Journal Articles

Open Access

[Editorial] COVID‑19: Post‑lockdown guidelines

Ronald N. Kostoff, Michael B. Briggs, Alan L. Porter, Michael Aschner, Demetrios A. Spandidos, Aristidis Tsatsakis

Pages: 463-466 Published online on: 12 June 2020
Open Access

Comprehensive analysis of drugs to treat SARS‑CoV‑2 infection: Mechanistic insights into current COVID‑19 therapies (Review)

George Mihai Nitulescu, Horia Paunescu, Sterghios A. Moschos, Dimitrios Petrakis, Georgiana Nitulescu, George Nicolae Daniel Ion, Demetrios A. Spandidos, Taxiarchis Konstantinos Nikolouzakis, Nikolaos Drakoulis, Aristidis Tsatsakis

Pages: 467-488 Published online on: 18 May 2020
Open Access

A dissection of SARS‑CoV2 with clinical implications (Review)

Felician Stancioiu, Georgios Z. Papadakis, Stelios Kteniadakis, Boris Nikovaevich Izotov, Michael D. Coleman, Demetrios A. Spandidos, Aristidis Tsatsakis

Pages: 489-508 Published online on: 10 June 2020
Open Access

Update on current views and advances on RSV infection (Review)

Ioannis N. Mammas, Simon B. Drysdale, Barbara Rath, Maria Theodoridou, Georgia Papaioannou, Alexia Papatheodoropoulou, Eirini Koutsounaki, Chryssie Koutsaftiki, Eleftheria Kozanidou, Vassilis Achtsidis, Paraskevi Korovessi, George P. Chrousos, Demetrios A. Spandidos

Pages: 509-520 Published online on: 15 June 2020
Open Access

Advance genome editing technologies in the treatment of human diseases: CRISPR therapy (Review)

Meryem Alagoz, Nasim Kherad

Pages: 521-534 Published online on: 19 May 2020
Open Access

Placental exosomes isolated from urine of patients with gestational diabetes exhibit a differential profile expression of microRNAs across gestation

Ana Sofía Herrera-Van Oostdam, Juan Carlos Toro‑Ortíz, Jesús Adrián López, Daniel E. Noyola, David Alejandro García‑López, Noé Valentín Durán‑Figueroa, Eduardo Martínez‑Martínez, Diana P. Portales‑Pérez, Mariana Salgado‑Bustamante, Yamilé López‑Hernández

Pages: 546-560 Published online on: 03 June 2020
Open Access

LINC00473 contributes to the radioresistance of esophageal squamous cell carcinoma by regulating microRNA‑497‑5p and cell division cycle 25A

Wei‑Hua Liu, Han‑Yong Qiao, Jian Xu, Wei‑Qing Wang, Yi‑Lei Wu, Xia Wu

Pages: 571-582 Published online on: 25 May 2020
Open Access

Decitabine attenuates dextran sodium sulfate‑induced ulcerative colitis through regulation of immune regulatory cells and intestinal barrier

Chang Su, Shaoqun Liu, Xiaoying Ma, Xiaotong Yang, Jianwen Liu, Peiyong Zheng, Yiou Cao

Pages: 583-594 Published online on: 18 May 2020
Open Access

Fibroblast‑derived exosomal microRNA‑369 potentiates migration and invasion of lung squamous cell carcinoma cells via NF1‑mediated MAPK signaling pathway

Liping Guo, Baoli Li, Jianjun Yang, Juan Shen, Jinshan Ji, Meijing Miao

Pages: 595-608 Published online on: 22 May 2020
Open Access

Circular RNA derived from TIMP2 functions as a competitive endogenous RNA and regulates intervertebral disc degeneration by targeting miR‑185‑5p and matrix metalloproteinase 2

Wei Guo, Bin Zhang, Chao Sun, Hui‑Quan Duan, Wei‑Xiao Liu, Kun Mu, Ling Zhao, Hao‑Ran Li, Zhan‑Yin Dong, Qing Cui

Pages: 621-632 Published online on: 29 May 2020
Open Access

Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts

Yanfei Du, Haiying Xiao, Jun Wan, Xinyu Wang, Tao Li, Shuzhan Zheng, Jian Feng, Qiang Ye, Jiafu Li, Guang Li, Zhongcai Fan

Pages: 633-640 Published online on: 18 May 2020
Open Access

IL‑27 suppresses airway inflammation, hyperresponsiveness and remodeling via the STAT1 and STAT3 pathways in mice with allergic asthma

Degan Lu, Jiameng Lu, Xiaoqing Ji, Yanbo Ji, Zewen Zhang, Haiying Peng, Fei Sun, Caiqing Zhang

Pages: 641-652 Published online on: 29 May 2020
Open Access

Silencing of long non‑coding antisense RNA brain‑derived neurotrophic factor attenuates hypoxia/ischemia‑induced neonatal brain injury

Li‑Xing Qiao, Rui‑Bin Zhao, Ming‑Fu Wu, Li‑Hua Zhu, Zheng‑Kun Xia

Pages: 653-662 Published online on: 02 June 2020
Open Access

TRAP1 attenuates H9C2 myocardial cell injury induced by extracellular acidification via the inhibition of MPTP opening

Lingxiao Zhang, Lerong Liu, Xia Li, Xing Zhang, Jiangpei Zhao, Yuanyuan Luo, Xiangyu Guo, Tongfeng Zhao

Pages: 663-674 Published online on: 04 June 2020
Open Access

Knockdown of Tousled‑like kinase 1 inhibits survival of glioblastoma multiforme cells

Kamariah Ibrahim, Nor Azian Abdul Murad, Roslan Harun, Rahman Jamal

Pages: 685-699 Published online on: 28 May 2020
Open Access

Rotenone restrains colon cancer cell viability, motility and epithelial‑mesenchymal transition and tumorigenesis in nude mice via the PI3K/AKT pathway

Wenbo Xiao, Yongwei Liu, Maolin Dai, Yu Li, Renqun Peng, Shuangjiang Yu, Hao Liu

Pages: 700-708 Published online on: 10 June 2020
Open Access

Ribonuclease T2 from Aspergillus fumigatus promotes T helper type 2 responses through M2 polarization of macrophages

Jia‑Jie Chen, Yong‑Shen He, Xiao‑Jun Zhong, Ze‑Lang Cai, Yan‑Si Lyu, Zhen‑Fu Zhao, Kunmei Ji

Pages: 718-728 Published online on: 21 May 2020
Open Access

lncRNA DGCR 5/miR‑27a‑3p/BNIP3 promotes cell apoptosis in pancreatic cancer by regulating the p38 MAPK pathway

Xianjie Li, Shanxue Zhou, Tianyi Fan, Xuefeng Feng

Pages: 729-739 Published online on: 04 June 2020
Open Access

Simvastatin inhibits the adipogenesis of bone marrow‑derived mesenchymal stem cells through the downregulation of chemerin/CMKLR1 signaling

Yao Guo, Jianzhong Huo, Dou Wu, Haihu Hao, Xinghua Ji, Enzhe Zhao, Boyuan Nie, Qiang Liu

Pages: 751-761 Published online on: 18 May 2020
Open Access

Hypercapnia exacerbates the disruption of the blood‑brain barrier by inducing interleukin‑1β overproduction in the blood of hypoxemic adult rats

Hongguang Ding, Xinqiang Liu, Xusheng Li, Miaoyun Wen, Ya Li, Yongli Han, Linqiang Huang, Mengting Liu, Hongke Zeng

Pages: 762-772 Published online on: 14 May 2020
Open Access

Hyperoxia reduces STX17 expression and inhibits the autophagic flux in alveolar type II epithelial cells in newborn rats

Dan Zhang, Xinyi Zhao, Dingning Zhang, Siyang Gao, Xindong Xue, Jianhua Fu

Pages: 773-781 Published online on: 27 May 2020
Open Access

Upregulation of Nav1.7 by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain

Jun-Jie Tian, Chao-Yang Tan, Qin-Yi Chen, Ying Zhou, Zu-Wei Qu, Meng Zhang, Ke-Tao Ma, Wen-Yan Shi, Li Li, Jun-Qiang Si

Pages: 782-794 Published online on: 20 May 2020
Open Access

Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation

Kazi Mohammad Ali Zinnah, Jae‑Won Seol, Sang‑Youel Park

Pages: 795-805 Published online on: 05 June 2020
Open Access

Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang

Pages: 806-816 Published online on: 04 June 2020
Open Access

Inhibitory effects of brusatol delivered using glycosaminoglycan‑placental chondroitin sulfate A‑modified nanoparticles on the proliferation, migration and invasion of cancer cells

Xin Chen, Tailang Yin, Baozhen Zhang, Beini Sun, Jie Chen, Tianxia Xiao, Baobei Wang, Mengxia Li, Jing Yang, Xiujun Fan

Pages: 817-827 Published online on: 03 June 2020

CTBP1‑AS2 inhibits proliferation and induces autophagy in ox‑LDL‑stimulated vascular smooth muscle cells by regulating miR‑195‑5p/ATG14

Yang Wang, Cheng‑Xin Zhang, Sheng‑Lin Ge, Wen‑Hui Gong

Pages: 839-848 Published online on: 02 June 2020

Preliminary research on the effects and mechanisms of umbilical cord‑derived mesenchymal stem cells in streptozotocin‑induced diabetic retinopathy

Ken Zhao, Jie Liu, Gang Dong, Huan Xia, Pingan Wang, Xuan Xiao, Zhen Chen

Pages: 849-858 Published online on: 01 June 2020

Long non‑coding RNA RP11‑340F14.6 promotes a shift in the Th17/Treg ratio by binding with P2X7R in juvenile idiopathic arthritis

Na Huang, Zhidan Fan, Le Ma, Huihui Ma, Hui Huang, Haiguo Yu, Xiaoyu Zhou

Pages: 859-868 Published online on: 27 May 2020

Recombinant programmed cell death 1 inhibits psoriatic inflammation in imiquimod‑treated mice

Shiguang Peng, Mei Cao, Xiaoying Sun, Yaqiong Zhou, Chu‑Yen Chen, Tian Ma, Hongjin Li, Bin Li, Bo Zhu, Xin Li

Pages: 869-879 Published online on: 21 May 2020

IL‑18 knockout alleviates atopic dermatitis‑like skin lesions induced by MC903 in a mouse model

Jia‑Long Chen, Xue‑Li Niu, Ya‑Li Gao, Lei Ma, Xing‑Hua Gao, Hong‑Duo Chen, Rui‑Qun Qi

Pages: 880-888 Published online on: 04 June 2020

Sevoflurane preconditioning inhibits cardiomyocyte injury induced by oxygen‑glucose deprivation by modulating TXNIP

Meina Ma, Rui Li, Wenbo Sun, Qi Wang, Hong Yu, Hongmei Yu

Pages: 889-897 Published online on: 11 June 2020
Journal Cover

August-2020
Volume 46 Issue 2

Print ISSN: 1107-3756
Online ISSN: 1791-244X

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