Open Access

Advances in glucose metabolism research in colorectal cancer (Review)

  • Authors:
    • Sitian Fang
    • Xiao Fang
  • View Affiliations

  • Published online on: July 18, 2016     https://doi.org/10.3892/br.2016.719
  • Pages: 289-295
  • Copyright: © Fang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Cancer cells uptake glucose at a higher rate and produce lactic acid rather than metabolizing pyruvate through the tricarboxylic acid cycle. This adaptive metabolic shift is termed the Warburg effect. Recently progress had been made regarding the mechanistic understanding of glucose metabolism and associated diagnostic and therapeutic methods, which have been investigated in colorectal cancer. The majority of novel mechanisms involve important glucose metabolism associated genes and miRNA regulation. The present review discusses the contribution of these research results to facilitate with the development of novel diagnosis and anticancer treatment options.
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September-2016
Volume 5 Issue 3

Print ISSN: 2049-9434
Online ISSN:2049-9442

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APA
Fang, S., & Fang, S. (2016). Advances in glucose metabolism research in colorectal cancer (Review). Biomedical Reports, 5, 289-295. https://doi.org/10.3892/br.2016.719
MLA
Fang, S., Fang, X."Advances in glucose metabolism research in colorectal cancer (Review)". Biomedical Reports 5.3 (2016): 289-295.
Chicago
Fang, S., Fang, X."Advances in glucose metabolism research in colorectal cancer (Review)". Biomedical Reports 5, no. 3 (2016): 289-295. https://doi.org/10.3892/br.2016.719