Current condition of genetic medicine for hereditary breast cancer

  • Authors:
    • Hiroko Terui‑Kohbata
    • Masayuki Yoshida
  • View Affiliations

  • Published online on: May 12, 2017     https://doi.org/10.3892/mco.2017.1260
  • Pages: 98-102
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Abstract

BRCA1 or BRCA2 (BRCA1/2) germline mutations, which cause hereditary breast and ovarian cancer syndrome, have been studied to develop targeted therapies for these associated cancer types. The BRCA1/2 test has been implemented in more than one hundred medical facilities in a clinical setting in Japan. The purpose of the current study is to document the prevalence and the awareness of genetic medicine for all hereditary breast cancer (HBC) including the BRCA1/2 test in Japan. The self‑administered questionnaire was sent to 120 medical facilities where the BRCA1/2 test was provided, and 83 health care professionals participated (response rate, 69.2%). Of the all respondents, 33.7% (N=42) were clinical geneticists, 31.3% (N=26) other physicians, 15.7% (N=13) genetic counselors and 2.4% (N=2) nurses. In the most recent one‑year period, in 83.1% of the 69 facilities the number of patients who underwent genetic testing for HBC was <10 and only 4 facilities provided multigene panel testing for HBC. In order to facilitate the access to genetic medicine, the majority of the genetic counselors (58.3%) recognized the need for education of healthcare professionals. Although the awareness of and interests in HBC have increased gradually, the equitable access to precision medicine is considered to be a challenging issue in Japan.
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July 2017
Volume 7 Issue 1

Print ISSN: 2049-9450
Online ISSN:2049-9469

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APA
Terui‑Kohbata, H., & Terui‑Kohbata, H. (2017). Current condition of genetic medicine for hereditary breast cancer. Molecular and Clinical Oncology, 7, 98-102. https://doi.org/10.3892/mco.2017.1260
MLA
Terui‑Kohbata, H., Yoshida, M."Current condition of genetic medicine for hereditary breast cancer". Molecular and Clinical Oncology 7.1 (2017): 98-102.
Chicago
Terui‑Kohbata, H., Yoshida, M."Current condition of genetic medicine for hereditary breast cancer". Molecular and Clinical Oncology 7, no. 1 (2017): 98-102. https://doi.org/10.3892/mco.2017.1260