miR‑181b as a key regulator of the oncogenic process and its clinical implications in cancer (Review)

  • Authors:
    • Juan Liu
    • Weifeng Shi
    • Changping Wu
    • Jingfang Ju
    • Jingting Jiang
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  • Published online on: November 7, 2013     https://doi.org/10.3892/br.2013.199
  • Pages: 7-11
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Abstract

MicroRNAs (miRNAs or miRs) are small, non‑coding, single‑stranded RNA molecules that regulate gene expression at the post‑transcriptional level to repress protein expression of target genes. Among these, miR‑181b has been found to be a critical regulatory miRNA linking inflammation and cancer. The functional significance of miR‑181b in various tumors and translational research suggests that it exhibits great potential as a predictive and prognostic biomarker. Extensive efforts are underway to identify mRNA targets and the affected regulatory networks, which may be the key to providing a better understanding of miR‑181b‑mediated signaling pathways.
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December 2013
Volume 2 Issue 1

Print ISSN: 2049-9434
Online ISSN:2049-9442

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APA
Liu, J., Shi, W., Wu, C., Ju, J., & Jiang, J. (2013). miR‑181b as a key regulator of the oncogenic process and its clinical implications in cancer (Review). Biomedical Reports, 2, 7-11. https://doi.org/10.3892/br.2013.199
MLA
Liu, J., Shi, W., Wu, C., Ju, J., Jiang, J."miR‑181b as a key regulator of the oncogenic process and its clinical implications in cancer (Review)". Biomedical Reports 2.1 (2013): 7-11.
Chicago
Liu, J., Shi, W., Wu, C., Ju, J., Jiang, J."miR‑181b as a key regulator of the oncogenic process and its clinical implications in cancer (Review)". Biomedical Reports 2, no. 1 (2013): 7-11. https://doi.org/10.3892/br.2013.199