METHYLATION OF CHROMOSOME 11P GENES IN WILMS-TUMOR AND KIDNEY TISSUE

  • Authors:
    • JC WILLIAMS
    • NJ MAITLAND
    • MG MOTT
    • KW BROWN
  • View Affiliations

  • Published online on: December 1, 1992     https://doi.org/10.3892/ijo.1.7.743
  • Pages: 743-746
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Abstract

Three genes on the short arm of chromosome 11 (WT1, IGF2 and HRAS) were hypomethylated in Wilms' tumour tissue compared to normal kidney tissue, and one (CALCA) was hypermethylated. IGF2 and HRAS showed evidence of allele-specific methylation, which may indicate genomic imprinting of the 11p15 region in some kidney cells.

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December 1992
Volume 1 Issue 7

Print ISSN: 1019-6439
Online ISSN:1791-2423

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APA
WILLIAMS, J., MAITLAND, N., MOTT, M., & BROWN, K. (1992). METHYLATION OF CHROMOSOME 11P GENES IN WILMS-TUMOR AND KIDNEY TISSUE. International Journal of Oncology, 1, 743-746. https://doi.org/10.3892/ijo.1.7.743
MLA
WILLIAMS, J., MAITLAND, N., MOTT, M., BROWN, K."METHYLATION OF CHROMOSOME 11P GENES IN WILMS-TUMOR AND KIDNEY TISSUE". International Journal of Oncology 1.7 (1992): 743-746.
Chicago
WILLIAMS, J., MAITLAND, N., MOTT, M., BROWN, K."METHYLATION OF CHROMOSOME 11P GENES IN WILMS-TUMOR AND KIDNEY TISSUE". International Journal of Oncology 1, no. 7 (1992): 743-746. https://doi.org/10.3892/ijo.1.7.743