Open Access

Recent progress regarding kaempferol for the treatment of various diseases (Review)

  • Authors:
    • Jie Ren
    • Yifei Lu
    • Yanhong Qian
    • Bozhou Chen
    • Tao Wu
    • Guang Ji
  • View Affiliations

  • Published online on: August 13, 2019     https://doi.org/10.3892/etm.2019.7886
  • Pages: 2759-2776
  • Copyright: © Ren et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Kaempferol, also known as kaempferol‑3 or kaempferide, is a flavonoid compound that naturally occurs in tea, as well as numerous common vegetables and fruits, including beans, broccoli, cabbage, gooseberries, grapes, kale, strawberries, tomatoes, citrus fruits, brussel sprouts, apples and grapefruit. The present review mainly summarizes the application of kaempferol in treating diseases and the underlying mechanisms that are currently being studied. Due to its anti‑inflammatory properties, it may be used to treat numerous acute and chronic inflammation‑induced diseases, including intervertebral disc degeneration and colitis, as well as post‑menopausal bone loss and acute lung injury. In addition, it has beneficial effects against cancer, liver injury, obesity and diabetes, inhibits vascular endothelial inflammation, protects the cranial nerve and heart function, and may be used for treating fibroproliferative disorders, including hypertrophic scar

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October 2019
Volume 18 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
APA
Ren, J., Lu, Y., Qian, Y., Chen, B., Wu, T., & Ji, G. (2019). Recent progress regarding kaempferol for the treatment of various diseases (Review). Experimental and Therapeutic Medicine, 18, 2759-2776. https://doi.org/10.3892/etm.2019.7886
MLA
Ren, J., Lu, Y., Qian, Y., Chen, B., Wu, T., Ji, G."Recent progress regarding kaempferol for the treatment of various diseases (Review)". Experimental and Therapeutic Medicine 18.4 (2019): 2759-2776.
Chicago
Ren, J., Lu, Y., Qian, Y., Chen, B., Wu, T., Ji, G."Recent progress regarding kaempferol for the treatment of various diseases (Review)". Experimental and Therapeutic Medicine 18, no. 4 (2019): 2759-2776. https://doi.org/10.3892/etm.2019.7886