Open Access

Gestational weight management and pregnancy outcomes among women of advanced maternal age

  • Authors:
    • Juan Lin
    • Yuelin Fu
    • Qing Han
    • Jianying Yan
    • Rongxin Chen
    • Huale Zhang
  • View Affiliations

  • Published online on: July 9, 2019     https://doi.org/10.3892/etm.2019.7752
  • Pages: 1723-1728
  • Copyright: © Lin et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

In this study, we assessed the effects of pre‑pregnancy body mass index (BMI) and gestational weight gain (GWG) on the pregnancy outcomes of women of advanced age using a back‑propagation (BP) artificial neural network. We conducted a retrospective analysis on postpartum and hospital delivery data from 1,015 women of advanced maternal age (AMA) hospitalized at the Fujian Provincial Maternity and Children's Hospital from January to June, 2017. Pre‑pregnancy overweight was found to increase the incidence of gestational diabetes mellitus (GDM), hypertensive disorders complicating pregnancy (HDCP) and fetal macrosomia. In addition, poor weight gain during pregnancy increased the chances of pre-term births (PTBs). Furthermore, excessive weight gain during pregnancy increased the incidence of macrosomia in women of AMA. On the whole, the findings of this study suggest that controlling the pre‑pregnancy BMI and the GWG may reduce the incidence of adverse pregnancy outcomes in women of AMA. The BP neural network is suitable for the study of weight changes in this population.

References

1 

Chen Y, Zheng XL, Wu SW and Zhang WY: Clinic characteristics of women with advanced maternal age and perinatal outcomes. Zhonghua Fu Chan Ke Za Zhi. 52:508–513. 2017.(In Chinese). PubMed/NCBI

2 

Dong B, Yu H, Wei Q, Zhi M, Wu C, Zhu X and Li L: The effect of pre-pregnancy body mass index and excessive gestational weight gain on the risk of gestational diabetes in advanced maternal age. Oncotarget. 8:58364–58371. 2017.PubMed/NCBI

3 

Wang C, Wang XY and Yang HX: Effect of maternal age on pregnancy outcomes in Beijing. Zhonghua Fu Chan Ke Za Zhi. 52:514–520. 2017.PubMed/NCBI

4 

Yang S, Peng A, Wei S, Wu J, Zhao J, Zhang Y, Wang J, Lu Y, Yu Y and Zhang B: Pre-Pregnancy Body Mass Index, Gestational Weight Gain, and Birth Weight: A Cohort Study in China. PLoS One. 10:e01301012015. View Article : Google Scholar : PubMed/NCBI

5 

Hill B, McPhie S, Moran LJ, Harrison P, Huang TT-K, Teede H and Skouteris H: Lifestyle intervention to prevent obesity during pregnancy: Implications and recommendations for research and implementation. Midwifery. 49:13–18. 2017. View Article : Google Scholar : PubMed/NCBI

6 

Di Mascio D, Magro-Malosso ER, Saccone G, Marhefka GD and Berghella V: Exercise during pregnancy in normal-weight women and risk of preterm birth: a systematic review and meta-analysis of randomized controlled trials. Am J Obstet Gynecol. 215:561–571. 2016. View Article : Google Scholar : PubMed/NCBI

7 

Institute of Medicine (US) and National Research Council (US) Committee to Reexamine IOM Pregnancy Weight Guidelines, . Rasmussen KM and Yaktine AL: Weight Gain During Pregnancy: Reexamining the Guidelines. National Academies Press; Washington, DC: 2009

8 

Jin D and Lin S: Brief introduction of back propagation (BP) neural network algorithm and its improvement. Advances in Computer Science and Information Engineering. Springer; Berlin, Heidelberg: pp. 553–558. 2012

9 

Yang S, Zhou A, Xiong C, Yang R, Bassig BA, Hu R, Zhang Y, Yao C, Zhang Y, Qiu L, et al: Parental body mass index, gestational weight gain, and risk of macrosomia: A population-based case-control study in China. Paediatr Perinat Epidemiol. 29:462–471. 2015. View Article : Google Scholar : PubMed/NCBI

10 

Bautista-Castaño I, Henriquez-Sanchez P, Alemán-Perez N, Garcia-Salvador JJ, Gonzalez-Quesada A, García-Hernández JA and Serra-Majem L: Maternal obesity in early pregnancy and risk of adverse outcomes. PLoS One. 8:e804102013. View Article : Google Scholar : PubMed/NCBI

11 

Liu L, Hong Z and Zhang L: Associations of prepregnancy body mass index and gestational weight gain with pregnancy outcomes in nulliparous women delivering single live babies. Sci Rep. 5:128632015. View Article : Google Scholar : PubMed/NCBI

12 

Helseth R, Salvesen O, Stafne SN, Mørkved S, Salvesen KA and Carlsen SM: Gestational diabetes mellitus among Nordic Caucasian women: Prevalence and risk factors according to WHO and simplified IADPSG criteria. Scand J Clin Lab Invest. 74:620–628. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Roberts JM, Bodnar LM, Patrick TE and Powers RW: The role of οbesity in πreeclampsia. Pregnancy Hypertens. 1:6–16. 2011. View Article : Google Scholar : PubMed/NCBI

14 

Schummers L, Hutcheon JA, Bodnar LM, Lieberman E and Himes KP: Risk of adverse pregnancy outcomes by prepregnancy body mass index: A population-based study to inform prepregnancy weight loss counseling. Obstet Gynecol. 125:133–143. 2015. View Article : Google Scholar : PubMed/NCBI

15 

Huang A, Ji Z, Zhao W, Hu H, Yang Q and Chen D: Rate of gestational weight gain and preterm birth in relation to prepregnancy body mass indices and trimester: A follow-up study in China. Reprod Health. 13:932016. View Article : Google Scholar : PubMed/NCBI

16 

Drehmer M, Duncan BB, Kac G and Schmidt MI: Association of second and third trimester weight gain in pregnancy with maternal and fetal outcomes. PLoS One. 8:e547042013. View Article : Google Scholar : PubMed/NCBI

17 

Liu P, Xu L, Wang Y, Zhang Y, Du Y, Sun Y and Wang Z: Association between perinatal outcomes and maternal pre-pregnancy body mass index. Obes Rev. 17:1091–1102. 2016. View Article : Google Scholar : PubMed/NCBI

18 

Wang S, Ge X, Zhu B, Xuan Y, Huang K, Rutayisire E, Mao L, Huang S, Yan S and Tao F: Maternal continuing folic acid supplementation after the first trimester of pregnancy increased the risk of large-for-gestational-age birth: A Population-Based Birth Cohort Study. Nutrients. 8:82016. View Article : Google Scholar

19 

Gaillard R, Durmuş B, Hofman A, Mackenbach JP, Steegers EA and Jaddoe VW: Risk factors and outcomes of maternal obesity and excessive weight gain during pregnancy. Obesity (Silver Spring). 21:1046–1055. 2013. View Article : Google Scholar : PubMed/NCBI

20 

Goldstein RF, Abell SK, Ranasinha S, Misso M, Boyle JA, Black MH, Li N, Hu G, Corrado F, Rode L, et al: Association of gestational weight gain with maternal and infant outcomes: A systematic review and meta-analysis. JAMA317. 2207–2225. 2017.

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September 2019
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Copy and paste a formatted citation
APA
Lin, J., Fu, Y., Han, Q., Yan, J., Chen, R., & Zhang, H. (2019). Gestational weight management and pregnancy outcomes among women of advanced maternal age. Experimental and Therapeutic Medicine, 18, 1723-1728. https://doi.org/10.3892/etm.2019.7752
MLA
Lin, J., Fu, Y., Han, Q., Yan, J., Chen, R., Zhang, H."Gestational weight management and pregnancy outcomes among women of advanced maternal age". Experimental and Therapeutic Medicine 18.3 (2019): 1723-1728.
Chicago
Lin, J., Fu, Y., Han, Q., Yan, J., Chen, R., Zhang, H."Gestational weight management and pregnancy outcomes among women of advanced maternal age". Experimental and Therapeutic Medicine 18, no. 3 (2019): 1723-1728. https://doi.org/10.3892/etm.2019.7752