Journal Articles

Open Access

Melatonin prevents sepsis-induced renal injury via the PINK1/Parkin1 signaling pathway

Wenling Dai, Haifeng Huang, Linjie Si, Shi Hu, Liangliang Zhou, Lingling Xu, Yijun Deng

Pages: 1197-1204 Published online on: 07 August 2019
Open Access

Identification of candidate genes and miRNAs associated with neuropathic pain induced by spared nerve injury

He Li, Hong‑Quan Wan, Hai‑Jun Zhao, Shu‑Xin Luan, Chun‑Guo Zhang

Pages: 1205-1218 Published online on: 06 August 2019
Open Access

MicroRNA-29a suppresses the invasion and migration of osteosarcoma cells by regulating the SOCS1/NF-κB signalling pathway through negatively targeting DNMT3B

Hao‑Li Gong, Ye Tao, Xin‑Zhan Mao, De‑Ye Song, Di You, Jiang‑Dong Ni

Pages: 1219-1232 Published online on: 24 July 2019
Open Access

Characteristic genes in THP‑1 derived macrophages infected with Mycobacterium tuberculosis H37Rv strain identified by integrating bioinformatics methods

Yu‑Wei Zhang, Yan Lin, Hui‑Yuan Yu, Ruo‑Nan Tian, Fan Li

Pages: 1243-1254 Published online on: 30 July 2019
Open Access

Neuregulin‑1 protects cardiac function in septic rats through multiple targets based on endothelial cells

Wen Kang, Yue Cheng, Fang Zhou, Long Wang, Liang Zhong, Hai Tao Li, Xi Wang, Song Dang, Xin Wang

Pages: 1255-1266 Published online on: 08 August 2019
Open Access

miRNA profile obtained by next‑generation sequencing in metastatic breast cancer patients is able to predict the response to systemic treatments

Antonio Daniel Martinez‑Gutierrez, Oliver Millan Catalan, Rafael Vázquez‑Romo, Fany Iris Porras Reyes, Alberto Alvarado‑Miranda, Fernando Lara Medina, Juan E. Bargallo‑Rocha, Luz Tonatzin Orozco Moreno, David Cantú De León, Luis Alonso Herrera, César López‑Camarillo, Carlos Pérez‑Plasencia, Alma D. Campos‑Parra

Pages: 1267-1280 Published online on: 30 July 2019
Open Access

Aspirin alleviates orthopedic implant‑associated infection

Yi Jiang, Sheng‑Nan Wang, Hang‑Tian Wu, Han‑Jun Qin, Ming‑Liang Ren, Jian‑Chun Lin, Bin Yu

Pages: 1281-1288 Published online on: 02 August 2019
Open Access

Simvastatin promotes endothelial dysfunction by activating the Wnt/β‑catenin pathway under oxidative stress

Zhiqiang He, Xinyue Du, Yifan Wu, Lingyue Hua, Linxi Wan, Nianlong Yan

Pages: 1289-1298 Published online on: 09 August 2019
Open Access

Inflammasome activity in leucocytes decreases with abdominal aortic aneurysm progression

Philipp Erhart, Sinan Cakmak, Caspar Grond‑Ginsbach, Maani Hakimi, Dittmar Böckler, Susanne Dihlmann

Pages: 1299-1308 Published online on: 07 August 2019
Open Access

Hydrogen alleviates mitochondrial dysfunction and organ damage via autophagy‑mediated NLRP3 inflammasome inactivation in sepsis

Hongguang Chen, Xing Mao, Xiaoyin Meng, Yuan Li, Jingcheng Feng, Linlin Zhang, Yang Zhang, Yaoqi Wang, Yonghao Yu, Keliang Xie

Pages: 1309-1324 Published online on: 13 August 2019
Open Access

Upregulation of eukaryotic translation initiation factor 4E associates with a poor prognosis in gallbladder cancer and promotes cell proliferation in vitro and in vivo

Debao Fang, Jing Peng, Guobing Wang, Dachen Zhou, Xiaoping Geng

Pages: 1325-1332 Published online on: 19 August 2019
Open Access

Effect of astragalosides on long non-coding RNA expression profiles in rats with adjuvant-induced arthritis

Hui Jiang, Fu‑Rong Wu, Jian Liu, Xiu‑Juan Qin, Nan‑Nan Jiang, Wei‑Ping Li

Pages: 1344-1356 Published online on: 22 July 2019
Open Access

Knockdown of miR-222 inhibits inflammation and the apoptosis of LPS-stimulated human intervertebral disc nucleus pulposus cells

Yang Zhang, Jiujie Yang, Xiaoqing Zhou, Nan Wang, Zhi Li, Yubo Zhou, Jianzhou Feng, Dewei Shen, Wei Zhao

Pages: 1357-1365 Published online on: 16 August 2019
Open Access

Impact of single nucleotide polymorphisms in the VEGFR2 gene on endothelial cell activation under non‑uniform shear stress

Nora M. Schacher, Dorette Raaz‑Schrauder, Francesca Pasutto, Florian M. Stumpfe, Miyuki Tauchi, Barbara Dietel, Stephan Achenbach, Katharina Urschel

Pages: 1366-1376 Published online on: 05 August 2019
Open Access

Dissociation of HKII in retinal epithelial cells induces oxidative stress injury in the retina

Liqun Chu, Lin Xiao, Bing Xu, Jingmei Xu

Pages: 1377-1387 Published online on: 06 August 2019
Open Access

Targeting Notch-activated M1 macrophages attenuate lung tissue damage in a rat model of ventilator induced lung injury

Danping Yin, Weiming Wang, Wei Han, Chen Fan

Pages: 1388-1398 Published online on: 16 August 2019
Open Access

Differential expression of circRNAs during rat lung development

Yan‑Qing Shen, Jing‑Jing Pan, Zhong‑Yi Sun, Xiao‑Qing Chen, Xiao‑Guang Zhou, Xiao‑Yu Zhou, Rui Cheng, Yang Yang

Pages: 1399-1413 Published online on: 02 August 2019
Open Access

Partial decortication ameliorates dopamine depletion‑induced striatal neuron lesions in rats

Yaofeng Zhu, Bingbing Liu, Xuefeng Zheng, Jiajia Wu, Si Chen, Zhi Chen, Tao Chen, Ziyun Huang, Wanlong Lei

Pages: 1414-1424 Published online on: 25 July 2019
Open Access

Human amnion mesenchymal stem cells attenuate atherosclerosis by modulating macrophage function to reduce immune response

Xiufang Wei, Guang Sun, Xiaoxue Zhao, Qianqian Wu, Ling Chen, Yichi Xu, Xining Pang, Guoxian Qi

Pages: 1425-1435 Published online on: 23 July 2019
Open Access

Next-generation sequencing predicts interaction network between miRNA and target genes in lipoteichoic acid-stimulated human neutrophils

Meng‑Chi Yen, I‑Jeng Yeh, Kuan‑Ting Liu, Shu‑Fang Jian, Chia‑Jung Lin, Ming‑Ju Tsai, Po‑Lin Kuo

Pages: 1436-1446 Published online on: 31 July 2019
Open Access

Identification of differentially expressed genes and preliminary validations in cardiac pathological remodeling induced by transverse aortic constriction

Hui‑Bo Wang, Rong Huang, Kang Yang, Man Xu, Di Fan, Ming‑Xin Liu, Si‑Hui Huang, Li‑Bo Liu, Hai‑Ming Wu, Qi‑Zhu Tang

Pages: 1447-1461 Published online on: 30 July 2019
Open Access

Identification of circular RNAs hsa_circ_0044235 and hsa_circ_0068367 as novel biomarkers for systemic lupus erythematosus

Qing Luo, Lu Zhang, Xue Li, Biqi Fu, Yang Guo, Zikun Huang, Junming Li

Pages: 1462-1472 Published online on: 05 August 2019
Open Access

Axonal sprouting in the dorsal cochlear nucleus affects gap‑prepulse inhibition following noise exposure

Kyu‑Hee Han, Seog‑Kyun Mun, Seonyong Sohn, Xian‑Yu Piao, Ilyong Park, Munyoung Chang

Pages: 1473-1483 Published online on: 19 August 2019
Open Access

Irradiation enhances the therapeutic effect of the oncolytic adenovirus XVir-N-31 in brain tumor initiating cells

Rebecca Czolk, Niklas Schwarz, Henner Koch, Sonja Schötterl, Thomas V. Wuttke, Per S. Holm, Stephan M. Huber, Ulrike Naumann

Pages: 1484-1494 Published online on: 31 July 2019

Altered expression of glucose metabolism associated genes in a tacrolimus‑induced post‑transplantation diabetes mellitus in rat model

Ling Zhang, Yunqiang He, Cunzao Wu, Minmin Wu, Xuehai Chen, Jiao Luo, Yong Cai, Peng Xia, Bicheng Chen

Pages: 1495-1504 Published online on: 16 August 2019

MicroRNA-26a targets the mdm2/p53 loop directly in response to liver regeneration

Jian Zhou, Zhuoyuan Li, Yingbin Huang, Weiqiang Ju, Dongping Wang, Xiaofeng Zhu, Xiaoshun He

Pages: 1505-1514 Published online on: 22 July 2019

L‑carnitine alleviates oxidative stress‑related damage via MAPK signaling in human lens epithelial cells exposed to H2O2

Xiaoxia Li, Fanlan Meng, Hua Li, Xia Hua, Li'an Wu, Xiaoyong Yuan

Pages: 1515-1522 Published online on: 22 July 2019

Green tea polyphenols attenuate hepatic steatosis, and reduce insulin resistance and inflammation in high-fat diet-induced rats

Hong‑Miao Xia, Jin Wang, Xiao‑Jie Xie, Li‑Juan Xu, Shi‑Qi Tang

Pages: 1523-1530 Published online on: 23 July 2019

Hydroxytyrosol promotes autophagy by regulating SIRT1 against advanced oxidation protein product‑induced NADPH oxidase and inflammatory response

Tian Sun, Qian Chen, Si‑Yuan Zhu, Qian Wu, Cong‑Rui Liao, Zheng Wang, Xiao‑Hu Wu, Hang‑Tian Wu, Jian‑Ting Chen

Pages: 1531-1540 Published online on: 05 August 2019

Artesunate alleviates interleukin‑1β‑induced inflammatory response and apoptosis by inhibiting the NF‑κB signaling pathway in chondrocyte‑like ATDC5 cells, and delays the progression of osteoarthritis in a mouse model

Yicheng Li, Wenbo Mu, Jiangdong Ren, Shalitanati Wuermanbieke, Tuerhongjiang Wahafu, Baochao Ji, Hairong Ma, Abdusami Amat, Keyuan Zhang, Li Cao

Pages: 1541-1551 Published online on: 26 July 2019

Induction of ROS‑mediated cell death and activation of the JNK pathway by a sulfonamide derivative

Rehan Ahmad, Mansoor‑Ali Vaali‑Mohammed, Mohammed Elwatidy, Omar Al‑Obeed, Khayal Al‑Khayal, Wagdy M. Eldehna, Hatem A. Abdel‑Aziz, Ahmed Alafeefy, Maha Abdulla

Pages: 1552-1562 Published online on: 23 July 2019

Icariin attenuates the severity of cerulein‑induced acute pancreatitis by inhibiting p38 activation in mice

Dong‑Uk Kim, Gi‑Sang Bae, Myoung‑Jin Kim, Ji‑Won Choi, Dong‑Gu Kim, Ho‑Joon Song, Sung‑Joo Park

Pages: 1563-1573 Published online on: 16 August 2019

Novel Notch signaling inhibitor NSI‑1 suppresses nuclear translocation of the Notch intracellular domain

Takaya Shiraishi, Masahiro Sakaitani, Satoko Otsuguro, Katsumi Maenaka, Toshiharu Suzuki, Tadashi Nakaya

Pages: 1574-1584 Published online on: 19 July 2019

KCNMB3 in spinal microglia contributes to the generation and maintenance of neuropathic pain in mice

Kazuhisa Imari, Yuka Harada, Jing Zhang, Yoshihide Mori, Yoshinori Hayashi

Pages: 1585-1593 Published online on: 19 July 2019
Open Access

[Corrigendum] MicroRNA‑497 inhibits multiple myeloma growth and increases susceptibility to bortezomib by targeting Bcl‑2

Faqing Tian, Yong Zhan, Wei Zhu, Juheng Li, Meiqin Tang, Xiaohui Chen, Jian Jiang

Pages: 1594-1594 Published online on: 02 August 2019
Open Access

[Corrigendum] Preparation and biological evaluation of a novel pH-sensitive poly (β-malic acid) conjugate for antitumor drug delivery

Youbei Qiao, Bao Liu, Yifan Peng, Erlong Ji, Hong Wu

Pages: 1595-1595 Published online on: 07 August 2019
Journal Cover

October 2019
Volume 44 Issue 4

Print ISSN: 1107-3756
Online ISSN: 1791-244X

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