HLA class I and advanced melanoma in Israeli Jews

  • Authors:
    • J Schachter
    • T Klein
    • B Klein
    • A Adler
  • View Affiliations

  • Published online on: March 1, 1997     https://doi.org/10.3892/ijo.10.3.645
  • Pages: 645-648
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Abstract

KLA class I antigen was studied in Jewish melanoma patients. The frequency of HLA A24, A26 and B38 was significantly higher in the melanoma patients (34.7%, 39.1% and 38.6%, respectively) compared to controls (16.6%, 18.5% and 20.6%, respectively) (p<0.005). HLA A24 antigen was significantly higher in the metastatic patients (44.8%) compared to the non-metastatic (11.1%) (p<0.001). The frequency of this antigen was also higher in the patients with recurrent disease (16.6%) than in the high risk patients with no recurrence (11.1%). HLA class I and A24 may play a role in the biologic behavior of malignant melanoma.

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March 1997
Volume 10 Issue 3

Print ISSN: 1019-6439
Online ISSN:1791-2423

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APA
Schachter, J., Klein, T., Klein, B., & Adler, A. (1997). HLA class I and advanced melanoma in Israeli Jews. International Journal of Oncology, 10, 645-648. https://doi.org/10.3892/ijo.10.3.645
MLA
Schachter, J., Klein, T., Klein, B., Adler, A."HLA class I and advanced melanoma in Israeli Jews". International Journal of Oncology 10.3 (1997): 645-648.
Chicago
Schachter, J., Klein, T., Klein, B., Adler, A."HLA class I and advanced melanoma in Israeli Jews". International Journal of Oncology 10, no. 3 (1997): 645-648. https://doi.org/10.3892/ijo.10.3.645