Early Online

Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng

Published online on: July 8, 2020
Open Access

USP9X promotes the proliferation, invasion and metastasis of liver cancer cells through regulating the JAK2/STAT3 signaling

Xingchao Song, Weibin Yang, Chao Wu, Yamin Han, Yaowu Lu

Published online on: July 8, 2020
Open Access

Establishment of highly invasive pancreatic cancer cell lines and the expression of IL‑32

Kohji Takagi, Johji Imura, Akiko Shimomura, Akira Nocuchi, Takashi Minamisaka, Shinichi Tanaka, Takeshi Nishida, Hideki Hatta, Takahiko Nakajima

Published online on: July 8, 2020
Open Access

Long non‑coding RNA BCAR4 promotes liver cancer progression by regulating proliferation, migration and invasion

Aiyao Wang, Jun Meng, Hui Liu, Chen Li, Zhiyong Zhou

Published online on: July 8, 2020
Open Access

Expression of miR-129-5p and miR-433 in the serum of breast cancer patients and their relationship with clinicopathological features

Jinhui Xue, Xiaohan Zhu, Pei Huang, Yingying He, Yanjing Xiao, Ruihan Liu, Min Zhao

Published online on: July 8, 2020
Open Access

High S phase kinase‑associated protein 2 expression is a potential prognostic biomarker for glioma

Zhi‑Jian Cheng, Hong‑Qing Cai, Min‑Jie Zhang, Yi Zhong, Jie He, Qing Yuan, Jia‑Jie Hao, Ming‑Rong Wang, Jing‑Hai Wan

Published online on: July 7, 2020
Open Access

Prognostic value of CXCL17 and CXCR8 expression in patients with colon cancer

Hongyan Yao, Yufeng Lv, Xuefeng Bai, Zhaojin Yu, Xiaojian Liu

Published online on: July 7, 2020

Long non‑coding RNA‑ZNF281 upregulates PTEN expression via downregulation of microRNA‑221 in non‑small cell lung cancer

Xin Lu, Bin Yin, Xuekun Wang, Fengchan Wang, Yue Li, Na Wang, Xinai Yang, Wenqing Jiang

Published online on: July 7, 2020
Open Access

Adenovirus‑mediated overexpression of interleukin‑21 regulates the development of oral squamous cell carcinoma in vitro

Hao Liu, Peng Liu, Di Sun, Dayuan Xing, Xiaoping Wang, Jinge Yang, Shengzhi Wang

Published online on: July 7, 2020

Quantitative volumetric assessment of the solid portion percentage on CT images to predict ROS1/ALK rearrangements in lung adenocarcinomas

Jing Zheng, Jianya Zhou, Jinpeng Liu, Jingfeng Xu, Ke  Sun, Bo  Wang, He Cao, Wei Ding, Jianying Zhou

Published online on: July 6, 2020
Open Access

Effects of aspirin on the gastrointestinal tract: Pros vs. cons (Review)

Zhuoya Li, Zheng Wang, Baile Shen, Chen Chen, Xiaoyun Ding, Haojun Song

Published online on: July 6, 2020
Open Access

xCT inhibitor sulfasalazine depletes paclitaxel‑resistant tumor cells through ferroptosis in uterine serous carcinoma

Akiko Sugiyama, Tsuyoshi Ohta, Miyuki Obata, Kanako Takahashi, Manabu Seino, Satoru Nagase

Published online on: July 6, 2020
Open Access

Correlation of APE1 with VEGFA and CD163+ macrophage infiltration in bladder cancer and their prognostic significance

Lin-Ang Wang, Bo Yang, Tang Tang, Yuxin Yang, Dianzheng Zhang, Hualiang Xiao, Jing Xu, Luofu Wang, Li Lin, Jun Jiang

Published online on: July 6, 2020
Open Access

High expression of endothelial progenitor cell‑induced angiogenic markers is associated with bile acid levels in HCC

Jiang‑Long Chen, Long Wang, Rong Li, Ying‑Fu Jiao, Wei‑Feng Yu

Published online on: July 6, 2020

Characterization and imaging of surgical specimens of invasive breast cancer and normal breast tissues with the application of Raman spectral mapping: A feasibility study and comparison with randomized single‑point detection method

Haipeng Zhang, Xiaozhen Wang, Rongbo Ding, Lishengnan Shen, Pin Gao, Hui Xu, Caifeng Xiu, Huanxia Zhang, Dong Song, Bing Han

Published online on: July 3, 2020
Open Access

Effect of CEACAM6 silencing on the biological behavior of human gallbladder cancer cells

Chengming Tian, Bingye Zhang, Chunlin Ge

Published online on: July 3, 2020
Open Access

Research progress regarding the role of long non‑coding RNAs in osteosarcoma (Review)

Yanli Zhang, Yanchuan Pu, Jin Wang, Zicai Li, Hulin Wang

Published online on: July 3, 2020
Open Access

miR‑502‑5p inhibits the proliferation, migration and invasion of gastric cancer cells by targeting SP1

Xiaobo Peng, Meihong Wu, Wuxia Liu, Chengtao Guo, Lixing Zhan, Xianbao Zhan

Published online on: July 3, 2020

Long non‑coding RNA GAS5 in human cancer (Review)

Xiaoyan Yang, Zhizhong Xie, Xiaoyong Lei, Runliang Gan

Published online on: July 3, 2020
Open Access

Telomerase inhibition decreases esophageal squamous carcinoma cell migration and invasion

Jiayan Li, Guogang Dong, Jinyun Song, Guolei Tan, Xuping Wu

Published online on: July 3, 2020
Open Access

Tumor budding index and microvessel density assessment in patients with endometrial cancer: A pilot study

Tomasz Kluz, Tomasz Łoziński, Sylwia Czekierdowska, Norbert Stachowicz, Grzegorz Gurynowicz, Mieczysław Chróściel, Artur Czekierdowski

Published online on: July 3, 2020
Open Access

Systemic inflammatory indices predict tumor response to neoadjuvant chemoradiotherapy for locally advanced rectal cancer

Sicong Lai, Liang Huang, Shuangling Luo, Zhanzhen Liu, Jianghui Dong, Liping Wang, Liang Kang

Published online on: July 3, 2020
Open Access

Konjac glucomannan reverses multi‑drug resistance of HepG2/5‑FU cells by suppressing AKT signaling and increasing p53 expression

Bin Chen, Xin Xu, Ke Zheng, Ling Liu, Yijun Yu, Ying Xin

Published online on: July 1, 2020
Open Access

MicroRNA‑101 suppresses colorectal cancer progression by negative regulation of Rap1b

Zhiyuan Zhou, Hang Xu, Yantao Duan, Bin Liu

Published online on: July 1, 2020
Open Access

Stanniocalcin 1 is a prognostic biomarker in glioma

Weijian Luo, Dong Chen, Hao Wang, Jiliang Hu

Published online on: July 1, 2020

Biomarker phenotyping drives clinical management in axillary sentinel node: A retrospective study on women with primary breast cancer in 2002

Sergio Diotaiuti, Simona De Summa, Rosanna  Altieri, Caterina  Dantona, Stefania  Tommasi, Maria  Di Gennaro, Giuseppe  Rubini, Maria   Irene Pastena, Antonella  Argentiero, Francesco   Alfredo Zito, Nicola  Silvestris, Angelo   Virgilio Paradiso

Published online on: July 1, 2020
Open Access

Knockdown of m6A methyltransferase METTL3 in gastric cancer cells results in suppression of cell proliferation

Li Jiang, Ting Chen, Li Xiong, Ji‑Hao Xu, Ai‑Yu Gong, Bin Dai, Ganlin Wu, Kenny Zhu, Eugene Lu, Nicholas William Mathy, Xian‑Ming Chen

Published online on: July 1, 2020
Open Access

Effect of KRAS and NRAS mutations on the prognosis of patients with synchronous metastatic colorectal cancer presenting with liver‑only and lung‑only metastases

Shih‑Chang Chuang, Ching‑Wen Huang, Yi‑Ting Chen, Cheng‑Jen Ma, Hsiang‑Lin Tsai, Tsung‑Kun Chang, Wei‑Chih Su, Wen‑Hung Hsu, Chao‑Hung Kuo, Jaw‑Yuan Wang

Published online on: July 1, 2020
Open Access

Downregulation of microRNA‑126 is inversely correlated with insulin receptor substrate‑1 protein expression in colorectal cancer and is associated with advanced stages of disease

Shicai Ye, Caiyuan Yu, Guixia Zhang, Feixiong Shi, Yongze  Chen, Jianyun Yang, Weiyun Wu, Yu Zhou

Published online on: July 1, 2020
Open Access

PAK6 promotes cervical cancer progression through activation of the Wnt/β‑catenin signaling pathway

Qin Yang, Yingchao Zhao, Yeshan Chen, Yu Chang, Ai Huang, Tie Xu, Guiling Li, Gang Wu

Published online on: July 1, 2020
Open Access

Identification of a five‑gene signature for predicting the progression and prognosis of stage I endometrial carcinoma

Jia Bian, Yuzi Xu, Fei Wu, Qiangwei Pan, Yunlong Liu

Published online on: July 1, 2020
Open Access

DNA mismatch repair is not disrupted in stage 0 colorectal cancer resected using endoscopic submucosal dissection

Tomohiro Sugiyama, Moriya Iwaizumi, Masanao Kaneko, Shinya Tani, Mihoko Yamade, Yasushi Hamaya, Takahisa Furuta, Hiroaki Miyajima, Satoshi Osawa, Satoshi Baba, Masato Maekawa, Ken Sugimoto

Published online on: July 1, 2020
Open Access

Circular RNA profiling in plasma exosomes from patients with gastric cancer

Min Rao, Yonggang Zhu, Lingzhi Qi, Feng Hu, Pujun Gao

Published online on: July 1, 2020
Open Access

Genistein inhibits lung cancer cell stem‑like characteristics by modulating MnSOD and FoxM1 expression

Zhimin Fu, Xiaocheng Cao, Lihua Liu, Xiaozheng Cao, Yinghong Cui, Xiang Li, Meifang Quan, Kaiqun Ren, A Chen, Chang Xu, Yebei Qiu, Xiangding Chen, Zheng Wang, Jianguo Cao

Published online on: July 1, 2020
Open Access

Small RNA profiles of HTLV‑1 asymptomatic carriers with monoclonal and polyclonal rearrangement of the T‑cell antigen receptor γ‑chain using massively parallel sequencing: A pilot study

Daniela Raguer Valadão De Souza, Rodrigo Pessôa, Andrezza Nacimento, Youko Nukui, Juliana Pereira, Jorge Casseb, Augusto César Penalva De Oliveira, Alberto José Da Silva Duarte, Patricia Bianca Clissa, Sabri Saeed Sanabani

Published online on: July 1, 2020

Clinical management of extrapleural septal solitary fibrous tumor: A case report

Michele Cavaliere, Eva Piro, Massimo Mascolo, Claudio Di Nola, Salvatore Allosso, Antonella M. Di Lullo, Gaetano Motta, Maurizio Iengo, Elena Cantone

Published online on: June 30, 2020
Open Access

Use of peripheral blood transcriptomic biomarkers to distinguish high‑grade cervical squamous intraepithelial lesions from low‑grade lesions

Cunhua Zou, Yali Lyu, Jing Jiang, Yuan Cao, Min Wang, Changmei Sang, Ruirui  Zhang, Haifeng Li, Choong‑Chin Liew, Changming Cheng, Shuping Zhao

Published online on: June 26, 2020
Open Access

An optimal prognostic model based on gene expression for clear cell renal cell carcinoma

Dan Xu, Wantai Dang, Shaoqing Wang, Bo Hu, Lianghong Yin, Baozhang Guan

Published online on: June 26, 2020
Open Access

Potential five‑mRNA signature model for the prediction of prognosis in patients with papillary thyroid carcinoma

Lin‑Kun Zhong, Xiao‑Xiong Gan, Xing‑Yan Deng, Fei Shen, Jian‑Hua Feng, Wen‑Song Cai, Qiong‑Yao Liu, Jian‑Hang Miao, Bing‑Xing Zheng, Bo Xu

Published online on: June 26, 2020
Open Access

Mutation analysis and genomic imbalances of cells found in effusion fluids from patients with ovarian cancer

Marta Brunetti, Ioannis Panagopoulos, Ilyá Kostolomov, Ben Davidson, Sverre Heim, Francesca Micci

Published online on: June 26, 2020

Enhancement of piperlongumine chemosensitivity by silencing heme oxygenase‑1 expression in cholangiocarcinoma cell lines

Chutima Talabnin, Krajang Talabnin, Sopit Wongkham

Published online on: June 26, 2020
Open Access

Increase in CD4+FOXP3+ regulatory T cell number and upregulation of the HGF/c‑Met signaling pathway during the liver metastasis of colorectal cancer

Xiaoming Huang, Zexian Chen, Nanrong Zhang, Caiyan Zhu, Xutao Lin, Jiandong Yu, Zhiping Chen, Ping Lan, Yunle Wan

Published online on: June 26, 2020
Open Access

Primary intradural extramedullary Ewing sarcoma: A case report and literature review

Yuya Izubuchi, Hideaki Nakajima, Kazuya Honjoh, Yoshiaki Imamura, Takayuki Nojima, Akihiko Matsumine

Published online on: June 26, 2020
Open Access

High expression of GPNMB indicates an unfavorable prognosis in glioma: Combination of data from the GEO and CGGA databases and validation in tissue microarray

Xiao Feng, Lina Zhang, Shanbao Ke, Tao Liu, Liuwei  Hao, Pan Zhao, Wenzhi Tu, Shundong Cang

Published online on: June 26, 2020
Open Access

γ‑H2AX as a potential indicator of radiosensitivity in colorectal cancer cells

Satoshi Kawashima, Nao Kawaguchi, Kohei Taniguchi, Keitaro Tashiro, Kazumasa Komura, Tomohito Tanaka, Yosuke Inomata, Yoshiro Imai, Ryo Tanaka, Masashi Yamamoto, Yoshihiro Inoue, Sang‑Woong Lee, Masaru Kawai, Keitaro Tanaka, Junji Okuda, Kazuhisa Uchiyama

Published online on: June 26, 2020
Open Access

Prognostic potential of lncRNA RHPN1-AS1 in glioma

Yong Wu, Wuting Wei, Linjun Tang, Liangwei Wang

Published online on: June 25, 2020
Open Access

Immune disorder in endometrial cancer: Immunosuppressive microenvironment, mechanisms of immune evasion and immunotherapy (Review)

Lei Zhan, Xiaojing Liu, Jing Zhang, Yunxia Cao, Bing Wei

Published online on: June 25, 2020
Open Access

CAF‑1/p150 promotes cell proliferation, migration, invasion and predicts a poor prognosis in patients with cervical cancer

Shu Yang, Qian Long, Min Chen, Xiao Liu , Hang Zhou

Published online on: June 25, 2020
Open Access

Prognostic and predictive value of monocarboxylate transporter 4 in patients with breast cancer

Sheng Xiao, Hongjia Zhu, Yujun Shi, Zhenru Wu, Hegang Wu, Mingjun Xie

Published online on: June 25, 2020
Open Access

Limb‑bud and heart as a novel biomarker for gastric intestinal type adenocarcinoma

Shu‑Sheng Wu, Jian Chen, Ying Yan, Hui‑Qin Luo, Wen‑Ju Chen, Yi‑Fu He

Published online on: June 25, 2020
Open Access

Bioinformatics analysis of aberrantly expressed exosomal lncRNAs in oral squamous cell carcinoma (CAL‑27 vs. oral epithelial) cells

Jiajia Jin, Zixiao Huang, Xiaoyan Lu, Shengrong Wu, Mei'e Jia, Xin Li, Zhiyong Li, Xiangyi He

Published online on: June 24, 2020
Open Access

miR‑429 inhibits osteosarcoma progression by targeting HOXA9 through suppressing Wnt/β‑catenin signaling pathway

Liangzhi Sun, Libo Wang, Suxian Luan, Yanzhou Jiang, Qiang Wang

Published online on: June 24, 2020

ANGPTL4 overexpression is associated with progression and poor prognosis in breast cancer

Jing Zhao, Juntian Liu, Nan Wu, Hailian Zhang, Shichao Zhang, Lijuan Li, Meng Wang

Published online on: June 24, 2020
Open Access

LncRNA MEG3 inhibits non‑small cell lung cancer via interaction with DKC1 protein

Zhi Yang, Zitong Wang, Yong Duan

Published online on: June 24, 2020
Open Access

Timing of breast cancer surgery during the menstrual cycle‑is there an optimal time of the month? (Review)

Sarah M. Bernhardt, Pallave Dasari, David Walsh, Amanda R. Townsend, Timothy J. Price, Wendy V. Ingman

Published online on: June 24, 2020
Open Access

Relationship between the immunohistological examination and fluorescence visualization of oral squamous cell carcinoma

Keisuke Sugahara, Yu Koyama, Masahide Koyachi, Satoru Matsunaga, Kento Odaka, Kei Kitamura, Kei Nakajima, Kenichi Matsuzaka, Shinichi Abe, Akira Katakura

Published online on: June 24, 2020
Open Access

Cervical cancer in low and middle‑income countries (Review)

Rodney Hull, Mzwandile Mbele, Tshepiso Makhafola, Chindo Hicks, Shao‑Ming Wang, Rui Manuel Reis, Ravi Mehrotra, Zilungile Mkhize‑Kwitshana, Gibson Kibiki, David O. Bates, Zodwa Dlamini

Published online on: June 19, 2020
Open Access

Diagnostic value and prognostic significance of LI‑cadherin and miR‑378e in colorectal cancer

Xujie Wang, Zhihua Li, Jixin Fu, Weiwei Xu, Zongxian Li

Published online on: June 19, 2020
Open Access

Regorafenib treatment outcome for Taiwanese patients with metastatic gastrointestinal stromal tumors after failure of imatinib and sunitinib: A prospective, non‑randomized, single‑center study

Chia‑Hsiang Hu, Chun‑Nan Yeh, Jen‑Shi Chen, Chun‑Yi Tsai, Shang‑Yu Wang, Chi‑Tung Cheng, Ta‑Sen Yeh

Published online on: June 19, 2020
Open Access

Interferon‑γ induced PD‑L1 expression and soluble PD‑L1 production in gastric cancer

Yushi Imai, Tetsuhiro Chiba, Takayuki Kondo, Hiroaki Kanzaki, Kengo  Kanayama, Junjie  Ao, Ryuta Kojima, Yuko Kusakabe, Masato  Nakamura, Tomoko  Saito, Ryo Nakagawa, Eiichiro Suzuki, Shingo Nakamoto, Ryosuke  Muroyama, Akinobu Tawada, Tomoaki Matsumura, Tomoo  Nakagawa, Jun Kato, Ai Kotani, Hisahiro Matsubara, Naoya Kato

Published online on: June 19, 2020
Open Access

Lenvatinib prolongs the progression‑free survival time of patients with intermediate‑stage hepatocellular carcinoma refractory to transarterial chemoembolization: A multicenter cohort study using data mining analysis

Shigeo Shimose, Takumi Kawaguchi, Masatoshi Tanaka, Hideki Iwamoto, Ken Miyazaki, Etsuko Moriyama, Hiroyuki Suzuki, Takashi Niizeki, Tomotake Shirono, Masahito Nakano, Hideya Suga, Taizo Yamaguchi, Yoshinori Yokokura, Kazunori Noguchi, Hironori Koga, Takuji Torimura

Published online on: June 19, 2020
Open Access

Value of shear wave elastography in the diagnosis and evaluation of cervical cancer

Bing Fu, Hong Zhang, Zhen‑Wei Song, Ji‑Xiang Lu, Shi‑Hui Wu, Jie Li

Published online on: June 19, 2020

ERK‑mediated negative feedback regulation of oncogenic EGFRvIII in glioblastoma cells

Ratna Dini Haryuni, Tomohiro Tanaka, Yue Zhou, Satoru Yokoyama, Hiroaki Sakurai

Published online on: June 19, 2020
Open Access

Synthetic MUC1 breast cancer vaccine containing a Toll‑like receptor 7 agonist exerts antitumor effects

Yu Liu, Li Tang, Ningning Gao, Yuwen Diao, Jingjing Zhong, Yongqiang Deng, Zhulin Wang, Guangyi Jin, Xiaodong Wang

Published online on: June 19, 2020
Open Access

Mechanistic studies of cytotoxic activity of the mesoionic compound MIH 2.4Bl in MCF‑7 breast cancer cells

Luciana Amaral De Mascena Costa, Dipti Debnath, Ashlyn C. Harmon, Silvany De Sousa Araújo, Helivaldo Diógenes Da Silva Souza, Petrônio Filgueiras De Athayde Filho, Aurea Wischral, Manoel Adrião Gomes Filho, J. Michael Mathis

Published online on: June 19, 2020
Journal Cover

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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