Primary hematological malignancy of the uterine cervix: A case report

  • Authors:
    • Wei Gui
    • Jing Li
    • Zong Zhang
    • Lieyang Wang
    • Jin Zhao
    • Li Ma
    • Liping Su
  • View Affiliations

  • Published online on: July 22, 2019     https://doi.org/10.3892/ol.2019.10652
  • Pages: 3337-3341
  • Copyright: © Gui et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The present case report investigated the clinical characteristics of primary hematological malignancy of the uterine cervixin five patients. Among the five patients, three patients were diagnosed with non-Hodgkin's lymphoma (NHL) and two patients with myeloid sarcoma (MS) of the uterine cervix. Biopsies of the uterine cervices demonstrated the involvement of lymphoid cells or myeloid blasts cells. Immunohistochemical staining demonstrated the expression of B-lymphoid and myeloid lineage markers. The associated lysozyme, myeloperoxidase and mast/stem cell growth factor receptor (CD117) markers were specific for the diagnosis of MS. The three patients with NHL survived, and one of the patients survived for 82 months with no evidence of disease; however, was eventually lost to follow‑up. The two patients with MS succumbed to the cancer as a result of progressive disease and leukemia. Therefore, pathological examination may be important for the timely diagnosis and appropriate therapeutic regimen for primary hematological malignancy of the uterine cervix.

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September 2019
Volume 18 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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APA
Gui, W., Li, J., Zhang, Z., Wang, L., Zhao, J., Ma, L., & Su, L. (2019). Primary hematological malignancy of the uterine cervix: A case report. Oncology Letters, 18, 3337-3341. https://doi.org/10.3892/ol.2019.10652
MLA
Gui, W., Li, J., Zhang, Z., Wang, L., Zhao, J., Ma, L., Su, L."Primary hematological malignancy of the uterine cervix: A case report". Oncology Letters 18.3 (2019): 3337-3341.
Chicago
Gui, W., Li, J., Zhang, Z., Wang, L., Zhao, J., Ma, L., Su, L."Primary hematological malignancy of the uterine cervix: A case report". Oncology Letters 18, no. 3 (2019): 3337-3341. https://doi.org/10.3892/ol.2019.10652