Non-metastatic Ewing's sarcoma: twenty years of experience suggests that surgery is a prime factor for successful multimodality therapy.

  • Authors:
    • S S Givens
    • S Y Woo
    • L Y Huang
    • T A Rich
    • M H Maor
    • A Cangir
    • J A Murray
    • M J Oswald
    • L J Peters
    • N Jaffe
  • View Affiliations

  • Published online on: June 1, 1999     https://doi.org/10.3892/ijo.14.6.1039
  • Pages: 1039-1082
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Abstract

Eighty-five patients (37 female, 48 male; median age 14 years) with non-metastatic Ewing's sarcoma received definitive treatment at the University of Texas M.D. Anderson Cancer Center between 1969 and 1988. Multidisciplinary therapy was administered as follows: combination chemotherapy (CC) and local radiotherapy (XRT): 65 patients; CC, XRT and surgery, 19 patients; and XRT and surgery, 1 patient. This permitted a 10-20 year follow-up for 75% of our patients. The overall survival at 5 and 10-20 years was 46.1%, and 37.2%, respectively. At 5 years, 80.5% of live patients had control of local disease. The influence of sex, age, ethnicity, primary site, size, lactic dehydrogenase (LDH) level, presence or absence of systemic symptoms, and XRT dose (<60 Gy and

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Jun 1999
Volume 14 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

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APA
Givens, S., Woo, S., Huang, L., Rich, T., Maor, M., Cangir, A. ... Jaffe, N. (1999). Non-metastatic Ewing's sarcoma: twenty years of experience suggests that surgery is a prime factor for successful multimodality therapy.. International Journal of Oncology, 14, 1039-1082. https://doi.org/10.3892/ijo.14.6.1039
MLA
Givens, S., Woo, S., Huang, L., Rich, T., Maor, M., Cangir, A., Murray, J., Oswald, M., Peters, L., Jaffe, N."Non-metastatic Ewing's sarcoma: twenty years of experience suggests that surgery is a prime factor for successful multimodality therapy.". International Journal of Oncology 14.6 (1999): 1039-1082.
Chicago
Givens, S., Woo, S., Huang, L., Rich, T., Maor, M., Cangir, A., Murray, J., Oswald, M., Peters, L., Jaffe, N."Non-metastatic Ewing's sarcoma: twenty years of experience suggests that surgery is a prime factor for successful multimodality therapy.". International Journal of Oncology 14, no. 6 (1999): 1039-1082. https://doi.org/10.3892/ijo.14.6.1039