True hermaphroditism with seminoma: A case report

  • Authors:
    • Yulin Lai
    • Jiansen Xie
    • Peikai Tian
    • Liming Zhong
    • Liangchao Ni
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  • Published online on: November 8, 2018     https://doi.org/10.3892/mco.2018.1760
  • Pages: 97-100
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Abstract

The aim of the present study was to discuss the diagnosis and treatment of a patient with true hermaphroditism complicated by seminoma. The patient was a 35‑year‑old man who was admitted to the Peking University Shenzhen Hospital with a retractable mass in the left inguinal region for 20 years. A computed tomography examination revealed right cryptorchidism. The postoperative pathology suggested true hermaphroditism with a seminoma. The results of immunohistochemical examination were as follows: Sal‑like protein 4+ (partially weak); octamer‑binding transcription factor 4+ (partially weak); CD117+; cytokeratin+; CD30‑, α‑fetoprotein‑, inhibin‑α‑. The karyotype was 46, XY. Adult true hermaphroditism combined with seminoma is rare in clinical practice. Combined histopathological analysis, immunophenotype detection and karyotype analysis are of great value in the diagnosis and differential diagnosis. Early intervention and combined surgery with radiotherapy and chemotherapy can significantly improve the prognosis of such patients.
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January 2019
Volume 10 Issue 1

Print ISSN: 2049-9450
Online ISSN:2049-9469

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APA
Lai, Y., Xie, J., Tian, P., Zhong, L., & Ni, L. (2019). True hermaphroditism with seminoma: A case report. Molecular and Clinical Oncology, 10, 97-100. https://doi.org/10.3892/mco.2018.1760
MLA
Lai, Y., Xie, J., Tian, P., Zhong, L., Ni, L."True hermaphroditism with seminoma: A case report". Molecular and Clinical Oncology 10.1 (2019): 97-100.
Chicago
Lai, Y., Xie, J., Tian, P., Zhong, L., Ni, L."True hermaphroditism with seminoma: A case report". Molecular and Clinical Oncology 10, no. 1 (2019): 97-100. https://doi.org/10.3892/mco.2018.1760