Lung cancer with dermatomyositis as the initial diagnosis: A case report

  • Authors:
    • Tiantian Zhang
    • Qiong Wu
    • Shukui Qin
    • Zishu Wang
    • Yawei Li
    • Rui Wang
    • Fang Su
  • View Affiliations

  • Published online on: May 2, 2019     https://doi.org/10.3892/mco.2019.1851
  • Pages: 59-62
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Abstract

It is well‑known that dermatomyositis (DM) is associated with a variety of malignancies, and the cancer‑specific mortality rate is high among patients who develop paraneoplastic DM. Paraneoplastic syndromes are described in ~10‑25% of adult patients with DM. Although paraneoplastic syndromes are associated with various malignancies, the most common is lung cancer, with different histological types of lung cancer being associated with different paraneoplastic syndromes. We herein report the case of a patient with lung cancer and DM, aiming to provide a useful guide to diagnosis and treatment by improving the understanding of these diseases for clinicians. Early detection, accurate diagnosis and timely treatment are crucial for prolonging patient survival.

References

1 

Silva JA, Mesquita Kde C, Igreja AC, Lucas IC, Freitas AF, Oliveira SM, Costa IM and Campbell IT: Paraneoplastic cutaneous manifestations: Concepts and updates. An Bras Dermatol. 88:9–22. 2013. View Article : Google Scholar : PubMed/NCBI

2 

Sterz G: Polymyositis. Berliner Klinische Wochenschrift. 53:4891916.

3 

Zhang X, Wang Y, Ma G, Zhang L, Jing H and Du J: Dermatomyositis as a symptom of primary lung cancer: A case report and review of the literature. Oncol Lett. 11:3413–3416. 2016. View Article : Google Scholar : PubMed/NCBI

4 

de Souza FH and Shinjo SK: Newly diagnosed dermatomyositis in the elderly as predictor of malignancy. Rev Bras Reumatol. 52:713–721. 2012.(In English, Portuguese).

5 

Zahr ZA and Baer AN: Malignancy in myositis. Curr Rheumatol Rep. 13:208–215. 2011. View Article : Google Scholar : PubMed/NCBI

6 

Miret M, Horváth-Puhó E, Déruaz-Luyet A, Sørensen HT and Ehrenstein V: Potential paraneoplastic syndromes and selected autoimmune conditions in patients with non-small cell lung cancer and small cell lung cancer: A population-based cohort study. PLoS One. 12:e01815642017. View Article : Google Scholar : PubMed/NCBI

7 

Porto L, Miranda M, Gomes A, André R and Rodrigues B: Paraneoplastic neurological syndrome as an initial indicator of small cell carcinoma of the lung. BMJ Case Rep. 2013:bcr20120084322013. View Article : Google Scholar : PubMed/NCBI

8 

Santacroce L: Paraneoplastic syndromes. Drugs & Diseases. 2017, simplehttps://emedicine.medscape.com/article/280744-overviewUpdated December 06 2018.

9 

Kanaji N, Watanabe N, Kita N, Bandoh S, Tadokoro A, Ishii T, Dobashi H and Matsunaga T: Paraneoplastic syndromes associated with lung cancer. World J Clin Oncol. 5:197–223. 2014. View Article : Google Scholar : PubMed/NCBI

10 

Sparsa A, Liozon E, Herrmann F, Ly K, Lebrun V, Soria P, Loustaud-Ratti V, Bouyssou-Gauthier ML, Boulinguez S, Bédane C, et al: Routine vs extensive malignancy search for adult dermatomyositis and polymyositis: A study of 40 patients. Arch Dermatol. 138:885–890. 2002. View Article : Google Scholar : PubMed/NCBI

11 

Basset-Seguin N, Roujeau JC, Gherardi R, Guillaume JC, Revuz J and Touraine R: Prognostic factors and predictive signs of malignancy in adult dermatomyositis. A study of 32 cases. Arch Dermatol. 126:633–637. 1990. View Article : Google Scholar : PubMed/NCBI

12 

Pelosof LC and Gerber DE: Paraneoplastic syndromes: An approach to diagnosis and treatment. Mayo Clin Proc. 85:838–854. 2010. View Article : Google Scholar : PubMed/NCBI

13 

Iorizzo LJ III and Jorizzo JL: The treatment and prognosis of dermatomyositis: An updated review. J Am Acad Dermatol. 59:99–112. 2008. View Article : Google Scholar : PubMed/NCBI

14 

Kovacs SO and Kovacs SC: Dermatomyositis. J Am Acad Dermatol. 39:899–920. 1998. View Article : Google Scholar : PubMed/NCBI

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July 2019
Volume 11 Issue 1

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Copy and paste a formatted citation
APA
Zhang, T., Wu, Q., Qin, S., Wang, Z., Li, Y., Wang, R., & Su, F. (2019). Lung cancer with dermatomyositis as the initial diagnosis: A case report. Molecular and Clinical Oncology, 11, 59-62. https://doi.org/10.3892/mco.2019.1851
MLA
Zhang, T., Wu, Q., Qin, S., Wang, Z., Li, Y., Wang, R., Su, F."Lung cancer with dermatomyositis as the initial diagnosis: A case report". Molecular and Clinical Oncology 11.1 (2019): 59-62.
Chicago
Zhang, T., Wu, Q., Qin, S., Wang, Z., Li, Y., Wang, R., Su, F."Lung cancer with dermatomyositis as the initial diagnosis: A case report". Molecular and Clinical Oncology 11, no. 1 (2019): 59-62. https://doi.org/10.3892/mco.2019.1851