Differences of ploidy status in progression of head and neck melanomas

  • Authors:
    • M Korabiowska
    • U Brinckmann
    • S Kellner
    • U Brinck
    • J Stachura
    • A Schauer
  • View Affiliations

  • Published online on: February 1, 1997     https://doi.org/10.3892/ijo.10.2.381
  • Pages: 381-385
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Abstract

Thirty-three common naevi, 26 dysplastic naevi, 58 primary melanomas of facial skin, 24 oral melanomas, 32 lymph nodes and 12 distant melanoma metastases were stained using Feulgen method to evaluate the ploidy status by image analysis GAS-200 system. Eight percent of common naevi, 22% of dysplastic naevi, 43% of facial melanomas, 65% of oral melanomas, 40% of lymph nodes with melanoma metastases and 66% of distant melanoma metastases were classified as aneuploid. In facial melanomas the percentage of aneuploid cases increased with Clark level. Survival time of patients was significantly shorter for aneuploid cases as compared to euploid ones (p <0.01).

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February 1997
Volume 10 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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APA
Korabiowska, M., Brinckmann, U., Kellner, S., Brinck, U., Stachura, J., & Schauer, A. (1997). Differences of ploidy status in progression of head and neck melanomas. International Journal of Oncology, 10, 381-385. https://doi.org/10.3892/ijo.10.2.381
MLA
Korabiowska, M., Brinckmann, U., Kellner, S., Brinck, U., Stachura, J., Schauer, A."Differences of ploidy status in progression of head and neck melanomas". International Journal of Oncology 10.2 (1997): 381-385.
Chicago
Korabiowska, M., Brinckmann, U., Kellner, S., Brinck, U., Stachura, J., Schauer, A."Differences of ploidy status in progression of head and neck melanomas". International Journal of Oncology 10, no. 2 (1997): 381-385. https://doi.org/10.3892/ijo.10.2.381