SERUM PLACENTAL-TYPE ALKALINE-PHOSPHATASE LEVELS IN PATIENTS WITH EPITHELIAL OVARIAN-CARCINOMA

  • Authors:
    • TEJ IND
    • RK ILES
    • K DESOUZA
    • P CARTER
    • D LOWE
    • JH SHEPHERD
    • CN HUDSON
    • T CHARD
  • View Affiliations

  • Published online on: February 1, 1995     https://doi.org/10.3892/ijo.6.2.385
  • Pages: 385-389
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Abstract

Serum placental alkaline phosphatase (PLAP)-type immunoreactivity was measured in 190 women with epithelial ovarian malignancy, 27 women with borderline ovarian cancer and 334 control subjects with non-neoplastic or benign gynaecological disease. Smoking, ABO blood group and menopausal status affect serum concentrations of PLAP and results were corrected for these. Circulating levels were elevated in patients with cancer and increased with stage. Levels were unaltered in borderline ovarian disease. Two-year stage corrected survival analysis demonstrated a significant worsening of prognosis in patients with serum PLAP-type levels greater than the 100th centile for controls.

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February 1995
Volume 6 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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APA
IND, T., ILES, R., DESOUZA, K., CARTER, P., LOWE, D., SHEPHERD, J. ... CHARD, T. (1995). SERUM PLACENTAL-TYPE ALKALINE-PHOSPHATASE LEVELS IN PATIENTS WITH EPITHELIAL OVARIAN-CARCINOMA. International Journal of Oncology, 6, 385-389. https://doi.org/10.3892/ijo.6.2.385
MLA
IND, T., ILES, R., DESOUZA, K., CARTER, P., LOWE, D., SHEPHERD, J., HUDSON, C., CHARD, T."SERUM PLACENTAL-TYPE ALKALINE-PHOSPHATASE LEVELS IN PATIENTS WITH EPITHELIAL OVARIAN-CARCINOMA". International Journal of Oncology 6.2 (1995): 385-389.
Chicago
IND, T., ILES, R., DESOUZA, K., CARTER, P., LOWE, D., SHEPHERD, J., HUDSON, C., CHARD, T."SERUM PLACENTAL-TYPE ALKALINE-PHOSPHATASE LEVELS IN PATIENTS WITH EPITHELIAL OVARIAN-CARCINOMA". International Journal of Oncology 6, no. 2 (1995): 385-389. https://doi.org/10.3892/ijo.6.2.385