Open Access

Risk factors and preventive measures of cerebral hyperperfusion syndrome after carotid artery interventional therapy

  • Authors:
    • Shibo Wang
    • Jing Han
    • Lei Cheng
    • Nengpeng Li
  • View Affiliations

  • Published online on: July 17, 2017     https://doi.org/10.3892/etm.2017.4796
0

Abstract

This study sought to investigate the risk factors for cerebral hyperperfusion syndrome (CHS) after carotid artery interventional therapy, and to explore potential preventive measures. Three hundred and eighty-two patients treated with carotid artery stenting at the Huanhu Hospital (Tianjin, China) between January 2010 and January 2016 were divided into CHS and non-CHS groups. A retrospective analysis of patient clinical data was made. The CHS group had more patients presenting coronary heart disease, diabetes, progressive neurological disease and transient recurrent cerebral hemorrhage than the non-CHS group. More patients in the CHS group presented stenosis of the internal carotid artery siphon. More CHS group patients showed plaque formation extending >3 cm to the distal end of the internal carotid artery. Finally, more CHS group patients had pressure gradients >60 mmHg (p<0.05). Logistics regression analysis showed that preoperative diabetes mellitus and carotid pressure gradient ≥60 mmHg were independent risk factors for CHS (p<0.05). The ROC curve of carotid pressure gradients ≥60 mmHg were made to predict CHS, with the area under curve being 0.949 (p<0.05). The best cut-off value was 60 mmHg. Therefore, preoperative diabetes and a carotid pressure gradient ≥60 mmHg are risk factors for CHS, and these indicators need to be examined prior to operation.

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Print ISSN: 1792-0981
Online ISSN:1792-1015

2016 Impact Factor: 1.261
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APA
Wang, S., Han, J., Cheng, L., & Li, N. (1899). Risk factors and preventive measures of cerebral hyperperfusion syndrome after carotid artery interventional therapy. Experimental and Therapeutic Medicine, 0, 0-0. https://doi.org/10.3892/etm.2017.4796
MLA
Wang, S., Han, J., Cheng, L., Li, N."Risk factors and preventive measures of cerebral hyperperfusion syndrome after carotid artery interventional therapy". Experimental and Therapeutic Medicine 0.0 (1899): 0-0.
Chicago
Wang, S., Han, J., Cheng, L., Li, N."Risk factors and preventive measures of cerebral hyperperfusion syndrome after carotid artery interventional therapy". Experimental and Therapeutic Medicine 0, no. 0 (1899): 0-0. https://doi.org/10.3892/etm.2017.4796