Open Access

Rapid progression and recovery of massive gastric mucosal damage complicated by Henoch‑Schönlein purpura in a patient with liver cirrhosis: A case report

  • Authors:
    • Tae‑Geun Gweon
    • Jung Hyun Kwon
  • View Affiliations

  • Published online on: July 26, 2019     https://doi.org/10.3892/etm.2019.7815
  • Pages: 2051-2054
  • Copyright: © Gweon et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Endoscopic findings associated with gastric ischemia include friable gastric mucosa, irregular ulceration, petechiae and purpura. The etiology of gastric ischemia includes shock, sepsis, thrombosis, embolism and vasculitis. Henoch‑Schönlein purpura (HSP) is a leukocytoclastic vasculitis that affects small vessels in the skin, kidney and gastrointestinal (GI) tract. Rapid progression of HSP manifested with acute gastric mucosal bleeding has been rarely reported. The present case study reports on a patient who had undergone endoscopic variceal ligation for esophageal varix bleeding and the gastric mucosa exhibited no evidence of HSP. After 9 days, reexamination using endoscopy to check for new‑onset hematemesis revealed massive necrosis in the gastric mucosa, friable mucosal tissue and acute ischemic GI bleeding. The patient was treated with corticosteroid injections for 7 days, which caused a marked regression of the hemorrhagic gastric mucosa. The present case study reported on this patient with acute GI bleeding caused by HSP who was successfully treated with corticosteroids.

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September 2019
Volume 18 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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APA
Gweon, T., & Gweon, T. (2019). Rapid progression and recovery of massive gastric mucosal damage complicated by Henoch‑Schönlein purpura in a patient with liver cirrhosis: A case report. Experimental and Therapeutic Medicine, 18, 2051-2054. https://doi.org/10.3892/etm.2019.7815
MLA
Gweon, T., Kwon, J. H."Rapid progression and recovery of massive gastric mucosal damage complicated by Henoch‑Schönlein purpura in a patient with liver cirrhosis: A case report". Experimental and Therapeutic Medicine 18.3 (2019): 2051-2054.
Chicago
Gweon, T., Kwon, J. H."Rapid progression and recovery of massive gastric mucosal damage complicated by Henoch‑Schönlein purpura in a patient with liver cirrhosis: A case report". Experimental and Therapeutic Medicine 18, no. 3 (2019): 2051-2054. https://doi.org/10.3892/etm.2019.7815