Open Access

Clinical characteristics and pathology of thyroid‑like follicular carcinoma of the kidney: Report of 3 cases and a literature review

  • Authors:
    • Fan Chen
    • Yang Wang
    • Xiuzhen Wu
    • Yaofeng Zhu
    • Xuewen Jiang
    • Shouzhen Chen
    • Zhaocun Zhang
    • Zhichuan Zou
    • Yue Yang
    • Kejia Zhu
    • Yong Wang
    • Jianfeng Cui
    • Ben‑Kang Shi
  • View Affiliations

  • Published online on: November 20, 2015     https://doi.org/10.3892/mco.2015.682
  • Pages: 143-150
  • Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Thyroid‑like follicular carcinoma (TLFC) of the kidney is an extremely rare type of renal tumor, which has not been classified under a known subtype of renal cell carcinoma. It is histologically similar to the primary thyroid follicular carcinoma; however, the characteristics lack thyroid immunohistochemical markers. The aim of the present study was to illustrate the clinical characteristics of 3 new cases along with a review of the literature. The patients were compared with regards to gender, age, location and size of the tumor, imageology, morphology, immunohistochemistry and prognosis. According to the limited data, TLFC occurs mainly in young women and its clinical manifestations have no difference with other renal tumors. Its imageological features resemble a large spectrum of benign and malignant renal and extra‑renal conditions, which should be eliminated in the diagnostic process. Confirmed diagnosis depends on the examination of pathology and immunohistochemistry. Surgical ablation is the preferred therapeutic method. Currently, TLFC has a relatively good prognosis; however, this conclusion requires further cases and long‑term follow‑ups. Improving the understanding of TLFC can help avoid misdiagnosis and prevent inappropriate treatment.
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February 2016
Volume 4 Issue 2

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Copy and paste a formatted citation
APA
Chen, F., Wang, Y., Wu, X., Zhu, Y., Jiang, X., Chen, S. ... Shi, B. (2016). Clinical characteristics and pathology of thyroid‑like follicular carcinoma of the kidney: Report of 3 cases and a literature review. Molecular and Clinical Oncology, 4, 143-150. https://doi.org/10.3892/mco.2015.682
MLA
Chen, F., Wang, Y., Wu, X., Zhu, Y., Jiang, X., Chen, S., Zhang, Z., Zou, Z., Yang, Y., Zhu, K., Wang, Y., Cui, J., Shi, B."Clinical characteristics and pathology of thyroid‑like follicular carcinoma of the kidney: Report of 3 cases and a literature review". Molecular and Clinical Oncology 4.2 (2016): 143-150.
Chicago
Chen, F., Wang, Y., Wu, X., Zhu, Y., Jiang, X., Chen, S., Zhang, Z., Zou, Z., Yang, Y., Zhu, K., Wang, Y., Cui, J., Shi, B."Clinical characteristics and pathology of thyroid‑like follicular carcinoma of the kidney: Report of 3 cases and a literature review". Molecular and Clinical Oncology 4, no. 2 (2016): 143-150. https://doi.org/10.3892/mco.2015.682