Journal Articles

Open Access

Mitochondrial oncobioenergetics of prostate tumorigenesis (Review)

Praveen Kumar Vayalil

Pages: 4367-4376 Published online on: 27 August 2019
Open Access

Sonic Hedgehog signaling pathway as a potential target to inhibit the progression of hepatocellular carcinoma (Review)

Kuo‑Shyang Jeng, Chi‑Juei Jeng, Wen‑Juei Jeng, I‑Shyan Sheen, Shih‑Yun Li, Chuen‑Miin Leu, Yeou‑Guang Tsay, Chiung‑Fang Chang

Pages: 4377-4384 Published online on: 09 September 2019
Open Access

Role of circular RNA in hematological malignancies (Review)

Mei Mei, Yingjun Wang, Zhaoming Li, Mingzhi Zhang

Pages: 4385-4392 Published online on: 10 September 2019
Open Access

Molecular mechanisms of TUG1 in the proliferation, apoptosis, migration and invasion of cancer cells (Review)

Hui Zhou, Lina Sun, Fusheng Wan

Pages: 4393-4402 Published online on: 10 September 2019
Open Access

Dauricine suppresses the growth of pancreatic cancer in vivo by modulating the Hedgehog signaling pathway

Ying‑Bo Zhang, Hong‑Xin Fei, Jia Guo, Xiao‑Jie Zhang, Shu‑Liang Wu, Li‑Li Zhong

Pages: 4403-4414 Published online on: 03 September 2019
Open Access

CAR‑T 19 combined with reduced‑dose PD‑1 blockade therapy for treatment of refractory follicular lymphoma: A case report

Jia Wang, Qi Deng, Yan‑Yu Jiang, Rui Zhang, Hai‑Bo Zhu, Juan‑Xia Meng, Yu‑Ming Li

Pages: 4415-4420 Published online on: 27 August 2019
Open Access

STAMBPL1 knockdown has antitumour effects on gastric cancer biological activities

Da‑Jun Yu, Jun Qian, Xin Jin, Jing Li, Chen‑Xu Guo, Xi‑Cheng Yue

Pages: 4421-4428 Published online on: 03 September 2019
Open Access

Identification of key biomarkers and potential molecular mechanisms in lung cancer by bioinformatics analysis

Zhenhua Li, Meixiang Sang, Ziqiang Tian, Zhao Liu, Jian Lv, Fan Zhang, Baoen Shan

Pages: 4429-4440 Published online on: 04 September 2019
Open Access

Survival‑related risk score of lung adenocarcinoma identified by weight gene co‑expression network analysis

He Wang, Di Lu, Xiguang Liu, Jianjun Jiang, Siyang Feng, Xiaoying Dong, Xiaoshun Shi, Hua Wu, Gang Xiong, Haofei Wang, Kaican Cai

Pages: 4441-4448 Published online on: 04 September 2019
Open Access

Extracellular AGR3 regulates breast cancer cells migration via Src signaling

Joanna Obacz, Lucia Sommerova, Daria Sicari, Michal Durech, Tony Avril, Filippo Iuliano, Silvia Pastorekova, Roman Hrstka, Eric Chevet, Frederic Delom, Delphine Fessart

Pages: 4449-4456 Published online on: 10 September 2019
Open Access

Phenotype of mesenchymal stem cells from patients with myelodyplastic syndrome maybe partly modulated by decitabine

Yanbin Pang, Suxia Geng, Hongyang Zhang, Peilong Lai, Pengjun Liao, Lingji Zeng, Zesheng Lu, Jianyu Weng, Xin Du

Pages: 4457-4466 Published online on: 03 September 2019
Open Access

Plasma exosome‑encapsulated microRNA‑21 and microRNA‑92a are promising biomarkers for the prediction of peritoneal recurrence in patients with gastric cancer

Naruyoshi Soeda, Hisae Iinuma, Yusuke Suzuki, Daisuke Tsukahara, Hironori Midorikawa, Yuichi Igarashi, Yoshimasa Kumata, Masahiro Horikawa, Takashi Kiyokawa, Takeo Fukagawa, Ryoji Fukushima

Pages: 4467-4480 Published online on: 04 September 2019
Open Access

Distinct expression pattern and prognostic values of pituitary tumor transforming gene family genes in non‑small cell lung cancer

Shaolong Yang, Xiaodi Wang, Jingxing Liu, Bisha Ding, Kairi Shi, Jing Chen, Weiyang Lou

Pages: 4481-4494 Published online on: 10 September 2019
Open Access

Generation and identification of a thyroid cancer cell line with stable expression of CCDC67 and luciferase reporter genes

Lele Zhang, Longlong Wang, Mengyuan Lei, Runsheng Ma, Fangqin Yu, Chenguang Liu, Detao Yin

Pages: 4495-4502 Published online on: 10 September 2019
Open Access

Integrated genomic and methylation profile analysis to identify candidate tumor marker genes in patients with colorectal cancer

Guojun Huang, Wang Cheng, Fu Xi

Pages: 4503-4514 Published online on: 04 September 2019
Open Access

AKR1C1‑3, notably AKR1C3, are distinct biomarkers for liver cancer diagnosis and prognosis: Database mining in malignancies

Shou‑Feng Zhao, Shu‑Guo Wang, Zi‑Yun Zhao, Wen‑Li Li

Pages: 4515-4522 Published online on: 04 September 2019
Open Access

Prognostic value of pre‑treatment peripheral blood markers in pancreatic ductal adenocarcinoma and their association with S100A4 expression in tumor tissue

Hua Li, Xiangdong Tian, Yong Xu, Yi Pan, Yubei Huang, Dejun Zhou, Zhenguo Song

Pages: 4523-4534 Published online on: 05 September 2019
Open Access

Prognostic significance of mRNA expression of CASPs in gastric cancer

Zixiang Wang, Fubiao Ni, Fangyi Yu, Zhonghui Cui, Xiandong Zhu, Jicai Chen

Pages: 4535-4554 Published online on: 05 September 2019
Open Access

Association between polymorphisms in EGFR and tumor response during cetuximab and oxaliplatin‑based combination therapy in metastatic colorectal cancer: Analysis of data from two clinical trials

Hiromichi Maeda, Shoichi Hazama, Shigeyoshi Iwamoto, Koji Oba, Ryouichi Tsunedomi, Naoko Okayama, Yutaka Suehiro, Takahiro Yamasaki, Yuki Nakagami, Nobuaki Suzuki, Hiroaki Nagano, Junichi Sakamoto, Hideyuki Mishima, Naoki Nagata

Pages: 4555-4562 Published online on: 29 August 2019
Open Access

Pancreatoduodenectomy with portal vein resection favors the survival time of patients with pancreatic ductal adenocarcinoma: A propensity score matching analysis

Zhi‑Bo Xie, Ji Li, Ji‑Chun Gu, Chen Jin, Cai‑Feng Zou, De‑Liang Fu

Pages: 4563-4572 Published online on: 06 September 2019
Open Access

Expression of ALDH1A1 and CD133 is associated with the prognosis and effect of different chemotherapeutic regimens in gastric cancer

Wan‑Ting Liu, Wen‑Bo Liu, Min Gao, Yi‑Yin Zhang, Kang‑Sheng Gu

Pages: 4573-4582 Published online on: 04 September 2019
Open Access

Screening and authentication of molecular markers in malignant glioblastoma based on gene expression profiles

Yang‑Fan Zou, Ling‑Bing Meng, Zhao‑Kai He, Chen‑Hao Hu, Meng‑Jie Shan, Deng‑Yuan Wang, Xin Yu

Pages: 4593-4604 Published online on: 04 September 2019
Open Access

MicroRNA‑152 suppresses cisplatin resistance in A549 cells

Wenfei Zhao, Hongyun Li, Shanshan Yang, Di Guo, Jing Chen, Shaoyi Miao, Yi Xin, Miaomiao Liang

Pages: 4613-4620 Published online on: 10 September 2019
Open Access

miR-650 promotes non-small cell lung cancer cell proliferation and invasion by targeting ING4 through Wnt-1/β-catenin pathway

Xiangqin Tang, Yanjun Ding, Xiaoqing Wang, Xiuzhen Wang, Lin Zhao, Hongmei Bi

Pages: 4621-4628 Published online on: 04 September 2019
Open Access

NRP‑1 and KDR polymorphisms are associated with survival time in patients with advanced gastric cancer

Yue‑Jian Zhuo, Yu Shi, Tao Wu

Pages: 4629-4638 Published online on: 10 September 2019
Open Access

Long non‑coding RNA GATA6‑AS inhibits gastric cancer cell proliferation by downregulating microRNA‑25‑3p

Dingyun Li, Ting Wang, Jiajun Lai, Tao Zhang, Xiaofeng Zhu, Deqiang Zeng, Zhiwei Hu

Pages: 4639-4644 Published online on: 04 September 2019
Open Access

Cancer‑associated fibroblast stimulates cancer cell invasion in an interleukin‑1 receptor (IL‑1R)‑dependent manner

Xianglan Zhang, Young Sun Hwang

Pages: 4645-4650 Published online on: 27 August 2019
Open Access

Regulating the CCNB1 gene can affect cell proliferation and apoptosis in pituitary adenomas and activate epithelial‑to‑mesenchymal transition

Bin Li, Hai‑Bo Zhu, Gui‑Dong Song, Jian‑Hua Cheng, Chu‑Zhong Li, Ya‑Zhuo Zhang, Peng Zhao

Pages: 4651-4658 Published online on: 10 September 2019
Open Access

Ubiquitin ligase RNF5 serves an important role in the development of human glioma

Yong Gao, Chengmin Xuan, Mingwei Jin, Qi An, Baobiao Zhuo, Xincheng Chen, Lei Wang, Yuan Wang, Qingzeng Sun, Yingchun Shi

Pages: 4659-4666 Published online on: 04 September 2019
Open Access

Screening and identification of key biomarkers in adrenocortical carcinoma based on bioinformatics analysis

Zengmiao Xing, Zuojie Luo, Haiyan Yang, Zhenxing Huang, Xinghuan Liang

Pages: 4667-4676 Published online on: 06 September 2019
Open Access

Construction of a model to predict the prognosis of patients with cholangiocarcinoma using alternative splicing events

Hua‑Yu Wu, Yi Wei, Li‑Min Liu, Zhong‑Biao Chen, Qi‑Ping Hu, Shang‑Ling Pan

Pages: 4677-4690 Published online on: 10 September 2019
Open Access

High expression level of peptidylprolyl isomerase A is correlated with poor prognosis of liver hepatocellular carcinoma

Shilong Wang, Minghuan Li, Ligang Xing, Jinming Yu

Pages: 4691-4702 Published online on: 10 September 2019
Open Access

Preoperative color Doppler ultrasonography predicts early recurrence in AFP‑positive hepatocellular carcinoma

Miao Chen, Duo Wang, Yuan Zhao, Dan‑Mei Lu, Hong‑Xue Li, Jun‑Jie Liu, Hang Li

Pages: 4703-4711 Published online on: 09 September 2019
Open Access

STMN1 accumulation is associated with dysplastic and neoplastic lesions in patients with ulcerative colitis

Katsuya Osone, Takehiko Yokobori, Chika Katayama, Ryo Takahashi, Ryuji Kato, Hironori Tatsuski, Takahiro Takada, Reina Yajima, Yoko Motegi, Hiroomi Ogawa, Takaaki Fujii, Hitoshi Ojima, Junichi Nakamura, Takashi Yao, Ken Shirabe, Hiroyuki Kuwano

Pages: 4712-4718 Published online on: 05 September 2019
Open Access

LncRNA‑AWPPH activates TGF‑β1 in colorectal adenocarcinoma

Chengcong Liu, Bo Han, Jianjun Xin, Cheng Yang

Pages: 4719-4725 Published online on: 04 September 2019
Open Access

Long non‑coding RNA small nucleolar RNA host gene 7 is upregulated and promotes cell proliferation in thyroid cancer

Li Chen, Jing Zhu, Ling‑Jie Zhang

Pages: 4726-4734 Published online on: 27 August 2019
Open Access

Artesunate and sorafenib: Combinatorial inhibition of liver cancer cell growth

Hao Li, Kanghe Xu, Guangzhe Pian, Shu Sun

Pages: 4735-4743 Published online on: 05 September 2019
Open Access

Prognostic value of insulin‑like growth factor 2 mRNA‑binding protein 3 and vascular endothelial growth factor‑A in patients with primary non‑small‑cell lung cancer

Jiannan Liu, Ying Liu, Wenjing Gong, Xiangshuo Kong, Congcong Wang, Shuhua Wang, Aina Liu

Pages: 4744-4752 Published online on: 10 September 2019
Open Access

Identification and performance evaluation of housekeeping genes for microRNA expression normalization by reverse transcription‑quantitative PCR using liquid‑based cervical cytology samples

Rhafaela Lima Causin, Danielle Pessôa‑Pereira, Karen Cristina Borba Souza, Adriane Feijó Evangelista, Rui Manuel Vieira Reis, José Humberto Tavares Guerreiro Fregnani, Márcia Maria Chiquitelli Marques

Pages: 4753-4761 Published online on: 06 September 2019
Open Access

Comprehensive analysis of genomic alterations detected by next‑generation sequencing‑based tissue and circulating tumor DNA assays in Chinese patients with non‑small cell lung cancer

Hua Yang, Junjie Zhang, Lemeng Zhang, Xiaoping Wen, Yongzhong Luo, Dingquan Yao, Tianli Cheng, Huanqing Cheng, Huina Wang, Feng Lou, Jing Guo, Xiayuan Liang, Shanbo Cao, Jianhua Chen

Pages: 4762-4770 Published online on: 03 September 2019
Open Access

Downregulation of FOXP3 in neutrophils by IL‑8 promotes the progression of oral squamous cell carcinoma

Chuangui Zeng, Hai Kuang, Wan Fan, Xueru Chen, Tao Yu, Qinchao Tang, Zhuoqian Zhou, Feixin Liang

Pages: 4771-4777 Published online on: 09 September 2019
Open Access

Identification of cancer/testis antigen 2 gene as a potential hepatocellular carcinoma therapeutic target by hub gene screening with topological analysis

Jinwei Liu, Zhaojin Yu, Mingli Sun, Qianqian Liu, Minjie Wei, Hua Gao

Pages: 4778-4788 Published online on: 05 September 2019
Open Access

Expression of CREPT is associated with poor prognosis of patients with renal cell carcinoma

Huaqi Yin, Qingfei Cao, Haiyue Zhao, Shenheng Wang, Weinan Chen, Xiaowei Zhang, Zhijie Chang, Tao Xu, Xiongjun Ye

Pages: 4789-4797 Published online on: 09 September 2019
Open Access

Cancer‑related long noncoding RNAs show aberrant expression profiles and competing endogenous RNA potential in esophageal adenocarcinoma

Yang Yu, Xingxing Chen, Shundong Cang

Pages: 4798-4808 Published online on: 05 September 2019
Open Access

Knockdown of neuron‑specific enolase suppresses the proliferation and migration of NCI‑H209 cells

Xia Liu, Shousheng Liu, Juan Fu, Jinsheng Huang, Chengyin Weng, Xisheng Fang, Mingmei Guan, Yong Wu, Lin Yang, Guolong Liu

Pages: 4809-4815 Published online on: 04 September 2019
Open Access

Identification and meta‑analysis of copy number variation‑driven circadian clock genes for colorectal cancer

Wenliang Yuan, Li Liu, Cai Wei, Xiaobo Li, Dan Sun, Chaoxu Dai, Sicong Li, Sihua Peng, Linhua Jiang

Pages: 4816-4824 Published online on: 09 September 2019
Open Access

Primary impact of Gli1 on radioresistance in esophageal cancer

Fei Yao, Jinjing Yu, Yulin He, Jiaqi Liu, Huan Li, Qun Liu, Hui Long, Qingming Wu

Pages: 4825-4833 Published online on: 10 September 2019
Open Access

Characteristics of fecal gut microbiota in patients with colorectal cancer at different stages and different sites

Qinsong Sheng, Haixia Du, Xiaofei Cheng, Xiaobin Cheng, Yunning Tang, Lelin Pan, Qunmin Wang, Jianjiang Lin

Pages: 4834-4844 Published online on: 10 September 2019
Open Access

Prognostic values of transketolase family genes in ovarian cancer

Menghuang Zhao, Miaomiao Ye, Junhan Zhou, Xueqiong Zhu

Pages: 4845-4857 Published online on: 06 September 2019
Open Access

Anticancer effect of XAV939 is observed by inhibiting lactose dehydrogenase A in a 3‑dimensional culture of colorectal cancer cells

Dahee Kim, Byumseok Koh, Kwang Rok Kim, Ki Young Kim, Won Hoon Jung, Hi Youn Kim, Sungsub Kim, Sang Dal Rhee

Pages: 4858-4864 Published online on: 05 September 2019
Open Access

Surgery in patients with small cell lung cancer: A period propensity score matching analysis of the Seer database, 2010‑2015

Xiaojun Du, Dan Tian, Langbo Liu, Zhongben Tang, Jiarong Xiao, Wen Liu, Shizhang Yuan, Xi Cao, Haiyu Zhou, Jian Zhang

Pages: 4865-4881 Published online on: 03 September 2019
Open Access

Diagnostic and prognostic value of microRNA‑193b in patients with glioma and its effect on tumor progression

Mingtao Zhu, Wei Zhao, Hui Zhao, Jing Zhang

Pages: 4882-4890 Published online on: 06 September 2019
Open Access

Prognostic value and association of Lauren classification with VEGF and VEGFR‑2 expression in gastric cancer

Xiayi Li, Xueru Zhu, Yiwei Wang, Ruifen Wang, Lifeng Wang, Mei‑Ling Zhu, Leizhen Zheng

Pages: 4891-4899 Published online on: 06 September 2019
Open Access

High expression of AGBL2 is a novel prognostic factor of adverse outcome in patients with ovarian carcinoma

Wei‑Peng He, Li‑Li Wang

Pages: 4900-4906 Published online on: 09 September 2019
Open Access

A three-gene novel predictor for improving the prognosis of cervical cancer

Ting-Ting Ding, Hu Ma, Ji-Hong Feng

Pages: 4907-4915 Published online on: 05 September 2019
Open Access

Effects of radioactive 125I on apoptosis of HGC-27 gastric cancer cells

Yong Yang, Aifei Chen, Jun Ma, Aiping Wu, Fazhen Xu

Pages: 4916-4922 Published online on: 09 September 2019

Impact of spheroid culture on molecular and functional characteristics of bladder cancer cell lines

Takahiro Yoshida, Nikolai A. Sopko, Max Kates, Xiaopu Liu, Gregory Joice, David J. Mcconkey, Trinity J. Bivalacqua

Pages: 4923-4929 Published online on: 29 August 2019

MicroRNA‑31 is a potential biomarker for screening B‑lymphoblastic leukemia in children

Yan Zhang, Xin Li, Liping Bai, Li Li, Danhong Li, Xue Ding, Bo Wang, Chengwei Li

Pages: 4930-4935 Published online on: 10 September 2019

HDGF and PRKCA upregulation is associated with a poor prognosis in patients with lung adenocarcinoma

Honghong Jiang, Qiaofen Fu, Xin Song, Chunlei Ge, Ruilei Li, Zhen Li, Baozhen Zeng, Chunyan Li, Ying Wang, Yuanbo Xue, Rongcheng Luo, Weiyi Fang

Pages: 4936-4946 Published online on: 05 September 2019
Open Access

Prospective comparison of the value of CRASH and CARG toxicity scores in predicting chemotherapy toxicity in geriatric oncology

Jun Zhang, Xin Liao, Jin Feng, Tiejun Yin, Yajun Liang

Pages: 4947-4955 Published online on: 10 September 2019

Multi‑pathway integrated adjustment mechanism of licorice flavonoids presenting anti‑inflammatory activity

Xiaomeng Yu, Yongrui Bao, Xiansheng Meng, Shuai Wang, Tianjiao Li, Xin Chang, Weifeng Xu, Guanlin Yang, Tao Bo

Pages: 4956-4963 Published online on: 04 September 2019

AGR2 silencing contributes to metformin‑dependent sensitization of colorectal cancer cells to chemotherapy

Andrea Martisova, Lucia Sommerova, Katarina Kuricova, Jan Podhorec, Borivoj Vojtesek, Katerina Kankova, Roman Hrstka

Pages: 4964-4973 Published online on: 04 September 2019

Plasma desacyl ghrelin‑to‑acyl ghrelin ratio is a predictor of postoperative complications and prognosis after pancreaticoduodenectomy

Takahiro Nishida, Hironobu Tsubouchi, Takeomi Hamada, Naoya Imamura, Masahide Hiyoshi, Koichi Yano, Kenji Kangawa, Masamitsu Nakazato, Atsushi Nanashima

Pages: 4974-4983 Published online on: 06 September 2019

Antiviral therapy may decrease HBx, affecting cccDNA and MSL2 in hepatocarcinogenesis

Xue‑Li Jin, Suk Kyun Hong, Hwajung Kim, Sun‑Kyung Lee, Nam‑Joon Yi, Kwang‑Woong Lee, Kyung‑Suk Suh

Pages: 4984-4991 Published online on: 10 September 2019

BNP as a marker for early prediction of anthracycline‑induced cardiotoxicity in patients with breast cancer

Xiang Lu, Yingying Zhao, Caiping Chen, Chao Han, Li Xue, Dan Xing, Ou Huang, Min Tao

Pages: 4992-5001 Published online on: 09 September 2019
Open Access

Combination of checkpoint inhibitors with radiotherapy in esophageal squamous cell carcinoma treatment: A novel strategy (Review)

Xiu‑Yong Liao, Chao‑Yuan Liu, Jian‑Feng He, Li‑Shu Wang, Tao Zhang

Pages: 5011-5021 Published online on: 19 September 2019
Open Access

Cancer stem cells in esophageal squamous cell cancer (Review)

Qian Wu, Zhe Wu, Cuiyu Bao, Wenjing Li, Hui He, Yanling Sun, Zimin Chen, Hao Zhang, Zhifeng Ning

Pages: 5022-5032 Published online on: 20 September 2019
Open Access

Multiple roles of microRNA‑146a in immune responses and hepatocellular carcinoma (Review)

Huihui Wang, Xuemei Li, Tao Li, Lianzi Wang, Xian Wu, Jiaqing Liu, Yuanhong Xu, Wei Wei

Pages: 5033-5042 Published online on: 12 September 2019
Open Access

Four targeted genes for predicting the prognosis of colorectal cancer: A bioinformatics analysis case

Qinglai Bian, Jiaxu Chen, Wenqi Qiu, Chenxi Peng, Meifang Song, Xuebin Sun, Yueyun Liu, Fengmin Ding, Jianbei Chen, Liqing Zhang

Pages: 5043-5054 Published online on: 13 September 2019
Open Access

Inhibition of long non‑coding RNA‑AWPPH decreases osteosarcoma cell proliferation, migration and invasion

Wenbin Ding, Dajiang Wu, Fang Ji, Hao Zhang

Pages: 5055-5062 Published online on: 20 September 2019
Open Access

Next generation DNA sequencing of atypical choroid plexus papilloma of brain: Identification of novel mutations in a female patient by Ion Proton

Mohiuddin M. Taher, Amal Ali Hassan, Muhammad Saeed, Raid A. Jastania, Tahani H. Nageeti, Hisham Alkhalidi, Ghida Dairi, Zainularifeen Abduljaleel, Mohammad Athar, Abdellatif Bouazzaoui, Wafa M. El‑Bjeirami, Faisal A. Al‑Allaf

Pages: 5063-5076 Published online on: 19 September 2019
Open Access

Genetic alterations in 47 patients with a novel myelodysplastic syndrome diagnosis at a single center

Pan Zhao, Jiayue Qin, Weiyi Liu, Richeng Quan, Haiyan Xiao, Chi Liu, Liu Li, Yan Lv, Qianze Zhu, Hongzhi Wang, Xiaoqing Guo, Juan Wang, Xiaomei Hu

Pages: 5077-5084 Published online on: 12 September 2019
Open Access

Different responses to anti‑programmed cell death protein 1 (PD‑1) immunotherapy in a patient with Lynch syndrome and metachronous urothelial and colon cancer: A case report

Yu Feng, Yufeng Cao, Mingming Yuan, Rongrong Chen, Xue Ji, Xingsheng Hu

Pages: 5085-5090 Published online on: 23 September 2019
Open Access

Clinical outcomes in primary scalp angiosarcoma

Yong Zhang, Yanwen Yan, Ming Zhu, Cheng Chen, Nanhang Lu, Fazhi Qi, Jiaqi Liu

Pages: 5091-5096 Published online on: 19 September 2019
Open Access

The response of phyllodes tumor of the breast to anticancer therapy: An in vitro and ex vivo study

Alicja Urbaniak, Fariba Jousheghany, Youzhong Yuan, Sergio Piña‑Oviedo, Adam Huczyński, Magdalena Delgado, Thomas Kieber‑Emmons, Behjatolah Monzavi‑Karbassi, Timothy C. Chambers

Pages: 5097-5106 Published online on: 06 September 2019
Open Access

Upregulation of SPDEF is associated with poor prognosis in prostate cancer

Jan Meiners, Katharina Schulz, Katharina Möller, Doris Höflmayer, Christoph Burdelski, Claudia Hube‑Magg, Ronald Simon, Cosima Göbel, Andrea Hinsch, Viktor Reiswich, Sören Weidemann, Jacob R. Izbicki, Guido Sauter, Frank Jacobsen, Christina Möller‑Koop, Tim Mandelkow, Niclas C. Blessin, Florian Lutz, Florian Viehweger, Maximillian Lennartz, Christoph Fraune, Hans Heinzer, Sarah Minner, Sarah Bonk, Hartwig Huland, Markus Graefen, Thorsten Schlomm, Franziska Büscheck

Pages: 5107-5118 Published online on: 19 September 2019
Open Access

Exosome complex genes mediate RNA degradation and predict survival in mantle cell lymphoma

Weilong Zhang, Junyong Zhu, Xue He, Xiaoni Liu, Jinhang Li, Wei Li, Ping Yang, Jing Wang, Kai Hu, Xiuru Zhang, Xiru Li, Hongmei Jing

Pages: 5119-5128 Published online on: 11 September 2019
Open Access

Prognostic and metastasis‑related factors in colorectal neuroendocrine tumors: A cross‑sectional study based on the Surveillance, Epidemiology and End Results

Jinmao Zou, Shangxiang Chen, Guoda Lian, Ruomeng Li, Yaqing Li, Kaihong Huang, Yinting Chen

Pages: 5129-5138 Published online on: 18 September 2019
Open Access

Advantages of digital PCR in the detection of low abundance BCR‑ABL1 gene in patients with chronic myeloid leukemia

Zhiling Yan, Qian Sun, Huanxin Zhang, Yahui Han, Jianlin Qiao, Mingshan Niu, Shengyun Zhu, Kai Zhao, Qingyun Wu, Hai Cheng, Jiang Cao, Lingyu Zeng, Zhenyu Li, Kailin Xu

Pages: 5139-5144 Published online on: 12 September 2019
Open Access

Mechanism of miR‑107‑targeting of regulator of G‑protein signaling 4 in hepatocellular carcinoma

Di Xiao, Hai‑Xia Gao

Pages: 5145-5154 Published online on: 12 September 2019
Open Access

In vitro measurement of glucose uptake after radiation and cetuximab treatment in head and neck cancer cell lines using 18F‑FDG, gamma spectrometry and PET/CT

Natasa Matic, Marcus Ressner, Emilia Wiechec, Karin Roberg

Pages: 5155-5162 Published online on: 24 September 2019
Open Access

Evaluation of the target genes of arsenic trioxide in pancreatic cancer by bioinformatics analysis

Cong‑Ya Zhou, Liu‑Yun Gong, Rong Liao, Ning‑Na Weng, Yao‑Yue Feng, Yi‑Ping Dong, Hong Zhu, Ya‑Qin Zhao, Yuan‑Yuan Zhang, Qing Zhu, Su‑Xia Han

Pages: 5163-5172 Published online on: 19 September 2019
Open Access

Downregulation of ABCA1 and ABCG1 transporters by simvastatin in cholangiocarcinoma cells

Pattaya Seeree, Tavan Janvilisri, Thaned Kangsamaksin, Rutaiwan Tohtong, Supeecha Kumkate

Pages: 5173-5184 Published online on: 17 September 2019
Open Access

Screening and identification of key biomarkers in lung squamous cell carcinoma by bioinformatics analysis

Jun Man, Xiaomei Zhang, Huan Dong, Simin Li, Xiaolin Yu, Lihong Meng, Xiaofeng Gu, Hong Yan, Jinwei Cui, Yuxin Lai

Pages: 5185-5196 Published online on: 16 September 2019
Open Access

Exosomal long non‑coding RNA DLX6‑AS1 as a potential diagnostic biomarker for non‑small cell lung cancer

Xilin Zhang, Huihui Guo, Ying Bao, Huanming Yu, Dong Xie, Xiang Wang

Pages: 5197-5204 Published online on: 19 September 2019
Open Access

Evaluating and validating the predictive ability of preoperative systemic inflammatory/immune cells in gastric cancer following R0 resection

Wenbo Xue, Xuezhong Xu, Yulin Tan, Yan Qian, Hao Wang, Yibo Wang, Yixin Xu, Xiaojun Zhu, Peng Jiang, Wei Ding

Pages: 5205-5214 Published online on: 13 September 2019
Open Access

High interleukin‑8 and/or extracellular signal‑regulated kinase 2 expression predicts poor prognosis in patients with hepatocellular carcinoma

Youyuan Deng, Zhijie Ning, Zhiya Hu, Qianle Yu, Bin He, Guohuang Hu

Pages: 5215-5224 Published online on: 23 September 2019
Open Access

Profiles of tumor‑infiltrating immune cells in renal cell carcinoma and their clinical implications

Gongmin Zhu, Lijiao Pei, Hubin Yin, Fan Lin, Xinyuan Li, Xin Zhu, Weiyang He, Xin Gou

Pages: 5235-5242 Published online on: 20 September 2019
Open Access

Identification of prognostic biomarkers for malignant melanoma using microarray datasets

Guanyu Lin, Guoqian Yin, Yuyong Yan, Bojie Lin

Pages: 5243-5254 Published online on: 24 September 2019
Open Access

Selective downregulation of distinct circRNAs in the tissues and plasma of patients with primary hepatic carcinoma

Yan Ding, Anning Fang, Jialai Yan, Jie Duan, Nianyue Wang, Yongxiang Yi, Chuanlai Shen

Pages: 5255-5268 Published online on: 23 September 2019
Open Access

A novel technique for removing large gastric subepithelial tumors with ESD method in the subcardia region

Bingtuan Liu, Han Chen, Weifeng Zhang, Guoxin Zhang

Pages: 5277-5282 Published online on: 19 September 2019
Open Access

Investigation of miRNA‑ and lncRNA‑mediated competing endogenous RNA network in cholangiocarcinoma

Yanxin He, Chao Liu, Pan Song, Zhigang Pang, Zhuomao Mo, Chuiguo Huang, Tingting Yan, Meng Sun, Xianen Fa

Pages: 5283-5293 Published online on: 12 September 2019
Open Access

TIM‑3 expression and its association with overall survival in primary osteosarcoma

Feifei Pu, Fengxia Chen, Zhicai Zhang, Xiangcheng Qing, Hui Lin, Lei Zhao, Ping Xia, Zengwu Shao

Pages: 5294-5300 Published online on: 12 September 2019
Open Access

Prognostic value of nuclear FBI‑1 in patients with rectal cancer with or without preoperative radiotherapy

Chao‑Jie Wang, Chu‑Rui Chao, Hui‑Min Liu, Yan‑Yan Zhu, Gunnar Adell, Ingvar Jarlsfelt, Hong Zhang, Xiao‑Feng Sun

Pages: 5301-5309 Published online on: 19 September 2019
Open Access

A predicted risk score based on the expression of 16 autophagy‑related genes for multiple myeloma survival

Fang‑Xiao Zhu, Xiao‑Tao Wang, Hui‑Qiong Zeng, Zhi‑Hua Yin, Zhi‑Zhong Ye

Pages: 5310-5324 Published online on: 19 September 2019
Open Access

Effects of cisatracurium on epithelial‑to‑mesenchymal transition in esophageal squamous cell carcinoma

Wenyan Lv, Jingyu Wang, Shubao Zhang

Pages: 5325-5331 Published online on: 12 September 2019
Open Access

SNX3 suppresses the migration and invasion of colorectal cancer cells by reversing epithelial‑to‑mesenchymal transition via the β‑catenin pathway

Biran Pan, Tongtong Zhang, Wei Yang, Yanjun Liu, Yuning Chen, Zheng Zhou, Yan Tang, Jiawei Zeng, Yilun Liu, Cong Zhao, Yuanbiao Guo

Pages: 5332-5340 Published online on: 12 September 2019
Open Access

Overexpression of PSMA7 predicts poor prognosis in patients with gastric cancer

Shujing Xia, Qi Tang, Xudong Wang, Lili Zhang, Lizhou Jia, Duo Wu, Pingxiang Xu, Xiumei Zhang, Genxiong Tang, Tingting Yang, Zhenqing Feng, Lungen Lu

Pages: 5341-5349 Published online on: 19 September 2019
Open Access

Identification of RAD54 homolog B as a promising therapeutic target for breast cancer

Jing Feng, Juanjuan Hu, Ying Xia

Pages: 5350-5362 Published online on: 12 September 2019
Open Access

Changing expression profiles of lncRNAs, circRNAs and mRNAs in esophageal squamous carcinoma

Jia Song, Yanrong Lu, Wei Sun, Mei Han, Yuan Zhang, Jinrong Zhang

Pages: 5363-5373 Published online on: 19 September 2019
Open Access

Upregulation of sphingosine kinase 1 is associated with recurrence and poor prognosis in papillary thyroid carcinoma

Jie Li, Bo Zhang, Yang Bai, Yonghong Liu, Buyong Zhang, Jian Jin

Pages: 5374-5382 Published online on: 24 September 2019
Open Access

Radiofrequency radiation from nearby mobile phone base stations‑a case comparison of one low and one high exposure apartment

Tarmo Koppel, Mikko Ahonen, Michael Carlberg, Lena K. Hedendahl, Lennart Hardell

Pages: 5383-5391 Published online on: 20 September 2019
Open Access

LINC01638 lncRNA mediates the postoperative distant recurrence of bladder cancer by upregulating ROCK2

Shouxian Yuan, Xiuhua Luan, Guiqiang Han, Kecun Guo, Shenghui Wang, Xiangkai Zhang

Pages: 5392-5398 Published online on: 26 September 2019
Open Access

PD‑L1 expression levels on tumor cells affect their immunosuppressive activity

Yang Zheng, You‑Chen Fang, Jing Li

Pages: 5399-5407 Published online on: 20 September 2019
Open Access

Talin1 knockdown prohibits the proliferation and migration of colorectal cancer cells via the EMT signaling pathway

Ling Ji, Feizhao Jiang, Xianping Cui, Chengkun Qin

Pages: 5408-5416 Published online on: 20 September 2019
Open Access

Distinct expression and prognostic value of OTU domain‑containing proteins in non‑small‑cell lung cancer

Jingjing Deng, Gouxin Hou, Zhixian Fang, Jialiang Liu, Xiao‑Dong Lv

Pages: 5417-5427 Published online on: 19 September 2019
Open Access

Polyphyllin I and VII potentiate the chemosensitivity of A549/DDP cells to cisplatin by enhancing apoptosis, reversing EMT and suppressing the CIP2A/AKT/mTOR signaling axis

Feifei Feng, Peng Cheng, Chaochao Wang, Yongbin Wang, Wei Wang

Pages: 5428-5436 Published online on: 20 September 2019
Open Access

Retrospective study on the efficacy of bisphosphonates in tyrosine kinase inhibitor‑treated patients with non‑small cell lung cancer exhibiting bone metastasis

Xiaoxian Cui, Shaoli Li, Jincui Gu, Ziying Lin, Bipeng Lai, Lixia Huang, Jinlun Feng, Baomo Liu, Yanbin Zhou

Pages: 5437-5447 Published online on: 16 September 2019
Open Access

The added value of intravoxel incoherent motion diffusion weighted imaging parameters in differentiating high‑grade pancreatic neuroendocrine neoplasms from pancreatic ductal adenocarcinoma

Wanling Ma, Mengqi Wei, Zhiwei Han, Yongqiang Tang, Qi Pan, Guangwen Zhang, Jing Ren, Yi Huan, Na Li

Pages: 5448-5458 Published online on: 13 September 2019
Open Access

Identification of candidate genes for the diagnosis and treatment of cholangiocarcinoma using a bioinformatics approach

Mi Zhou, Yabin Zhu, Ruixia Hou, Xianbo Mou, Jun Tan

Pages: 5459-5467 Published online on: 20 September 2019
Open Access

POPDC3 is a potential biomarker for prognosis and radioresistance in patients with head and neck squamous cell carcinoma

Xu He, Hongfa Xu, Wei Zhao, Meixiao Zhan, Yong Li, Hongyi Liu, Li Tan, Ligong Lu

Pages: 5468-5480 Published online on: 19 September 2019
Open Access

A‑1210477, a selective MCL‑1 inhibitor, overcomes ABT‑737 resistance in AML

Qing Wang, Siguo Hao

Pages: 5481-5489 Published online on: 19 September 2019
Open Access

Propyl isothiocyanate induces apoptosis in gastric cancer cells by oxidative stress via glutathione depletion

Ling Huang, Chen Cai, Wei Dang, Jian‑Hua Lu, Gang‑Feng Hu, Jun Gu

Pages: 5490-5498 Published online on: 18 September 2019
Open Access

Identification of biomarkers associated with histological grade and prognosis of gastric cancer by co‑expression network analysis

Wenjing Chen, Weiteng Zhang, Ruisen Wu, Yiqi Cai, Xiangyang Xue, Jun Cheng

Pages: 5499-5507 Published online on: 13 September 2019
Open Access

Diagnostic and prognostic value of the BEX family in lung adenocarcinoma

Zhong‑Hao Zhang, Zhi‑Yu Luan, Fei Han, Hong‑Qiang Chen, Wen‑Bin Liu, Jin‑Yi Liu, Jia Cao

Pages: 5523-5533 Published online on: 20 September 2019

Chemovirotherapy for pancreatic cancer: Gemcitabine plus oncolytic measles vaccine virus

Verena May, Susanne Berchtold, Alexander Berger, Sascha Venturelli, Markus Burkard, Christian Leischner, Nisar P. Malek, Ulrich M. Lauer

Pages: 5534-5542 Published online on: 20 September 2019

MicroRNA‑34a inhibits bladder cancer cell migration and invasion, and upregulates PTEN expression

Zhen-Shan Ding, Yu-Hui He, Yi-Sen Deng, Pan-Xin Peng, Jian-Feng Wang, Xing Chen, Pei-Yu Zhao, Xiao-Feng Zhou

Pages: 5549-5554 Published online on: 18 September 2019

Evaluation of the impact of linked color imaging for improving the visibility of colonic polyp

Yasuyoshi Tanaka, Takuya Inoue, Kazuki Kakimoto, Kei Nakazawa, Hideki Tawa, Yuki Hirata, Toshihiko Okada, Sadaharu Nouda, Ken Kawakami, Toshihisa Takeuchi, Yutaro Egashira, Kazuhide Higuchi

Pages: 5555-5560 Published online on: 24 September 2019

Nasal NK/T cell lymphoma mimicking mucosa‑associated lymphoid tissue lymphoma in morphology: A case report

Guohua Yu, Xiaoqian Liu, Huihui Zhou, Licai An, Hongyan Li, Shishou Wu, Yinghui Liu, Xubo Pan, Guimei Qu, Xiaoxia Chu

Pages: 5561-5566 Published online on: 13 September 2019
Open Access

Ubiquitin‑specific peptidase 22 promotes proliferation and metastasis in human colon cancer

Xiao Yuan, Hao Wang, Aman Xu, Xingyang Zhu, Yanqing Zhan, Wenbin Wang

Pages: 5567-5576 Published online on: 16 September 2019

GEFT protein expression in digestive tract malignant tumors and its clinical significance

Yuanyuan Wang, Bing Zhang, Ge Gao, Yinping Zhang, Qingxin Xia

Pages: 5577-5590 Published online on: 24 September 2019

High expression of the transcriptional coactivator TAZ is associated with a worse prognosis and affects cell proliferation in patients with medulloblastoma

Hao Wang, Ji Zhou, Dong Yang, Liang Yi, Xuhui Wang, Yangqing Ou, Donghong Yang, Lunshan Xu, Minhui Xu

Pages: 5591-5599 Published online on: 11 September 2019

Upregulation of DLC‑1 inhibits pancreatic cancer progression: Studies with clinical samples and a pancreatic cancer model

Bo Chen, Mingzheng Xu, Ming Xu

Pages: 5600-5606 Published online on: 16 September 2019

The combined use of EphA2/MMP‑2 expression and MRI findings contributes to the determination of cerebral glioma grade

Fangfang Suo, Binfeng Zhong, Fangfang Lu, Zhihui Dong

Pages: 5607-5613 Published online on: 24 September 2019

Clinical significance of invasion distance relative to prognosis in pathological T3 colorectal cancer

Masatoshi Nomura, Hidekazu Takahashi, Makoto Fujii, Norikatsu Miyoshi, Naotsugu Haraguchi, Taishi Hata, Chu Matsuda, Hirofumi Yamamoto, Tsunekazu Mizushima, Masaki Mori, Yuichiro Doki

Pages: 5614-5620 Published online on: 24 September 2019

Identification and validation of microRNAs and their targets expressed in osteosarcoma

Can Zhang, Jun Wan, Feng Long, Qing Liu, Hongbo He

Pages: 5628-5636 Published online on: 13 September 2019

Frequency of hematologic malignancies in the population of Arica, Chile

Gloria Baeza Pérez, Gloria M. Calaf, María Teresa Montalvo Villalba, Katherine Salgado Prieto, Fresia Caba Burgos

Pages: 5637-5643 Published online on: 12 September 2019
Open Access

Multicomponent nutritional supplement Oncoxin and its influence on quality of life and therapy toxicity in patients receiving adjuvant chemotherapy

Dilyara Radikovna Kaidarova, Mikhail Valeryevich Kopp, Vadim S. Pokrovsky, Мaia Dzhugashvili, Zhanna Mukhataevna Akimzhanova, Ramil Zufarovich Abdrakhmanov, Elena Nikolaevna Babich, Evgeniy Viktorovich Bilan, Anton Valeryevich Byakhov, Sergey Nikolaevich Gurov, Irina Albertovna Koroleva, Anastasiia Sergeevna Mochalova, Svetlana Sergeevna Povaga, Maxim Vladimirovich Raigorodsky, Arthur Sidorovich Saifullin, Eduardo Sanz, Fedor Igorevich Petrovskiy

Pages: 5644-5652 Published online on: 13 September 2019
Open Access

[Corrigendum] Isolation of circulating tumor cells in patients undergoing surgery for esophageal cancer and a specific confirmation method

Yunpeng Zhao, Shukang Zhao, Yingjie Chen, Xiaopeng Dong, Chuanliang Peng, Qifeng Sun, Lei Shan, Zhendan Wang, Xiaogang Zhao

Pages: 5653-5653 Published online on: 18 September 2019
Open Access

[Corrigendum] Polydatin inhibits hepatocellular carcinoma via the AKT/STAT3‑FOXO1 signaling pathway

Jian Jiang, Yaodong Chen, Tianxiu Dong, Minlu Yue, Yu Zhang, Tingting An, Jiuwei Zhang, Pengfei Liu, Xiuhua Yang

Pages: 5654-5654 Published online on: 12 September 2019
Journal Cover

November 2019
Volume 18 Issue 5

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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