Radiotherapy for urinary bladder pheochromocytoma with invasion of the prostate: A case report and literature review

  • Authors:
    • Dong You
    • Ruizhen Ren
    • Ercheng Chen
    • Shulin Chen
    • Dawei Wang
    • Jianhui Liu
  • View Affiliations

  • Published online on: March 17, 2016     https://doi.org/10.3892/mco.2016.820
  • Pages: 1060-1062
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Abstract

Malignant pheochromocytoma is a rare tumor, for which there is currently no effective therapy. Cytoreductive surgery is recommended to reduce tumor burden and relieve the symptoms of catecholamine excess, although complete eradication of the lesions is often not feasible. In patients with advanced disease, for whom surgical resection is not an option, systemic chemotherapy, radiotherapy and treatment with iodine‑131‑meta‑iodobenzylguanidine may be used to achieve symptomatic relief. Although malignant pheochromocytoma is considered to be unresponsive to radiotherapy, a limited number of case reports, although not large patient samples, have been published on the effectiveness of radiotherapy for the treatment of this disease. This is the case report of a 23‑year‑old male patient with bladder pheochromocytoma invading the prostate, who refused to undergo surgery. The tumor shrank following radiotherapy and had not increased in size 1.5 years after treatment. Similarly, the blood pressure of the patient remained within normal limits without antihypertensive medication; the levels of catecholamines and their metabolites also remained normal. Our case demonstrated that radiotherapy was effective for malignant pheochromocytoma to a certain extent and, therefore, it may be selected when surgery is not feasible.
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June 2016
Volume 4 Issue 6

Print ISSN: 2049-9450
Online ISSN:2049-9469

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APA
You, D., Ren, R., Chen, E., Chen, S., Wang, D., & Liu, J. (2016). Radiotherapy for urinary bladder pheochromocytoma with invasion of the prostate: A case report and literature review. Molecular and Clinical Oncology, 4, 1060-1062. https://doi.org/10.3892/mco.2016.820
MLA
You, D., Ren, R., Chen, E., Chen, S., Wang, D., Liu, J."Radiotherapy for urinary bladder pheochromocytoma with invasion of the prostate: A case report and literature review". Molecular and Clinical Oncology 4.6 (2016): 1060-1062.
Chicago
You, D., Ren, R., Chen, E., Chen, S., Wang, D., Liu, J."Radiotherapy for urinary bladder pheochromocytoma with invasion of the prostate: A case report and literature review". Molecular and Clinical Oncology 4, no. 6 (2016): 1060-1062. https://doi.org/10.3892/mco.2016.820