Identification of cytochrome P450s in human glioma cell line.

  • Authors:
    • H G Vasquez
    • H Strobel
  • View Affiliations

  • Published online on: June 1, 1998     https://doi.org/10.3892/ijo.12.6.1291
  • Pages: 1291-1295
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Abstract

Five different isoforms of cytochrome P450 including 1A1, 1A2, 2E1, 2A and 2B6 have been identified in human glioma Hs 683 cell line using RT-PCR reaction. These isoforms belong to four distinct subfamilies. The effect of benzanthracene (Ba) as inducer was tested on the mRNA level of cytochrome P450 1A1. Northern blot analysis clearly showed an induction response from these cells to Ba in a proportion that is comparable to the induction seen in rat glioma cells.

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June 1998
Volume 12 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

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APA
Vasquez, H., & Vasquez, H. (1998). Identification of cytochrome P450s in human glioma cell line.. International Journal of Oncology, 12, 1291-1295. https://doi.org/10.3892/ijo.12.6.1291
MLA
Vasquez, H., Strobel, H."Identification of cytochrome P450s in human glioma cell line.". International Journal of Oncology 12.6 (1998): 1291-1295.
Chicago
Vasquez, H., Strobel, H."Identification of cytochrome P450s in human glioma cell line.". International Journal of Oncology 12, no. 6 (1998): 1291-1295. https://doi.org/10.3892/ijo.12.6.1291