Open Access

Application value of procalcitonin, C‑reactive protein and interleukin‑6 in the evaluation of traumatic shock

  • Authors:
    • Yang Li
    • Ling Chen
    • Wenge Fang
    • Huihong Chen
  • View Affiliations

  • Published online on: April 16, 2019     https://doi.org/10.3892/etm.2019.7492
  • Pages: 4586-4592
  • Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Procalcitonin (PCT), C‑reactive protein (CRP) and interleukin‑6 (IL‑6) were detected to explore the value of these inflammatory markers in the assessment of traumatic shock patients. The clinical data of 80 patients with traumatic shock and infections in Zhangzhou Municipal Hospital of Fujian Province from January 2014 to December 2017 were collected as the experimental group. During the same period, 80 acute trauma patients who did not suffer from traumatic shock were regarded as the control group. According to the prognosis outcomes, the experimental group was divided into 56 patients with good prognosis and 24 patients with poor prognosis. Also the PCT, CRP and IL‑6 levels in serum of patients at admission (T1), 12 h after admission (T2), three days after admission (T3) and on day 7 (T4) were detected. The differences between the three inflammatory indicators, the pre‑admission injury severity score (ISS score), the acute physiology and chronic psychological score (APACHE II score) were compared between the good prognosis and the poor prognosis group. The serum CRP at the T4 time period was significantly lower than both the T1 and T2 time periods (P<0.05). There were differences in serum PCT, CRP and IL‑6 between the good prognosis and the poor prognosis group at the time of T1‑T4 (P<0.05). The expression levels of PCT, CRP and IL‑6 in the serum of patients with poor prognosis were higher than those with good prognosis (P<0.05). Pre‑admission ISS scores and APACHE II scores in patients with good prognosis were lower than those with poor prognosis (P<0.05). Detection of PCT, CRP and IL‑6 expression levels in serum of the patients has an important reference value for assessing the condition of patients with traumatic shock.

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June 2019
Volume 17 Issue 6

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APA
Li, Y., Chen, L., Fang, W., & Chen, H. (2019). Application value of procalcitonin, C‑reactive protein and interleukin‑6 in the evaluation of traumatic shock . Experimental and Therapeutic Medicine, 17, 4586-4592. https://doi.org/10.3892/etm.2019.7492
MLA
Li, Y., Chen, L., Fang, W., Chen, H."Application value of procalcitonin, C‑reactive protein and interleukin‑6 in the evaluation of traumatic shock ". Experimental and Therapeutic Medicine 17.6 (2019): 4586-4592.
Chicago
Li, Y., Chen, L., Fang, W., Chen, H."Application value of procalcitonin, C‑reactive protein and interleukin‑6 in the evaluation of traumatic shock ". Experimental and Therapeutic Medicine 17, no. 6 (2019): 4586-4592. https://doi.org/10.3892/etm.2019.7492