-885 Published online on: 27 June 2017
Open Access

Intratumoral and peritumoral expression of CD68 and CD206 in hepatocellular carcinoma and their prognostic value

Chun-Xia Ren, Rui-Xue Leng, Yin-Guang Fan, Hai-Feng Pan, Bao-Zhu Li, Chang-Hao Wu, Qiang Wu, Na-Na Wang, Qi-Ru Xiong, Xiao-Ping Geng, Dong-Qing Ye

Pages: 886-898 Published online on: 21 June 2017
Open Access

Targeting the PD-L1/DNMT1 axis in acquired resistance to sorafenib in human hepatocellular carcinoma

Jianhua Liu, Yahui Liu, Lingyu Meng, Kai Liu, Bai Ji

Pages: 899-907 Published online on: 14 June 2017

Expression of cell cycle-related proteins in oropharyngeal squamous cell carcinoma based on human papilloma virus status

Koudai Tsuchida, Tamotsu Sugai, Noriyuki Uesugi, Kazuyuki Ishida, Kazuto Matsuura, Ikuro Sato, Kiyoto Shiga, Hiroaki Sato

Pages: 908-916 Published online on: 14 June 2017

Stromal antigen 2 functions as a tumor suppressor in bladder cancer cells

Han Wang, Jianhua Zhong, Chenglong Wu, Yang Liu, Jinghua Zhang, Xiaowen Zou, Yan Chen, Jinfeng Su, Gang Yang, Yuantang Zhong, Aifa Tang

Pages: 917-925 Published online on: 12 June 2017

Cetuximab promotes SN38 sensitivity via suppression of heat shock protein 27 in colorectal cancer cells with wild-type RAS

Takashi Ishida, Yoshiyuki Ishii, Masashi Tsuruta, Koji Okabayashi, Shingo Akimoto, Kaoru Koishikawa, Hirotoshi Hasegawa, Yuko Kitagawa

Pages: 926-932 Published online on: 21 June 2017

Inhibition of Skp2 suppresses the proliferation and invasion of osteosarcoma cells

Lu Ding, Rong Li, Xiaoping Han, Yubo Zhou, Hua Zhang, Yong Cui, Wu Wang, Jingping Bai

Pages: 933-940 Published online on: 12 June 2017

lncRNA XIST interacts with miR-140 to modulate lung cancer growth by targeting iASPP

Yongjun Tang, Ruoxi He, Jian An, Pengbo Deng, Li Huang, Wei Yang

Pages: 941-948 Published online on: 26 June 2017

Inactivation of AKT, ERK and NF-κB by genistein derivative, 7-difluoromethoxyl-5,4'-di-n-octylygenistein, reduces ovarian carcinoma oncogenicity

Yingxia Ning, Meng Xu, Xiaocheng Cao, Xiangding Chen, Xin Luo

Pages: 949-958 Published online on: 09 June 2017

Low expression of microRNA-320b correlates with tumorigenesis and unfavorable prognosis in glioma

Qiao-Li Lv, Hong Du, Yan-Ling Liu, Yuang-Tao Huang, Gui-Hua Wang, Xue Zhang, Shu-Hui Chen, Hong-Hao Zhou

Pages: 959-966 Published online on: 28 June 2017

Klotho suppresses tumor progression via inhibiting IGF-1R signaling in T‑cell lymphoma

Xiangxiang Zhou, Ya Zhang, Ying Li, Yangyang Xu, Lingyan Zhang, Ying Li, Xin Wang

Pages: 967-974 Published online on: 22 June 2017

KLF4 inhibits colorectal cancer cell proliferation dependent on NDRG2 signaling

Yongzheng Ma, Lin Wu, Xuewu Liu, Yuqiao Xu, Wei Shi, Ye Liang, Libo Yao, Jianyong Zheng, Jian Zhang

Pages: 975-984 Published online on: 21 June 2017

Involvement of mitochondrial dynamics in the antineoplastic activity of cisplatin in murine leukemia L1210 cells

Xiao-Jian Han, Sheng-Lan Shi, Yong-Fang Wei, Li-Ping Jiang, Miao-Yu Guo, Hong-Li Wu, Yu-Ying Wan

Pages: 985-992 Published online on: 28 June 2017

Hypoxia- and acidosis-driven aberrations of secreted microRNAs in endometrial cancer in vitro

Julia Eismann, Marc Hirschfeld, Thalia Erbes, Gerta Rücker, Markus Jäger, Andrea Ritter, Daniela Weiss, Gerald Gitsch, Sebastian Mayer

Pages: 993-1004 Published online on: 13 June 2017

CIP2A, an oncoprotein, is associated with cell proliferation, invasion and migration in laryngeal carcinoma cells

Xu-Dong Chen, Shi-Xiong Tang, Jian-Hua Zhang, Li-Tao Zhang, Yao-Wen Wang

Pages: 1005-1012 Published online on: 27 June 2017

Microvesicles released from human embryonic stem cell derived-mesenchymal stem cells inhibit proliferation of leukemia cells

Yuan Ji, Yongbin Ma, Xiang Chen, Xianyan Ji, Jianyi Gao, Lei Zhang, Kai Ye, Fuhao Qiao, Yao Dai, Hui Wang, Xiangmei Wen, Jiang Lin, Jiabo Hu

Pages: 1013-1020 Published online on: 16 June 2017

Vasohibin-1 inhibits angiogenesis and suppresses tumor growth in renal cell carcinoma

Guangning Zhao, Ren Na, Liming Li, Huiyuan Xiao, Na Ding, Yan Sun, Ruifa Han

Pages: 1021-1028 Published online on: 22 June 2017

Desipramine induces apoptosis in hepatocellular carcinoma cells

Dong Kwon Yang, Shang-Jin Kim

Pages: 1029-1034 Published online on: 15 June 2017

Silencing DEK downregulates cervical cancer tumorigenesis and metastasis via the DEK/p-Ser9-GSK-3β/p-Tyr216-GSK-3β/β-catenin axis

Xiaoyang Xu, Lin Zou, Qiuhui Yao, Yanbo Zhang, Li Gan, Liangdan Tang

Pages: 1035-1042 Published online on: 14 June 2017

B7-H3 promotes the proliferation, migration and invasiveness of cervical cancer cells and is an indicator of poor prognosis

Yi Li, Jingjing Zhang, Sai Han, Qiuhong Qian, Qian Chen, Lu Liu, Youzhong Zhang

Pages: 1043-1050 Published online on: 19 June 2017

Suppression of gastric cancer by extract from the tuber of amorphophallus konjac via induction of apoptosis and autophagy

Xi Chen, Lin-Qing Yuan, Lin-Jie Li, Yao Lv, Pei-Feng Chen, Lei Pan

Pages: 1051-1058 Published online on: 22 June 2017

SIRT6 inhibits growth of gastric cancer by inhibiting JAK2/STAT3 pathway

Jianmei Zhou, Ang Wu, Xiaoting Yu, Jianwei Zhu, Hui Dai

Pages: 1059-1066 Published online on: 27 June 2017

MicroRNA-138 inhibits cell proliferation in hepatocellular carcinoma by targeting Sirt1

Jia Luo, Pan Chen, Wei Xie, Feiyue Wu

Pages: 1067-1074 Published online on: 03 July 2017

MicroRNA-448 suppresses metastasis of pancreatic ductal adenocarcinoma through targeting JAK1/STAT3 pathway

Dan-Li Yu, Tao Zhang, Kun Wu, Yan Li, Juan Wang, Jun Chen, Xiao-Quan Li, Xing-Guo Peng, Jia-Ning Wang, Li-Guo Tan

Pages: 1075-1082 Published online on: 03 July 2017

Downregulation of PRRX1 via the p53-dependent signaling pathway predicts poor prognosis in hepatocellular carcinoma

Mingming Fan, Jun Shen, Hu Liu, Zhijian Wen, Jue Yang, Pinghua Yang, Kai Liu, Yanxin Chang, Jicheng Duan, Kai Lu

Pages: 1083-1090 Published online on: 03 July 2017

Gonadotropins promote human ovarian cancer cell migration and invasion via a cyclooxygenase 2-dependent pathway

Dingqing Feng, Tingting Zhao, Keqin Yan, Haiyan Liang, Jing Liang, Ying Zhou, Weidong Zhao, Bin Ling

Pages: 1091-1098 Published online on: 03 July 2017

Robust cancer-specific gene expression by a novel cassette with hTERT and CMV promoter elements

Masakiyo Sakaguchi, Takuya Sadahira, Hideo Ueki, Rie Kinoshita, Hitoshi Murata, Ken-Ichi Yamamoto, Junichiro Futami, Yasutomo Nasu, Kazuhiko Ochiai, Hiromi Kumon, Nam-Ho Huh, Masami Watanabe

Pages: 1108-1114 Published online on: 12 June 2017

PRMT1 expression is elevated in head and neck cancer and inhibition of protein arginine methylation by adenosine dialdehyde or PRMT1 knockdown downregulates proliferation and migration of oral cancer cells

Chun-Yi Chuang, Chien-Ping Chang, Yu-Jen Lee, Wei-Long Lin, Wen-Wei Chang, Jia-Sian Wu, Ya-Wen Cheng, Huei Lee, Chuan Li

Pages: 1115-1123 Published online on: 21 June 2017

Effect of OATP1B1 genetic polymorphism on the uptake of tamoxifen and its metabolite, endoxifen

Chun-Mei Gao, Zhichen Pu, Chunyuan He, Dahu Liang, Yuanwei Jia, Xiaolong Yuan, Guangji Wang, Haitang Xie

Pages: 1124-1132 Published online on: 16 June 2017

MicroRNA-31 inhibits tumor invasion and metastasis by targeting RhoA in human gastric cancer

Fulin Ge, Changzheng Wang, Weihua Wang, Wenhui Liu, Benyan Wu

Pages: 1133-1139 Published online on: 27 June 2017

Long non-coding RNA C5orf66-AS1 is downregulated in pituitary null cell adenomas and is associated with their invasiveness

Guoqiang Yu, Chuzhong Li, Weiyan Xie, Zhuang Wang, Hua Gao, Lihua Cao, Lingtong Hao, Yazhuo Zhang

Pages: 1140-1148 Published online on: 22 June 2017

Lentivirus‑mediated knockdown of chondroitin polymerizing factor inhibits glioma cell growth in vitro

Yang-Hua Fan, Bing Xiao, Shi-Gang Lv, Min-Hua Ye, Xin-Gen Zhu, Miao-Jing Wu

Pages: 1149-1155 Published online on: 19 June 2017

miR-30a inhibits glioma progression and stem cell‑like properties by repression of Wnt5a

Yonghong Zhang, Zhi Wu, Lichao Li, Min Xie

Pages: 1156-1162 Published online on: 16 June 2017

The inhibitory effects of deep-sea water on doxorubicin‑induced epithelial-mesenchymal transition

So-Young Chun, Soyoung Kim, Kyung-Soo Nam

Pages: 1163-1171 Published online on: 16 June 2017

Anti-proliferation and anti-metastasis effect of barbaloin in non-small cell lung cancer via inactivating p38MAPK/Cdc25B/Hsp27 pathway

Zhang Zhang, Wei Rui, Zi-Chen Wang, Da-Xin Liu, Lin Du

Pages: 1172-1180 Published online on: 27 June 2017

MicroRNA and target mRNA selection through invasion and cytotoxicity cell modeling and bioinformatics approaches in esophageal squamous cell carcinoma

Mu Lu, Yaqin Song, Wenbo Fu, Yang Liu, Shitao Huai, Xiaobin Cui, Lijuan Pang, Lan Yang, Yutao Wei

Pages: 1181-1189 Published online on: 30 June 2017

miR-367 promotes tumor growth by inhibiting FBXW7 in NSCLC

Guodong Xiao, Xiao Gao, Xin Sun, Chengcheng Yang, Boxiang Zhang, Ruiying Sun, Guanghong Huang, Xiang Li, Jian Liu, Ning Du, Dapeng Liu, Rui Liang, Hong Ren, Sida Qin

Pages: 1190-1198 Published online on: 27 June 2017

MAPK and Hippo signaling pathways crosstalk via the RAF-1/MST-2 interaction in malignant melanoma

Ruizheng Feng, Junsheng Gong, Lina Wu, Lei Wang, Baolin Zhang, Gang Liang, Huixia Zheng, Hong Xiao

Pages: 1199-1205 Published online on: 30 June 2017

Torilis japonica extract fraction compound, EGFR-targeted inhibition of cancer abnormal metastasis in A549 lung cancer cells

Guen Tae Kim, Sang-Yong Kim, Young Min Kim

Pages: 1206-1212 Published online on: 30 June 2017

Identification and characterization of miR-96, a potential biomarker of NSCLC, through bioinformatic analysis

Tonghui Cai, Jie Long, Hongyan Wang, Wanxia Liu, Yajie Zhang

Pages: 1213-1223 Published online on: 27 June 2017

Norcantharidin inhibits IL-6-induced epithelial‑mesenchymal transition via the JAK2/STAT3/TWIST signaling pathway in hepatocellular carcinoma cells

Yebo Gao, Weidong Li, Rui Liu, Qiujun Guo, Jie Li, Yanju Bao, Honggang Zheng, Shulong Jiang, Baojin Hua

Pages: 1224-1232 Published online on: 30 June 2017

Sodium cantharidinate induces HepG2 cell apoptosis through LC3 autophagy pathway

Ran Tao, Wen-Yi Sun, De-Hai Yu, Wei Qiu, Wei-Qun Yan, Yan-Hua Ding, Guang-Yi Wang, Hai-Jun Li

Pages: 1233-1239 Published online on: 03 July 2017

MicroRNA-342 inhibits the progression of glioma by directly targeting PAK4

Xianghe Lu, Haowen Wang, Zhipeng Su, Lin Cai, Wenfeng Li

Pages: 1240-1250 Published online on: 03 July 2017

Suppression of SIRT6 by miR-33a facilitates tumor growth of glioma through apoptosis and oxidative stress resistance

Mingze Chang, Lin Qiao, Bin Li, Juanhong Wang, Gejuan Zhang, Wenzhen Shi, Zhiqin Liu, Naibing Gu, Zhengli Di, Xinlai Wang, Ye Tian

Pages: 1251-1258 Published online on: 03 July 2017

CtBP2 is associated with angiogenesis and regulates the apoptosis of prostate cancer cells

Qiang Xuan, Xiaoge Zhong, Weidong Li, Zengnan Mo, Yuanjie Huang, Yanling Hu

Pages: 1259-1267 Published online on: 28 June 2017

Salivary miR-93 and miR-200a as post-radiotherapy biomarkers in head and neck squamous cell carcinoma

Thomas Greither, Freya Vorwerk, Matthias Kappler, Matthias Bache, Helge Taubert, Thomas Kuhnt, Jeremias Hey, Alexander W. Eckert

Pages: 1268-1275 Published online on: 28 June 2017

MicroRNA-605 functions as a tumor suppressor by targeting INPP4B in melanoma

Lan Chen, Yaxuan Cao, Dongyun Rong, Ye Wang, Yu Cao

Pages: 1276-1286 Published online on: 22 June 2017

WNT10A/β‑catenin pathway in tumorigenesis of papillary thyroid carcinoma

Tianyi Dong, Zhun Zhang, Wenhong Zhou, Xiangyu Zhou, Chong Geng, Lap Kam Chang, Xingsong Tian, Shili Liu

Pages: 1287-1294 Published online on: 03 July 2017

miR-138 inhibits gastric cancer growth by suppressing SOX4

Lei Pang, Bai Li, Baisong Zheng, Liang Niu, Liang Ge

Pages: 1295-1302 Published online on: 22 June 2017

PRMT2β, a C-terminal splice variant of PRMT2, inhibits the growth of breast cancer cells

Jing Zhong, Ya-Jun Chen, Ling Chen, Ying-Ying Shen, Qing-Hai Zhang, Jing Yang, Ren-Xian Cao, Xu-Yu Zu, Ge-Bo Wen

Pages: 1303-1311 Published online on: 03 July 2017

Matrine inhibits the metastatic properties of human cervical cancer cells via downregulating the p38 signaling pathway

Xiaoling Wu, Jie Zhou, Dongge Cai, Mu Li

Pages: 1312-1320 Published online on: 03 July 2017
Journal Cover

August 2017
Volume 38 Issue 2

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2016 Impact Factor: 2.662
Ranked #31/217 Oncology
(total number of cites)

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