Low-dose ionizing radiation increases the mortality risk of solid cancers in nuclear industry workers: A meta-analysis

  • Authors:
    • Shu‑Gen Qu
    • Jin Gao
    • Bo Tang
    • Bo Yu
    • Yue‑Ping Shen
    • Yu Tu
  • View Affiliations

  • Published online on: March 19, 2018     https://doi.org/10.3892/mco.2018.1590
  • Pages: 703-711
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Abstract

Low-dose ionizing radiation (LDIR) may increase the mortality of solid cancers in nuclear industry workers, but only few individual cohort studies exist, and the available reports have low statistical power. The aim of the present study was to focus on solid cancer mortality risk from LDIR in the nuclear industry using standard mortality ratios (SMRs) and 95% confidence intervals. A systematic literature search through the PubMed and Embase databases identified 27 studies relevant to this meta‑analysis. There was statistical significance for total, solid and lung cancers, with meta‑SMR values of 0.88, 0.80, and 0.89, respectively. There was evidence of stochastic effects by IR, but more definitive conclusions require additional analyses using standardized protocols to determine whether LDIR increases the risk of solid cancer-related mortality.
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May 2018
Volume 8 Issue 5

Print ISSN: 2049-9450
Online ISSN:2049-9469

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APA
Qu, S., Gao, J., Tang, B., Yu, B., Shen, Y., & Tu, Y. (2018). Low-dose ionizing radiation increases the mortality risk of solid cancers in nuclear industry workers: A meta-analysis. Molecular and Clinical Oncology, 8, 703-711. https://doi.org/10.3892/mco.2018.1590
MLA
Qu, S., Gao, J., Tang, B., Yu, B., Shen, Y., Tu, Y."Low-dose ionizing radiation increases the mortality risk of solid cancers in nuclear industry workers: A meta-analysis". Molecular and Clinical Oncology 8.5 (2018): 703-711.
Chicago
Qu, S., Gao, J., Tang, B., Yu, B., Shen, Y., Tu, Y."Low-dose ionizing radiation increases the mortality risk of solid cancers in nuclear industry workers: A meta-analysis". Molecular and Clinical Oncology 8, no. 5 (2018): 703-711. https://doi.org/10.3892/mco.2018.1590