Enhanced apoptosis in retrovirally transfected osteosarcoma cells after exposure to sodium butyrate.

  • Authors:
    • S Moalic
    • B Liagre
    • F Labrousse
    • J L Beneytout
  • View Affiliations

  • Published online on: April 1, 2000     https://doi.org/10.3892/ijo.16.4.695
  • Pages: 695-1395
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

We investigated the effects of sodium butyrate (NaBu) on two retrovirally transfected osteosarcoma cell lines (1547-TK and 1547-LacZ cells) compared to the corresponding untransfected cell line. The first finding was an inhibitory effect only on the proliferation of both transfected cell lines. This antiproliferative effect was associated with apoptosis induction, which was detected using techniques that monitor either characteristic biochemical or morphological processes. Our findings show that 1547-TK and 1547-LacZ cells were much more sensitive to NaBu treatment than untransfected 1547 cells as concerns both proliferation and apoptosis induction.

Related Articles

Journal Cover

April 2000
Volume 16 Issue 4

Print ISSN: 1019-6439
Online ISSN:1791-2423

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
APA
Moalic, S., Liagre, B., Labrousse, F., & Beneytout, J. (2000). Enhanced apoptosis in retrovirally transfected osteosarcoma cells after exposure to sodium butyrate.. International Journal of Oncology, 16, 695-1395. https://doi.org/10.3892/ijo.16.4.695
MLA
Moalic, S., Liagre, B., Labrousse, F., Beneytout, J."Enhanced apoptosis in retrovirally transfected osteosarcoma cells after exposure to sodium butyrate.". International Journal of Oncology 16.4 (2000): 695-1395.
Chicago
Moalic, S., Liagre, B., Labrousse, F., Beneytout, J."Enhanced apoptosis in retrovirally transfected osteosarcoma cells after exposure to sodium butyrate.". International Journal of Oncology 16, no. 4 (2000): 695-1395. https://doi.org/10.3892/ijo.16.4.695