Journal Articles

Open Access

Molecular basis of degenerative spinal disorders from a proteomic perspective (Review)

Chang Liu, Minghui Yang, Libangxi Liu, Yang Zhang, Qi Zhu, Cong Huang, Hongwei Wang, Yaqing Zhang, Haiyin Li, Changqing Li, Bo Huang, Chencheng Feng, Yue Zhou

Pages: 9-19 Published online on: 12 November 2019
Open Access

Aspirin metabolites 2,3‑DHBA and 2,5‑DHBA inhibit cancer cell growth: Implications in colorectal cancer prevention

Ranjini Sankaranarayanan, Chaitanya K. Valiveti, Rakesh Dachineni, D. Ramesh Kumar, Tana Lick, G. Jayarama Bhat

Pages: 20-34 Published online on: 18 November 2019
Open Access

MicroRNA‑542‑3p represses OTUB1 expression to inhibit migration and invasion of esophageal cancer cells

Jun Sun, Yong Deng, Jin Shi, Wengang Yang

Pages: 35-42 Published online on: 20 November 2019
Open Access

miR‑204 inhibits the osteogenic differentiation of mesenchymal stem cells by targeting bone morphogenetic protein 2

Xiaofeng Jiang, Zuofu Zhang, Tao Peng, Guangda Wang, Qiang Xu, Guangrun Li

Pages: 43-50 Published online on: 05 November 2019
Open Access

Exploratory study on application of MALDI‑TOF‑MS to detect serum and urine peptides related to small cell lung carcinoma

Panpan Lv, Zeyuan Liu, Bin Xu, Chuanhao Tang, Xiaoyan Li, Haifeng Qin, Shaoxing Yang, Hongjun Gao, Kun He, Xiaoqing Liu

Pages: 51-60 Published online on: 05 November 2019
Open Access

KR‑12‑a6 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells via BMP/SMAD signaling

Lanqing Fu, Peicheng Jin, Yajun Hu, Hougen Lu, Linlin Su

Pages: 61-68 Published online on: 22 November 2019
Open Access

Silencing of RBP‑JK promotes the differentiation of bone marrow mesenchymal stem cells into vascular endothelial cells

Zhengliang Luo, Yong Dai, Min Chen, Chen Zhu, Kerong Wu, Guoyuan Li, Xifu Shang

Pages: 69-76 Published online on: 06 November 2019
Open Access

Anti‑Nogo‑A antibody promotes brain function recovery after cardiopulmonary resuscitation in rats by reducing apoptosis

Qinqin Wu, Haihong Zhang, Hu Nie, Zhi Zeng

Pages: 77-88 Published online on: 20 November 2019
Open Access

The inhibition of miR‑101a‑3p alleviates H/R injury in H9C2 cells by regulating the JAK2/STAT3 pathway

Jingying Liu, Juanjuan Wang, Yuzhen Ning, Fengying Chen

Pages: 89-96 Published online on: 05 November 2019
Open Access

Disorders of sex development: Genetic characterization of a patient cohort

Mary García-Acero, Olga Moreno-Niño, Fernando Suárez-Obando, Mónica Molina, María Carolina Manotas, Juan Carlos Prieto, Catalina Forero, Camila Céspedes, Jaime Pérez, Nicolas Fernandez, Adriana Rojas

Pages: 97-106 Published online on: 12 November 2019
Open Access

Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia

Joon Ha Park, Ji Hyeon Ahn, Dae Won Kim, Tae‑Kyeong Lee, Cheol Woo Park, Young Eun Park, Jae‑Chul Lee, Hyang‑Ah Lee, Go Eun Yang, Moo‑Ho Won, Choong‑Hyun Lee

Pages: 107-114 Published online on: 20 November 2019
Open Access

Neuroprotective effect of CPCGI on Alzheimer's disease and its mechanism

Xiaopeng Wang, Jing Zhao

Pages: 115-122 Published online on: 20 November 2019
Open Access

Sevoflurane attenuates brain damage through inhibiting autophagy and apoptosis in cerebral ischemia‑reperfusion rats

Cun‑Xian Shi, Jin Jin, Xue‑Qin Wang, Teng Song, Guang‑Hong Li, Ke‑Zhong Li, Jia‑Hai Ma

Pages: 123-130 Published online on: 20 November 2019
Open Access

Iridoid glycosides from Radix Scrophulariae attenuates focal cerebral ischemia‑reperfusion injury via inhibiting endoplasmic reticulum stress‑mediated neuronal apoptosis in rats

Yanyue Chen, Lei Zhang, Xueyuan Gong, Hengpei Gong, Rubin Cheng, Fengmei Qiu, Xiaoming Zhong, Zhen Huang

Pages: 131-140 Published online on: 20 November 2019
Open Access

Construction and analysis of circular RNA molecular regulatory networks in clear cell renal cell carcinoma

Chuanyu Ma, Jie Qin, Junpeng Zhang, Xingli Wang, Dongjun Wu, Xiunan Li

Pages: 141-150 Published online on: 11 November 2019
Open Access

Interleukin‑37 is increased in peripheral blood mononuclear cells of coronary heart disease patients and inhibits the inflammatory reaction

Huimin Li, Chen Shen, Bingni Chen, Jing Du, Bin Peng, Wei Wang, Fanwu Chi, Xiaoqiang Dong, Zhong Huang, Chao Yang

Pages: 151-160 Published online on: 06 November 2019
Open Access

Roxatidine inhibits fibrosis by inhibiting NF‑κB and MAPK signaling in macrophages sensing breast implant surface materials

Litong Ji, Tie Wang, Lining Tian, Hongjiang Song, Meizhuo Gao

Pages: 161-172 Published online on: 12 November 2019
Open Access

Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells

Sheng Zhou, Jing Yang, Mingwei Wang, Danying Zheng, Yizhi Liu

Pages: 173-180 Published online on: 12 November 2019
Open Access

The COL6A1 rs201153092 single nucleotide polymorphism, associates with thoracic ossification of the posterior longitudinal ligament

Peng Wang, Ze Teng, Xiaoguang Liu, Xiao Liu, Chao Kong, Shibao Lu

Pages: 191-200 Published online on: 22 November 2019
Open Access

Mitochondrial tRNAAla 5601C>T variant may affect the clinical expression of the LHON‑related ND4 11778G>A mutation in a family

Yu Ding, Yu‑Feng Ye, Mei‑Ya Li, Bo‑Hou Xia, Jian‑Hang Leng

Pages: 201-208 Published online on: 22 November 2019
Open Access

miR‑218 functions as a tumor suppressor gene in cervical cancer

Zhen Liu, Lin Mao, Linlin Wang, Hong Zhang, Xiaoxia Hu

Pages: 209-219 Published online on: 11 November 2019
Open Access

Rhizoma Paridis total saponins alleviate H2O2‑induced oxidative stress injury by upregulating the Nrf2 pathway

Baocheng Zhao, Zhenjun Wang, Jiagang Han, Guanghui Wei, Bingqiang Yi, Zhulin Li

Pages: 220-228 Published online on: 20 November 2019
Open Access

Extraction and isolation of the active ingredients of dandelion and its antifungal activity against Candida albicans

Yinku Liang, Hongbo Duan, Ping Zhang, Hao Han, Feixiong Gao, Yunxiang Li, Zhongyang Xu

Pages: 229-239 Published online on: 06 November 2019
Open Access

A novel GPR143 mutation in a Chinese family with X‑linked ocular albinism type 1

Xuhui Gao, Tiecheng Liu, Xuan Cheng, Aiai Dai, Wei Liu, Runpu Li, Maonian Zhang

Pages: 240-248 Published online on: 12 November 2019
Open Access

Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells

Yifan Wu, Yiyang Zhao, Xuanhong He, Zhiqiang He, Tian Wang, Linxi Wan, Lai Chen, Nianlong Yan

Pages: 249-257 Published online on: 06 November 2019
Open Access

Berberine ameliorates lipopolysaccharide‑induced inflammatory responses in mouse inner medullary collecting duct‑3 cells by downregulation of NF‑κB pathway

Dong‑Gu Kim, Ji‑Won Choi, Il‑Joo Jo, Myoung‑Jin Kim, Ho‑Sub Lee, Seung‑Heon Hong, Ho‑Joon Song, Gi‑Sang Bae, Sung‑Joo Park

Pages: 258-266 Published online on: 19 November 2019
Open Access

Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats

Yang Jiao, Yang Yu, Bo Li, Xiyan Gu, Keliang Xie, Guolin Wang, Yonghao Yu

Pages: 282-290 Published online on: 05 November 2019
Open Access

LncRNA MALAT1 promotes neuropathic pain progression through the miR‑154‑5p/AQP9 axis in CCI rat models

Jianping Wu, Chuanguang Wang, Haiyang Ding

Pages: 291-303 Published online on: 20 November 2019
Open Access

Dioscin attenuates oxLDL uptake and the inflammatory reaction of dendritic cells under high glucose conditions by blocking p38 MAPK

Ying Li, Yong Li, Te Yang, Ming Wang

Pages: 304-310 Published online on: 06 November 2019
Open Access

Screening and identification of key biomarkers in prostate cancer using bioinformatics

Song Li, Junqing Hou, Weibo Xu

Pages: 311-319 Published online on: 06 November 2019
Open Access

CARD10 promotes the progression of renal cell carcinoma by regulating the NF‑κB signaling pathway

Longfei Peng, Ke He, Zhangjun Cao, Liangkuan Bi, Dexin Yu, Qi Wang, Jinyou Wang

Pages: 329-337 Published online on: 21 November 2019
Open Access

Increased mitochondrial DNA copy number protects hair cells and HEI‑OC1 cells against drug‑induced apoptosis

Honglin Mei, Dongmei Mei, Huiqian Yu, Shan Sun, Yan Chen, Yanping Zhang, Renjie Chai, Huawei Li

Pages: 338-346 Published online on: 20 November 2019
Open Access

A 21‑gene Support Vector Machine classifier and a 10‑gene risk score system constructed for patients with gastric cancer

Hui Jiang, Jiming Gu, Jun Du, Xiaowei Qi, Chengjia Qian, Bojian Fei

Pages: 347-359 Published online on: 21 November 2019
Open Access

Overexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma

Jie Wei, Zhijie Xu, Xi Chen, Xiang Wang, Shuangshuang Zeng, Long Qian, Xue Yang, Chunlin Ou, Wei Lin, Zhicheng Gong, Yuanliang Yan

Pages: 360-370 Published online on: 20 November 2019

IL‑37 expression is decreased in patients with hyperhomocysteinemia and protects cells from inflammatory injury by homocysteine

Sen Wang, Zhen Huang, Wenrui Li, Suhui He, Hongmei Wu, Jiandong Zhu, Rumeng Li, Zhuangyan Liang, Zhangquan Chen

Pages: 371-378 Published online on: 06 November 2019

Retinal proteomic evaluation of rats following streptozotocin‑injection using shotgun proteomics

Hiroko Otake, Tetushi Yamamoto, Saori Deguchi, Atushi Taga, Noriaki Nagai

Pages: 379-386 Published online on: 06 November 2019

A novel ATRX mutation causes Smith‑Fineman‑Myers syndrome in a Chinese family

Liangshan Li, Jing Yu, Xiao Zhang, Mengmeng Han, Wenmiao Liu, Hui Li, Shiguo Liu

Pages: 387-392 Published online on: 12 November 2019

Inhibition of CYP1B1 ameliorates cardiac hypertrophy induced by uremic toxin

Ying Zhang, Shaobo Wang, Yinghui Huang, Ke Yang, Yong Liu, Xianjin Bi, Chi Liu, Jiachuan Xiong, Bo Zhang, Jinghong Zhao, Ling Nie

Pages: 393-404 Published online on: 11 November 2019

Histone 3 lysine 9 acetylation of BRG1 in the medial prefrontal cortex is associated with heroin self‑administration in rats

Qingxiao Hong, Jing Liu, Zi Lin, Dingding Zhuang, Wenjin Xu, Zemin Xu, Miaojun Lai, Huaqiang Zhu, Wenhua Zhou, Huifen Liu

Pages: 405-412 Published online on: 22 November 2019

Knockdown of PLCB2 expression reduces melanoma cell viability and promotes melanoma cell apoptosis by altering Ras/Raf/MAPK signals

Huahui Zhang, Tao Xie, Yongjie Shui, Yiying Qi

Pages: 420-428 Published online on: 06 November 2019

Lipoxin A4 attenuates hyperoxia‑induced lung epithelial cell injury via the upregulation of heme oxygenase‑1 and inhibition of proinflammatory cytokines

Yan‑Yan Luo, Sheng‑Hua Wu, Hong‑Yan Lu, Bing‑Jie Li, Shu‑Jun Li, Zhong‑Yi Sun, Rui Jin, Xiao‑Qing Chen

Pages: 429-437 Published online on: 15 November 2019

Identification of a novel pathogenic mutation of the MYH3 gene in a family with distal arthrogryposis type 2B

Wen‑Bo Wang, Ling‑Chi Kong, Rong‑Tai Zuo, Qing‑Lin Kang

Pages: 438-444 Published online on: 15 November 2019

IDO inhibitor synergized with radiotherapy to delay tumor growth by reversing T cell exhaustion

Meng Liu, Ziyang Li, Weirong Yao, Xiaoping Zeng, Lingyun Wang, Jiao Cheng, Bingyu Ma, Ruiqian Zhang, Weiping Min, Hongmei Wang

Pages: 445-453 Published online on: 12 November 2019

Blueberry anthocyanin‑enriched extract ameliorates transverse aortic constriction‑induced myocardial dysfunction via the DDAH1/ADMA/NO signaling pathway in mice

Weiqing Hu, Wenyue Wang, Qing Ma, Tao Liu, Jiefeng Zhang, Jicun Zhang

Pages: 454-462 Published online on: 06 November 2019

Protective effect of pyrrolidine dithiocarbamate on isoniazid/rifampicin‑induced liver injury in rats

Xue He, Yulin Song, Li Wang, Jianming Xu

Pages: 463-469 Published online on: 12 November 2019

Mechanical stress promotes biological functions of C2C12 myoblasts by activating PI3K/AKT/mTOR signaling pathway

Yu Da, Yongbin Mou, Mengjia Wang, Xiao Yuan, Fuhua Yan, Weidong Lan, Fang Zhang

Pages: 470-477 Published online on: 11 November 2019

rhBMP‑7 suppresses TGF‑β1‑induced endothelial to mesenchymal transition in circulating endothelial cells by regulating Smad5

Weili Ge, Yafei Mi, Shasha Xu, Tao Li, Yifei Lu, Jianjun Jiang

Pages: 478-484 Published online on: 21 November 2019

Organic anion transporting polypeptide 1A2 mediates fentanyl uptake in cultured cells

Xing‑Chen Huo, Hui‑Wen Yang, Li‑Hua Huang, Fan Zhang, Zi‑Ye Pan, Qin Liao

Pages: 485-492 Published online on: 05 November 2019

Brassicaphenanthrene A from Brassica rapa protects HT22 neuronal cells through the regulation of Nrf2‑mediated heme oxygenase‑1 expression

Hwan Lee, Wonmin Ko, Anisuzzaman Chowdhury, Bin Li, Sam Cheol Kim, Hyuncheol Oh, Youn‑Chul Kim, Eun‑Rhan Woo, Nam‑In Baek, Dong‑Sung Lee

Pages: 493-500 Published online on: 19 November 2019

Differentiation potential and functional properties of a CD34‑CD133+ subpopulation of endothelial progenitor cells

Katrin Bachelier, Carolin Bergholz, Erik B. Friedrich

Pages: 501-507 Published online on: 20 November 2019

Kai‑Xin‑San suppresses matrix metalloproteinases and myocardial apoptosis in rats with myocardial infarction and depression

Yuan Hu, Xianzhe Dong, Tianyi Zhang, Hongming Ma, Wenshan Yang, Yichen Wang, Ping Liu, Yibang Chen

Pages: 508-516 Published online on: 06 November 2019
Open Access

A novel gross deletion and breakpoint junction sequence analysis of ATP7B in a Chinese family with Wilson disease using next‑generation sequencing and Sanger sequencing

Wei‑Liang Liu, Fang Li, Lu Liu, Wei Chen, Zhi‑Xu He, Hao Gu, Rong Ai

Pages: 517-523 Published online on: 20 November 2019
Journal Cover

January 2020
Volume 21 Issue 1

Print ISSN: 1791-2997
Online ISSN: 1791-3004

Sign up for eToc alerts

Recommend to Library

Full Size Image