Syphilis manifesting as a nasopharyngeal carcinoma with cervical lymphadenopathy: A case report

  • Authors:
    • Xinbin Pan
    • Xiaodong Zhu
    • Qingdi Quentin Li
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  • Published online on: April 2, 2012     https://doi.org/10.3892/etm.2012.535
  • Pages: 1023-1025
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Abstract

The present case report describes a case of syphilitic lymphadenopathy and raises the awareness of the differential diagnosis of cervical lymphadenopathy. A 50-year-old male worker presented with a 6-month history of enlarged and growing lymph nodes in the right upper neck and a blood-tinged post-nasal drip. Physical examination showed multiple enlarged lymph nodes located in the right upper neck. On nasopharyngoscopy, a mass was found in the nasopharynx. The histopathology of both the nasopharyngeal mass and the enlarged lymph nodes revealed non-specific inflammation. Rapid plasma reagin test results (titer, 1:1280) and Treponema pallidum particle assay results (titer, 1:2560) were positive. Subsequently, a diagnosis of syphilis was confirmed clinically and serologically. The reaction after penicillin treatment further confirmed the syphilis diagnosis. Thus, syphilis should be considered as a possibility in the differential diagnosis of cervical lymphadenopathy.
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June 2012
Volume 3 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

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APA
Pan, X., Zhu, X., & Li, Q.Q. (2012). Syphilis manifesting as a nasopharyngeal carcinoma with cervical lymphadenopathy: A case report. Experimental and Therapeutic Medicine, 3, 1023-1025. https://doi.org/10.3892/etm.2012.535
MLA
Pan, X., Zhu, X., Li, Q. Q."Syphilis manifesting as a nasopharyngeal carcinoma with cervical lymphadenopathy: A case report". Experimental and Therapeutic Medicine 3.6 (2012): 1023-1025.
Chicago
Pan, X., Zhu, X., Li, Q. Q."Syphilis manifesting as a nasopharyngeal carcinoma with cervical lymphadenopathy: A case report". Experimental and Therapeutic Medicine 3, no. 6 (2012): 1023-1025. https://doi.org/10.3892/etm.2012.535