Radiation‑induced glioblastoma with rhabdoid characteristics following treatment for medulloblastoma: A case report and review of the literature

  • Authors:
    • Ying Wang
    • Shujun Song
    • Xiaoming Su
    • Jihua Wu
    • Zhuojie Dai
    • Di Cui
    • Ye Reng
    • Jingjing Fan
    • Yulong Shen
    • Qingqin Wu
    • Zongye Wang
  • View Affiliations

  • Published online on: August 20, 2018     https://doi.org/10.3892/mco.2018.1703
  • Pages: 415-418
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Glioblastoma multiforme (GBM) is a high‑grade glioma that may develop from several other central nervous system tumors after radiation therapy. We herein report a case of GBM occurring 8 years after radiation therapy for medulloblastoma. The secondary tumor was histologically distinctly different from the primary tumor. Previously reported cases indicate that GBM induced by radiation therapy is associated with a highly aggressive clinical course with a high risk of early recurrence and poor prognosis. In addition, histological examination revealed that the tumor cells exhibited characteristics of both GBM and rhabdoid tumor cells. The diverse pathological characteristics of GBM may reflect the potential effects of radiation therapy on the tumor.
View Figures
View References

Related Articles

Journal Cover

October 2018
Volume 9 Issue 4

Print ISSN: 2049-9450
Online ISSN:2049-9469

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
APA
Wang, Y., Song, S., Su, X., Wu, J., Dai, Z., Cui, D. ... Wang, Z. (2018). Radiation‑induced glioblastoma with rhabdoid characteristics following treatment for medulloblastoma: A case report and review of the literature. Molecular and Clinical Oncology, 9, 415-418. https://doi.org/10.3892/mco.2018.1703
MLA
Wang, Y., Song, S., Su, X., Wu, J., Dai, Z., Cui, D., Reng, Y., Fan, J., Shen, Y., Wu, Q., Wang, Z."Radiation‑induced glioblastoma with rhabdoid characteristics following treatment for medulloblastoma: A case report and review of the literature". Molecular and Clinical Oncology 9.4 (2018): 415-418.
Chicago
Wang, Y., Song, S., Su, X., Wu, J., Dai, Z., Cui, D., Reng, Y., Fan, J., Shen, Y., Wu, Q., Wang, Z."Radiation‑induced glioblastoma with rhabdoid characteristics following treatment for medulloblastoma: A case report and review of the literature". Molecular and Clinical Oncology 9, no. 4 (2018): 415-418. https://doi.org/10.3892/mco.2018.1703