Early Online

Open Access

KIFC1 promotes the proliferation of hepatocellular carcinoma in vitro and in vivo

Xing Wang, Meng Wang, Xing‑Yue Li, Jian Li, Dian‑Peng Zhao

Published online on: October 14, 2019

Hypoxia induces immunogenic cell death of cancer cells by enhancing the exposure of cell surface calreticulin in an endoplasmic reticulum stress‑dependent manner

Yu Kyeong Han, Ga‑Young Park, Min Ji Bae, Joong Sun Kim, Wol Soon Jo, Chang Geun Lee

Published online on: October 14, 2019

MicroRNAs associated with microvascular invasion in hepatocellular carcinoma and their prognostic impacts in patients undergoing hepatic resection

Sung Kyu Song, Min Geun Park, Seung‑Keun Park, Chul‑Woon Chung, Yongkeun Park

Published online on: October 14, 2019
Open Access

High gene expression levels of VEGFA and CXCL8 in the peritumoral brain zone are associated with the recurrence of glioblastoma: A bioinformatics analysis

Xiaobin Luo, Shangyi Xu, Yali Zhong, Tianqi Tu, Youlin Xu, Xianglong Li, Bin Wang, Fubing Yang

Published online on: October 14, 2019
Open Access

Cytochrome C inhibits tumor growth and predicts favorable prognosis in clear cell renal cell carcinoma

Zhiguo Liu, Xiancheng Zhao, Liang Zhang, Bing Pei

Published online on: October 14, 2019
Open Access

Accelerated elimination of human cancer cells by a CD40 agonist antibody combined with a PD‑1 antagonist in CD4‑depleted mice

Soon‑Hyun Ahn, Joo Yeon Choi, Seong Dong Kim, Sung Joon Park, Hyojin Kim

Published online on: October 14, 2019
Open Access

Mutant‑allele tumor heterogeneity in malignant glioma effectively predicts neoplastic recurrence

Pengfei Wu, Wei Yang, Jianxing Ma, Jingyu Zhang, Maojun Liao, Lunshan Xu, Minhui Xu, Liang Yi

Published online on: October 11, 2019
Open Access

Screening of core genes and pathways in breast cancer development via comprehensive analysis of multi gene expression datasets

Jie Bai, Xiaoyu Zhang, Xiaoning Kang, Lijun Jin, Peng Wang, Zunyi Wang

Published online on: October 11, 2019
Open Access

Shikonin regulates invasion and autophagy of cultured colon cancer cells by inhibiting yes‑associated protein

Jing Zhu, Lei Zhao, Bin Luo, Wang Sheng

Published online on: October 11, 2019
Open Access

Role of apoptosis repressor with caspase recruitment domain (ARC) in cancer (Review)

Zhongjie Yu, Qi Li, Yi An, Xiatian Chen, Ziqian Liu, Zhe Li, Jinning Gao, Lynn Htet Htet Aung, Peifeng Li

Published online on: October 11, 2019
Open Access

Five extracellular matrix‑associated genes upregulated in oral tongue squamous cell carcinoma: An integrated bioinformatics analysis

Pingping Zhong, Liya Liu, Aling Shen, Zhongxin Chen, Xiaoyan Hu, Yichao Cai, Jie Lin, Bangyan Wang, Jiesen Li, Youqin Chen, Jun Peng

Published online on: October 11, 2019

The roles of estrogen and estrogen receptors in gastrointestinal disease (Review)

Changmei Chen, Xiang Gong, Xiaoxu Yang, Xianhui Shang, Qian Du, Qiushi Liao, Rui Xie, Yuanshou Chen, Jingyu Xu

Published online on: October 11, 2019
Open Access

Celecoxib suppresses lipopolysaccharide‑stimulated oral squamous cell carcinoma proliferation in vitro and in vivo

Hisato Yoshida, Hitoshi Yoshimura, Shinpei Matsuda, Satoshi Yamamoto, Masahiro Ohmori, Keiichi Ohta, Takashi Ryoke, Hayato Itoi, Tamotsu Kiyoshima, Motohiro Kobayashi, Kazuo Sano

Published online on: October 10, 2019

Molecular mechanism of Helicobacter pylori‑induced autophagy in gastric cancer (Review)

Fan Zhang, Cong Chen, Jike Hu, Ruiliang Su, Junqiang Zhang, Zhijian Han, Hao Chen, Yumin Li

Published online on: October 10, 2019
Open Access

A nomogram for the prediction of overall survival in patients with stage II and III non‑small cell lung cancer using a population‑based study

Yi Liao, Xue Wang, Ping Zhong, Guofang Yin, Xianming Fan, Chengliang Huang

Published online on: October 10, 2019
Open Access

JMJD3 promotes the epithelial‑mesenchymal transition and migration of glioma cells via the CXCL12/CXCR4 axis

Shuang Zou, Dongchen Zhang, Zhongwei Xu, Xiaochang Wen, Yan Zhang

Published online on: October 9, 2019

In vitro antitumor effects of FGFR and PI3K inhibitors on human papillomavirus positive and negative tonsillar and base of tongue cancer cell lines

Stefan Holzhauser, Ourania N. Kostopoulou, Anna Ohmayer, Birthe K.A. Lange, Torbjörn Ramqvist, Teodora Andonova, Cinzia Bersani, Malin Wickström, Tina Dalianis

Published online on: October 9, 2019

Decreased expression levels of ELOVL6 indicate poor prognosis in hepatocellular carcinoma

Hui Li, Xianling Wang, Jun Tang, Haibo Zhao, Min Duan

Published online on: October 9, 2019
Open Access

Claudin‑1 silencing increases sensitivity of liver cancer HepG2 cells to 5‑fluorouracil by inhibiting autophagy

Hui Tong, Tao Li, Weihua Qiu, Zhecheng Zhu

Published online on: October 8, 2019
Open Access

Functional impact of the long non‑coding RNA MEG3 deletion by CRISPR/Cas9 in the human triple negative metastatic Hs578T cancer cell line

Carlos Deocesano‑Pereira, Raquel Arminda Carvalho Machado, Henrique Cesar de Jesus‑Ferreira, Thiago Marchini, Tulio Felipe Pereira, Ana Claudia Oliveira Carreira, Mari Cleide Sogayar

Published online on: October 8, 2019
Open Access

Cyclin‑dependent kinase 9 expression and its association with CD8+ T cell infiltration in microsatellite‑stable colorectal cancer

Jiefu Wang, Jia Liu, Fei Tian, Yang Zhan, Dalu Kong

Published online on: October 8, 2019
Open Access

PACAP and PAC1 receptor expression in pancreatic ductal carcinoma

Sandor Ferencz, Dora Reglodi, Balint Kaszas, Attila Bardosi, Denes Toth, Zsofia Vekony, Viktoria Vicena, Oszkar Karadi, Dezso Kelemen

Published online on: October 8, 2019
Open Access

GABRQ expression is a potential prognostic marker for patients with clear cell renal cell carcinoma

Dongjun Lee, Mihyang Ha, Chae Mi Hong, Jayoung Kim, Su Min Park, Dongsu Park, Dong Hyun Sohn, Ho Jin Shin, Hak‑Sun Yu, Chi Dae Kim, Chi‑Dug Kang, Myoung‑Eun Han, Sae‑Ock Oh, Yun Hak Kim

Published online on: October 4, 2019
Open Access

Prognostic genes of melanoma identified by weighted gene co‑expression network analysis and drug repositioning using a network‑based method

Lu Wang, Chuan‑Yuan Wei, Yuan‑Yuan Xu, Xin‑Yi Deng, Qiang Wang, Jiang‑Hui Ying, Si‑Min Zhang, Xin Yuan, Tian‑Fan Xuan, Yu‑Yan Pan, Jian‑Ying Gu

Published online on: October 4, 2019
Open Access

Prognostic value and prospective molecular mechanism of miR‑100‑5p in hepatocellular carcinoma: A comprehensive study based on 1,258 samples

Qing‑Lin He, Shan‑Yu Qin, Lin Tao, Hong‑Jian Ning, Hai‑Xing Jiang

Published online on: October 4, 2019
Open Access

Impact of antiretroviral drugs on PD‑L1 expression and copy number gains with clinical outcomes in HIV‑positive and ‑negative locally advanced cervical cancers

Kongsak Loharamtaweethong, Songkhun Vinyuvat, Jidapa Thammasiri, Sakchai Chitpakdee, Chalermpak Supakatitham, Napaporn Puripat

Published online on: October 4, 2019
Open Access

Predictive significance of T cell subset changes during ex vivo generation of adoptive cellular therapy products for the treatment of advanced non‑small cell lung cancer

Lefu Huang, Guoliang Qiao, Michael A. Morse, Xiaoli Wang, Xinna Zhou, Jiangping Wu, Amy Hobeika, Jun Ren, Herbert K. Lyerly

Published online on: October 4, 2019
Open Access

[Retracted] Breast metastasis from a pulmonary adenocarcinoma: Case report and review of the literature

Alessandro Sanguinetti, Francesco Puma, Roberta Lucchini, Stefano Santoprete, Roberto Cirocchi, Alessia Corsi, Roberta Triola, Nicola Avenia

Published online on: October 4, 2019
Open Access

Hypoxia modifies the polarization of macrophages and their inflammatory microenvironment, and inhibits malignant behavior in cancer cells

Xixian Ke, Cheng Chen, Yongxiang Song, Qingyong Cai, Jian Li, Yang Tang, Xu Han, Wendong Qu, Anping Chen, Hui Wang, Gang Xu, Daxing Liu

Published online on: October 3, 2019
Open Access

Insights on CXC chemokine receptor 2 in breast cancer: An emerging target for oncotherapy (Review)

Fengzhu Guo, Lang Long, Jiantao Wang, Yuyi Wang, Yanyang Liu, Li Wang, Feng Luo

Published online on: October 3, 2019
Open Access

Ewing's sarcoma in the spinal canal of T12‑L3: A case report and review of the literature

Dajun Yan, Jie Zhang, Dequan Zhong

Published online on: October 3, 2019
Open Access

Silencing of KCNK15‑AS1 inhibits lung cancer cell proliferation via upregulation of miR‑202 and miR‑370

Jun Peng, Xin‑Long Chen, Hong‑Zhong Cheng, Zhe‑Yuan Xu, Han Wang, Zhi‑Zhou Shi, Jun Liu, Xian‑Gu Ning, Hao Peng

Published online on: October 2, 2019
Open Access

Value of ultrasound combined with MRI in the diagnosis of primary and recurrent hepatocellular carcinoma

Xiaoli Ji, Shisheng Zhou, Peng Yang, Faqin Liu, Yan Li, Hong Li

Published online on: October 2, 2019

Novel sphingomyelin biomarkers for brain glioma and associated regulation research on the PI3K/Akt signaling pathway

Xiao‑Hui Zhai, Jian Xiao, Jie‑Kai Yu, Hong Sun, Shu Zheng

Published online on: October 2, 2019

Mitotically‑associated long non‑coding RNA promotes cancer cell proliferation in hepatocellular carcinoma by downregulating miR‑122a

Xuejing Zhang, Hongling Li, Mingfeng Mao, Xiangyang Wang, Jingjing Zheng, Shunshi Yang

Published online on: October 2, 2019
Open Access

The role of pyruvate kinase M2 in anticancer therapeutic treatments (Review)

Qiongli Su, Shengping Luo, Qiuhong Tan, Jun Deng, Sichun Zhou, Mei Peng, Ting Tao, Xiaoping Yang

Published online on: October 2, 2019
Open Access

Bioinformatics analysis of potential therapeutic targets among ARHGAP genes in breast cancer

Wei‑Xian Chen, Ming Lou, Lin Cheng, Qi Qian, Ling‑Yun Xu, Li Sun, Yu‑Lan Zhu, Hong Dai

Published online on: October 2, 2019
Open Access

Predictive values of miR‑129 and miR‑139 for efficacy on patients with prostate cancer after chemotherapy and prognostic correlation

Zhongchun Hu, Junjie Guo, Ming Zhao, Tao Jiang, Xiaofeng Yang

Published online on: October 2, 2019

Growth inhibitory effects of PC‑NSAIDs on human breast cancer subtypes in cell culture

Shelley Burge, Lenard M. Lichtenberger

Published online on: October 2, 2019
Open Access

Dendritic cells loaded with CD44+ CT‑26 colon cell lysate evoke potent antitumor immune responses

Changhao Fu, Ning Zhou, Yuanyuan Zhao, Jinyue Duan, Hao Xu, Yi Wang

Published online on: October 2, 2019
Open Access

A subset of patients with MSS/MSI‑low‑colorectal cancer showed increased CD8(+) TILs together with up‑regulated IFN‑γ

Tomohiro Kikuchi, Kosaku Mimura, Hirokazu Okayama, Yuko Nakayama, Katsuharu Saito, Leo Yamada, Eisei Endo, Wataru Sakamoto, Shotaro Fujita, Hisahito Endo, Motonobu Saito, Tomoyuki Momma, Zenichiro Saze, Shinji Ohki, Koji Kono

Published online on: October 2, 2019
Open Access

Metabolic tumor volume predicts overall survival in patients with primary pulmonary lymphoepithelioma‑like carcinoma

Chun‑Yu Lin, Yu‑Chuan Chang, I‑Ting Wang, Meng‑Heng Hsieh, Chih‑Wei Wang, Shu‑Min Lin, Ching‑Yang Wu, Yueh‑Fu Fang

Published online on: October 2, 2019
Open Access

Identification of core differentially methylated genes in glioma

Jing Xue, Hai‑Xia Gao, Wei Sang, Wen‑Li Cui, Ming Liu, Yan Zhao, Meng‑Bo Wang, Qian Wang, Wei Zhang

Published online on: October 2, 2019
Open Access

Expression of miR-23a and miR-135 and tumor markers in gastric cancer patients and the significance in diagnosis

Likui Yin, Guangxiao Xu, Yuntao Zhu, Yongqiang Wang

Published online on: October 1, 2019
Open Access

Data mining of the expression and regulatory role of BCAT1 in hepatocellular carcinoma

Haifan Zou, Minjun Liao, Wentao Xu, Renzhi Yao, Weijia Liao

Published online on: September 30, 2019
Open Access

Identification of key genes and evaluation of clinical outcomes in lung squamous cell carcinoma using integrated bioinformatics analysis

Yangfeng Shi, Yeping Li, Chao Yan, Hua Su, Kejing Ying

Published online on: September 30, 2019
Open Access

The core genes involved in the promotion of depression in patients with ovarian cancer

Yuexiong Yi, Yanyan Liu, Kejia Wu, Wanrong Wu, Wei Zhang

Published online on: September 30, 2019
Open Access

Use of immunotherapy in the treatment of gastric cancer (Review)

Luhong Yang, Yanxia Wang, Huafeng Wang

Published online on: September 30, 2019
Open Access

Bioinformatics analysis of Ewing's sarcoma: Seeking key candidate genes and pathways

Jinming Zhang, Yao Zhang, Ze Li, Hongzeng Wu, Jianjun Xun, Helin Feng

Published online on: September 30, 2019
Open Access

A nomogram to predict vascular invasion before resection of colorectal cancer

Weishun Xie, Jungang Liu, Xiaoliang Huang, Guo Wu, Franco Jeen, Shaomei Chen, Chuqiao Zhang, Wenkang Yang, Chan Li, Zhengtian Li, Lianying Ge, Weizhong Tang

Published online on: September 30, 2019
Open Access

Clinical value of ultrasonic imaging in diagnosis of hypopharyngeal cancer with cervical lymph node metastasis

Guzi Wang, Xiaoguang Li, Li Li, Dayu Liu, Ruijie Sun, Qiu Zhang, Chenchen Geng, Haitong Gong, Xiaoqian Gao

Published online on: September 30, 2019
Open Access

Abnormal accumulation of p53 predicts radioresistance leading to poor survival in patients with endometrial carcinoma

Azusa Akiyama, Takeo Minaguchi, Kaoru Fujieda, Yoshihiko Hosokawa, Keiko Nishida, Ayumi Shikama, Nobutaka Tasaka, Manabu Sakurai, Hiroyuki Ochi, Toyomi Satoh

Published online on: September 30, 2019
Open Access

Identification of biomarkers and construction of a microRNA‑mRNA regulatory network for ependymoma using integrated bioinformatics analysis

Biao Yang, Jun‑Xi Dai, Yuan‑Bo Pan, Yan‑Bin Ma, Sheng‑Hua Chu

Published online on: September 30, 2019

Hepatitis B virus infection and 1q21 amplification in multiple myeloma

Dan Guo, Peipei Xu, Chaoyang Guan, Yong Xu, Yonggong Yang, Jingyan Xu, Rongfu Zhou, Bing Chen

Published online on: September 27, 2019
Open Access

Identification of differentially expressed microRNAs and the potential of microRNA‑455‑3p as a novel prognostic biomarker in glioma

Wei Wang, Shuwen Mu, Qingshuang Zhao, Liang Xue, Shousen Wang

Published online on: September 27, 2019
Open Access

Deep learning techniques for detecting preneoplastic and neoplastic lesions in human colorectal histological images

Paola Sena, Rita Fioresi, Francesco Faglioni, Lorena Losi, Giovanni Faglioni, Luca Roncucci

Published online on: September 27, 2019
Open Access

High efficacy and safety of VTD as an induction protocol in patients with newly diagnosed multiple myeloma eligible for high dose therapy and autologous stem cell transplantation: A report of the Polish Myeloma Study Group

Iwona Hus, Joanna Mańko, Dariusz Jawniak, Artur Jurczyszyn, Grzegorz Charliński, Katarzyna Poniewierska‑Jasak, Lidia Usnarska‑Zubkiewicz, Mateusz Sawicki, Agnieszka Druzd‑Sitek, Alina Świderska, Anna Kopińska, Norbert Grząśko, Małgorzata Raźny, Aleksandra Wędłowska, Aleksander Perzyński, Aleksandra Gałązka, Dominik Dytfeld, Tadeusz Kubicki, Marek Rodzaj, Anna Waszczuk‑Gajda, Joanna Drozd‑Sokołowska, Bartłomiej Pogłódek, Anna Pasternak, Monika Długosz‑Danecka, Agnieszka Szymczyk, Anna Dmoszyńska

Published online on: September 27, 2019
Open Access

[Corrigendum] A germline alteration of ERBB2 increases the risk of breast cancer in Chinese Han women with a familial history of malignant tumors

Yan Ju, Lifeng Wang, Shengjun Ta, Rui Shu, Shanling Yang, Xican Gao, Hongping Song, Liwen Liu

Published online on: September 27, 2019

Novel serum markers HSP60, CHI3L1, and IGFBP-2 in metastatic colorectal cancer

Michal Vocka, Daniel Langer, Vladimir Fryba, Jaromir Petrtyl, Tomas Hanus, Marta Kalousova, Tomas Zima, Lubos Petruzelka

Published online on: September 26, 2019
Open Access

lncRNA AWPPH promotes the migration and invasion of glioma cells by activating the TGF‑β pathway

Bin Dai, Zhiyong Xiao, Beibei Mao, Guangtong Zhu, Hui Huang, Feng Guan, Haiyang Su, Zhenyang Lin, Weicheng Peng, Zhiqiang Hu

Published online on: September 25, 2019
Open Access

Expression of the Sonic Hedgehog pathway components in clear cell renal cell carcinoma

Anna Kotulak‑Chrzaszcz, Jakub Klacz, Marcin Matuszewski, Zbigniew Kmiec, Piotr M. Wierzbicki

Published online on: September 25, 2019
Open Access

Integrated analysis of lncRNA CTD‑2357A8.3 expression and its potential roles in head and neck squamous cell carcinoma

Bo Zou, Xin Guan, Wen Zhang, Dong Wang, Kai Xu, Dao‑Ying Yuan, Zhen Meng, Bin Zhang

Published online on: September 25, 2019
Open Access

PLCB4 upregulation is associated with unfavorable prognosis in pediatric acute myeloid leukemia

Shiwen Wu, Wei Zhang, Dongqin Shen, Jianle Lu, Li Zhao

Published online on: September 25, 2019
Open Access

Identification of the lncRNA‑miRNA‑mRNA network associated with gastric cancer via integrated bioinformatics analysis

Xiao‑Yu Ma, Yu Ma, Huan Zhou, Hui‑Jing Zhang, Ming‑Jun Sun

Published online on: September 25, 2019
Open Access

Interleukin 1 receptor antagonist gene variable number of tandem repeats polymorphism and cutaneous melanoma

Sabina Cauci, Cinzia Buligan, Francesco Rocchi, Ilaria Salvador, Luigi Xodo, Giuseppe Stinco

Published online on: September 25, 2019
Journal Cover

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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