TISSUE CEA AND TPA EXPRESSION IN STAGE-I BREAST-CANCER

  • Authors:
    • F GENTA
    • B GHIRINGHELLO
    • G BOTTA
    • C DESANCTIS
    • D KATSAROS
    • MP MANO
    • P SISMONDI
  • View Affiliations

  • Published online on: February 1, 1994     https://doi.org/10.3892/ijo.4.2.449
  • Pages: 449-452
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Abstract

Tumoral Carcino Embryonic Antigen (CEA) and Tissue Polypeptide Antigen (TPA) expression was investigated by immunoperoxidase technique on paraffin embedded tissues of 191 patients with infiltrating breast cancer and negative axillary nodes. TPA was almost always detected at high levels. CEA staining was evenly distributed, but high CEA positivity was associated with higher TPA expression. Lower levels of both markers were found in medullar carcinomas as well as in cancers larger than 1 cm. Higher estrogen and progesterone receptor content was associated with higher expression of tissue CEA and TPA. After a median follow-up of 9 years, neither tissue CEA nor tissue TPA show any prognostic value.

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February 1994
Volume 4 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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APA
GENTA, F., GHIRINGHELLO, B., BOTTA, G., DESANCTIS, C., KATSAROS, D., MANO, M., & SISMONDI, P. (1994). TISSUE CEA AND TPA EXPRESSION IN STAGE-I BREAST-CANCER. International Journal of Oncology, 4, 449-452. https://doi.org/10.3892/ijo.4.2.449
MLA
GENTA, F., GHIRINGHELLO, B., BOTTA, G., DESANCTIS, C., KATSAROS, D., MANO, M., SISMONDI, P."TISSUE CEA AND TPA EXPRESSION IN STAGE-I BREAST-CANCER". International Journal of Oncology 4.2 (1994): 449-452.
Chicago
GENTA, F., GHIRINGHELLO, B., BOTTA, G., DESANCTIS, C., KATSAROS, D., MANO, M., SISMONDI, P."TISSUE CEA AND TPA EXPRESSION IN STAGE-I BREAST-CANCER". International Journal of Oncology 4, no. 2 (1994): 449-452. https://doi.org/10.3892/ijo.4.2.449